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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    X-ploring Fragile X: The Science Behind the Syndrome
    Fragile X Syndrome is an X-linked genetic disorder resulting from the impairment of transcription of the FMR1 gene, producing less to no FMRP protein. FMRP is a translational inhibitor that plays a...

    Keywords: epigeneticsgene regulationtranscriptioncentral dogmatranslationFragile X syndromeSphingosine Metabolism

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    Disturbance and Succession an Active Learning Lecture
    Learning Objectives: Identify and understand examples of disturbance --- Provide examples of and know/understand the differences between primary and secondary succession --- Know how ecologists...

    Keywords: wildlifelandscape ecologydisturbanceintermediate disturbance hypothesisfiresuccessionsmokey bearlandscape managementchronosequenceprimary successionsecondary succession

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    Trail Camera Field Survey Module
    This QUBES module introduces high school students to the exciting world of field surveys using trail cameras. Designed for environmental science classes, the module offers a hands-on approach to...

    Keywords: graphsspecies richnessCommunity EcologymammalsMicrosoft Exceldichotomous keycamera trapsShannon diversity indexTrail CamerasPivotTables

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    Adapting a Traditional Laboratory Exercise to Become Inquiry Based: An Example With an Introductory Biology Lab in Diffusion
    Authentic research experiences are effective in fostering self-efficacy and increasing retention in STEM, particularly among minoritized student populations. Many instructors have sought to bring...

    Keywords: protocolquestionDiffusionVariableshypothesisscience processcontrolscientific efficacy

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    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...

    Keywords: bioethicsCRISPR/Cas9Genetic modificationGene drives

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    Analyzing Data on Behavioral and Immunological Effects of Inflammation in Mice
    In this activity, students will learn about behavioral and immunological responses to a bacterial infection. The activity emphasized the host’s responses rather than bacterial manipulation of the...

    Keywords: Vision and Changedata analysisImmunologybehaviorphysiologyinflammationinterdisciplinary educationAntigenmouseImmunoReachSicknessleukocyteneutrophilLipopolysaccharideacute phase response

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    A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature
    Many undergraduate students receive little guidance on how to critically read, interpret data within, or present information from the primary scientific literature before they begin senior...

    Keywords: primary literaturejournal clubScience CommunicationfeedbackPeer reviewgroup workOral presentationProcess skillsPeer evaluationDevelopmental neurobiology

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    Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar
    This unit, Defining Life, engages students in thinking like scientists, applying creativity to science, and learning biology core concepts as they explore the defining characteristics of life. This...

    Keywords: Evolutionbiologycellprocess of science

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    A Structured Inquiry-Based Module for the Undergraduate Cell Biology Laboratory That Teaches Fundamental Concepts of Cell Differentiation
    Pedagogical research in science education has shown that students effectively learn science by doing science. As a result, there is increased interest in bringing research-like experiences into the...

    Keywords: fluorescence microscopygene expressionpolymerase chain reactionCell Structurecell culturewestern blottingdifferentiationreverse transcription

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    Exploring Microbial Diversity: An Interactive In-Class Assignment for Biology and Microbiology Courses
    This interactive assignment engages students in a hands-on exploration of microbial diversity and the importance of microbes in ecosystems. Designed for General Biology II and Introduction to...

    Keywords: Microbiology EducationMicrobial DiversitymicrobiologyEcological Society of Americaecology educationresearch-based classroom instruction4DEE Framework

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    Learning the Landscape: An Active and Applied Lesson on Landscape Ecology for General Ecology Courses
    Landscape ecology is an important subtopic of ecology. As a field, it is inherently interdisciplinary and provides opportunities to teach not only content, but transferable ecological and...

    Keywords: landscape ecologyspatial scaleecosystem managementHabitat fragmentation

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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    Learn Biological Sciences and Physics through scientific process, creation, experimentation and analysis
    Microbes remain attached and grow on various surfaces whether living or non-living. These surfaces provide differential growth substances for microbes to remain attached or grow. The differential...

    Keywords: data analysisscientific methodphysicshands-onScientific InquirymicrobesBiological SciencesSpectrophotometer

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    Breaking It Down: What Factors Control Microbial Decomposition Rates?
    Demonstrating and modeling changes in ecosystem processes in the laboratory classroom can be logistically difficult and expensive. This complexity often leaves little time for students to generate...

    Keywords: data analysishypothesis testingdata visualizationdata managementMicrobial RespirationDecompostionAbiotic ConditionsResults Communication

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    Introductory Data Science Pipeline Activity – Yellow Fever and Global Precipitation
    Students follow the steps of a tiny data science project from start to finish. They are given a research question "Are the number of cases of yellow fever associated with global average...

    Keywords: graphinghypothesis testingdata scienceData-based inquiry in the classroomglobal healthdata science educationyellow fever

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    Colorful wings send messages: Why are butterfly wings colorful?
    Red postman butterflies live in tropical rainforests and have a mix of red, yellow, and black on their wings. These bright colors may warn predators or attract mates. Explore whether color alone or...

    Keywords: Quantitative reasoningadaptationpredationfield workEvolution by natural selection and mutation

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    Keep It Shrimple: An Adaptable Student-Driven Research Project for the Introductory Biology Laboratory
    A challenge in introductory biology laboratory courses is to provide students with authentic, engaging research opportunities that allow them to take ownership of their experiments. We present a...

    Keywords: hypothesis testingexperimental designanimal behaviorbrine shrimp

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    Learn Biological Sciences and Mathematics through cellular respiration, photosynthesis and primary productivity.
    Photosynthesis is a process by which plants synthesize glucose and oxygen in presence of sunlight through light dependent reactions by utilization of sunlight, water to synthesize oxygen, ATP and...

    Keywords: mathematicssimulationThe Analysis of Biological DataMetabolic Pathwaysprocess of sciencephotosynthesisqbccBiological ScienceshypothesisCellular Respirationprimary productivity

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    Marsh Madness: Using Video Games and a Case Study to Explore Food Webs and Ecosystem Services in Carpinteria Salt Marsh Reserve
    As the complexity and interconnectedness of our world increases, we are continually expected to be capable of complex, non-linear thinking in order to successfully tackle and solve the challenges...

    Keywords: food webssystems thinkingGame Based LearningEcosystem Servicessocio-ecological networks

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    Agents of change: Determining effects of pollution on marine environments through data interpretation
    In this lesson, students discuss the effects of disturbance in marine environments with a focus on pollution. They also evaluate the anthropogenic causes and consequences of pollution on a variety...

    Keywords: fishgraph interpretationfmnmarine ecosystemsmarine ecologymicroplastic pollutionEcological Disturbanceintermediate disturbance hypothesisstudent STEM identitypollutionBioGraphIrepresentation in STEMoil spill

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