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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Developing hands-on activities linking plankton and computational thinking
    Poster on computational thinking as a method to help address complex problems, create systems, and understand behaviors presented at the 2018 QUBES/BioQUEST Summer Workshop

    Keywords: computational thinkingplanktonSummer Workshop 2018

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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.

    Keywords: microbiologyLotka Volterrramicrobiota

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    2011-Lucas_Pulley-Analyzing Predator-Prey Models Using Systems of Ordinary Linear Differential Equations
    This research focused on applying biological mathematics to analyzing predation relationships, especially the relationship between the Canadian Lynx and the Snowshoe Hare.

    Keywords: simulationpredator-preyLotka-VolterrapopulationCanadian LynxSnowshoe Harecritical values

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    2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
    We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.

    Keywords: QUBES Leadership Teamparametersabsorptionbifurcationpharmacokineticscalciumcognitive decline

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    Supersized Life: Comparing Across Scales
    How wide is the size range of living beings, from "big" to "too small to see"? Students will collect and compare measurements from 3D specimens within the metric system by multiplying or dividing...

    Keywords: paleontologyBiodiversitytechnology in biologynatural history collectionsmiddle grades (4-9)3D models3D printingWhole Numbers & Place ValueMIDDLE SCHOOL MATH#NGSSscientific measurementscale and proportions

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    Keywords: bioinformaticsNIBLSEProtein StructureDNAmolecular modelinggenotypephenotypeCourseSourcecomputational modelingcentral dogmaplant leaf structure

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    Cell Cycle and Mitosis
    This module introduces activities that allow students to walk through the cell cycle and mitotic cell division processes. As part of the activities, students learn about and apply knowledge of...

    Keywords: introductory biologyQuantitative reasoningInterdisciplinary STEMquantitative biologyinterdisciplinaryquantitative skillscell functioncell cyclemitosisCell DivisionMitotic Indexcalculating meanstumorNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical Analysisstandard errormitotic phaseinterphase

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    Exploring the March to Mars Using 3D Print Models
    With the increased availability of 3D printers and open databases containing 3D print files, academic institutions are giving more thought into how such technology can be used in the classroom to...

    Keywords: waterMarsmicroorganismsproperties of life

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    2011-GA_Koch-Noble-Drugs in the Classroom Using Pharmacokinetics to Introduce Biomathematical Modeling
    By beginning with simple model involving the half-life of a drug, students take advantage of their mathematical abilities to explore the biology.

    Keywords: Biomathematicspharmacokinetics

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological...

    Keywords: protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular

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    A Modeling Exercise in Sexual Selection using a Student-Created Bird Species
    Evolution-centered lessons at the undergraduate level can often be jargon-heavy, propagate misconceptions if taught ineffectively, and be uninteresting to students who may not see the relevancy of...

    Keywords: Evolutionfitnesssexual selectionNatural Selectionintersexual selectionmate choice

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    CYTOSKELETON - Microtubule Dynamics in the Cell Cycle
    This module contains exercises designed to help upper-level cell biology students understand the dynamics of microtubule polymerization and depolymerization within the cell cycle and how cancer...

    Keywords: cell biologyQuantitative reasoningInterdisciplinary STEMInterpreting GraphsCytoskeletonScientific reasoningdimensional analysisNIQBC2. Data and GraphsC6. Quantitative LanguageC1. Numeracy

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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it...

    Keywords: structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate

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    Linear Regression (Excel) and Cellular Respiration for Biology, Chemistry and Mathematics
    Students typically find linear regression analysis of data sets in a biology classroom challenging. These activities could be used in a Biology, Chemistry, Mathematics, or Statistics course. The...

    Keywords: statisticsmathematicsdata analysisdatalinear regressionbiologyonlinegraphinglinear equationsQuantitative reasoningassessmentcollege algebracellstatistical analysisregressionOERAlgebrachemistryModelscorrelationSimple Linear RegressionMicrosoft Excellab activityexperimentCellular ProcessesATPqbccUsing Excelmanipulate equationsCellular and Molecular BiologyConcepts in Statisticsoxidationline of best fitexplaining statisticsusing statisticsCellular RespirationPredictionsRespirationgraphing in ExcelLinear CorrelationExothermic Reactioncreate scatter plotAdenosine Triphosphate (ATP)germinating peasPre-lab activityStudent activityHybridCollecting DataR-squareRegression ModelFunctionDependent VariablesIndependent VariablesLinear EquationLinear Equation in two variablescreate graphcreate equationcreate regressioncreate plotinterpret regressioninterpret data

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    2013-Alicia_Caldwell-Students Rise to the Challenge of Modeling Yeast Growth Despite Sour Hiccups from Imperfect Data
    This paper describes a lab in which students in an Applied Mathematics in Biology course observe the growth of Saccharomyces cerevisiae, a yeast strain, in differing sugar concentrations for use in...

    Keywords: Saccharomyces cerevisiaelogisticyeastdeathgrowthsugaralcohol

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    2008-Lawson-Marion-An Introduction to Mathematical Modelling
    This is a broad based set of notes with sections: Building Models, Studying Models, and Using Models. No depth on any model, no solution strategies, but good references to models, and general...

    Keywords: time serieslinear regressionAkaike Information Criterionmcomparision models

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    2011-Brian_Winkel-Parameter Estimates in Differential Equation Models for Population Growth
    We estimate the parameters present in several differential equation models of population growth, specifically logistic growth models and multiple species competition models.

    Keywords: logisticpopulationparameciaGausegradient search

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    BioGraphI Guidelines for Interviews - Google Docs
    This document contains step-by-step instructions used by curriculum developers to plan, conduct, and publish interviews with scientists for the Biologist and Graph Interpretation (BioGraphI)...

    Keywords: Curriculum developmentInclusive teachinginterviewRole ModelsBioGraphIBioGraphI FMNcounterstereotypical scientist

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    BioGraphI Interview Invitation (Sample Message) - Google Docs
    This document contains templates that help curriculum developers correspond with potential interviewees for the Biologist and Graph Interpretation (BioGraphI) Network. Each interview is featured in...

    Keywords: researchgraph interpretationdata literacyCurriculum developmentInclusive teachinginterviewRole ModelsBioGraphIBioGraphI FMNcounterstereotypical scientist

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    BioGraphI Considerations for Selecting a Potential Interviewee - Google Docs
    This document includes resources and advice to help curriculum developers choose a scientist to interview for the Biologist and Graph Interpretation (BioGraphI) Network. Each interview is featured...

    Keywords: researchgraph interpretationdata literacyCurriculum developmentInclusive teachinginterviewRole ModelsBioGraphIBioGraphI FMNcounterstereotypical scientist

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