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    2015-Zhang-EtAl-On the Selection of ODE Models with Application to Predator-Prey Dynamical Models
    We propose a computationally inexpensive approach that employs statistical estimation of the full model, followed by a combination of a least squares approximation (LSA) and the adaptive Lasso.

    Keywords: least-squares approximationSpline modelingMonte Carlo simulationsvariable selectionadaptive LASSO

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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.

    Keywords: compartment modelpharmacokineticsnonlinear estimationone compartment model

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    Investigating the Drivers of Western Monarch Decline Using Partial Least Squares Regression
    In this lesson, students will explore the drivers of the western monarch butterfly decline. Students will compare the effects of climate factors and land use factors on the western monarch...

    Keywords: RStudiomultivariate analysisMonarch butterfliesPartial Least Squares Regression

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    Working with plant phenology data and fitting a nonlinear model using least squares in R
    A participatory live-coding lesson on working with NEON phenology data and fitting a sine-wave model to determine when different species get and lose their leaves.

    Keywords: modelingRphenologyNEONRstatscodeparticipatory live-coding

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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not...

    Keywords: sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search

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    Striped Bass: A Regulatory Success Story
    This module examines the Maryland striped bass moratorium (1985-1989) as a fisheries management success story. Maryland DNR striped bass young of the year data is utilized for least squares linear...

    Keywords: regressionfisheriesmonitoringrecruitmentstriped bassmoratoriumfish biologyfisheries ecologyspawninganadromousyoung of the yearrelative abundancechesapeake bayfish population

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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.

    Keywords: microbiologyLotka Volterrramicrobiota

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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters...

    Keywords: time seriesEvaluation SPLINEgeneleast squaresbifurcation

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    1-066-USCensusModeling-ModelingScenario
    The United States Census, conducted every 10 years, gives data on the United States population, that can be modeled with the exponential, logistic, or Gompertz functions.

    Keywords: datalogisticpopulationGompertzcensusgoodness of fit

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    2013-Fathalla_Rihan-Delay Differential Equations in Biosciences - Parameter estimation and sensitivity analysis
    This is a review article to show that delay differential models have a richer mathematical framework (compared with models without memory or after-effects) and a better consistency with biological...

    Keywords: epidemiologysensitivityImmunologyphysiologyRK-methodstime-lags

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    Linked Genes and Recombination: Advanced Punnett Squares
    An online module in which students learn about more difficult genetics problems, including linked genes and crossing over. Quantitatively students learn about marginal probabilities and chi-square...

    Keywords: geneticsProbabilityResources @ MathBenchonlinepunnett squareslinked genes

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    Math Bench Probability and Statistics: Mice with Fangs - Intro to Punnett Squares
    This is an online activity that provides an introduction to Punnett squares as a tool for visualizing genetic inheritance. The ratios of possible genotypes and phenotypes in offspring are...

    Keywords: geneticsResources @ MathBenchonlineMathBenchpunnett squares

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    More Mice with Fangs: Intermediate Punnett Squares
    An online module utilizing probability and Punnett squares to introduce students to more complex genetic problems. The module emphasizes students' use of probability to solve the problems.

    Keywords: geneticsProbabilityResources @ MathBenchonlinepunnett squares

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    SIMIODE Spring 2024 Webinars - WikiModel
    WikiModel is cloud-based application and requires no installation and is run via a web-browser to facilitate rapid implementation. Equations are typed in as they appear in a textbook. ODEs are...

    Keywords: modelingSoftwaretoolapplicationWikiModelmodeling cycle

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    3-090-OneSpringMass-ModelingScenario
    We lead students through building a mathematical model for a single mass (bob)-spring system that is hanging vertically. We also lead the students, using data that they collect together with their...

    Keywords: undampedsum of square errorsmass springHooke's Lawoscilationleast-squares approximation

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    6-026-IsleRoyaleModeling-ModelingScenario
    The primary aim of this project is to draw a connection between differential equations and vector calculus, using population ecology modeling as a vehicle.

    Keywords: ecologyoptimizationpredator-preypopulationvector calculusLagrange multipliersleast squaresIslel Royale

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    Fitting Exponential and Logistic Growth Models to Bacterial Cell Count Data
    In this activity, students will model a noisy set of bacterial cell count data using both exponential and logistic growth models. For each model the students will plot the data (or a linear...

    Keywords: modelingdata analysislinear regressiongraphingExponentsoptimizationcalculusInterpreting GraphsFunctionsqbccCellular and Molecular BiologyChoosing modelsUnderstanding ratesConcepts in Statisticsmeasurementsmanipulating equationscreating graphsExponential and Logarithmic Functionsinterpreting tables

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    1-165-FlushToilet-ModelingScenario
    This activity analyzes the spread of a technological innovation using the Bass Model from Economics. The equation is a first-order, two-parameter separable equation and the solution has a...

    Keywords: juliaDiffusioninnovationrate of innovationBass modelSolver

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    Spreadsheet Tutorial 2 - Autofill Data, Cell References, and Standard Deviation
    Generate a table with autofill, and use absolute cell reference to calculate variance and standard deviation.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific MethodologyHigh School

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    A Direct Experience Study of Density-Dependent Growth
    An experiential approach to density-dependent growth using a checkerboard, 6-sided die, and two types of markers.

    Keywords: logistic growthdensity dependenceexperiential

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