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    Developing a phylogram from computational resources.
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityneighbor-joining distance matrixCourseSourcephylogrampercent identity matrix

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    1-001a-MMDeathImmigration-Variation-ModelingScenario
    We model exponential death with m&m's as well as death with immigration.

    Keywords: simulationdatam&mimmigrationdeath

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    4-039-FallingDarts-ModelingScenario
    we develop, solve, and analyze a second order differential equation model for free fall incorporating air resistance. Students solve the model using two methods -- reduction of order and...

    Keywords: optimizationresistanceterminal velocitymuzzle velocitydrag coefficientfree fallair drag

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    6-067-LotkaVolterra-ModelingScenario
    This modeling scenario guides students through the process of fitting the Lotka-Volterra model of two differential equations to a real time series observational data. Students use the capabilities...

    Keywords: time seriesdatacompetitionLotka-Volterramodel fittingpredictiongauseRexperimental

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    Making Predictions with Linear Models: A Murder Mystery Case Study
    This Swirl lesson will introduce two main concepts to students: 1) the idea of uncertainty around linear slopes versus individual values and 2) predicting values using linear models.

    Keywords: data visualizationlinear modelscase study teachinguncertaintypredictionConfidence intervals

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    Big Data, Graphs, and Prediction
    In this activity, students are introduced to graphing and modeling data in a step-wise fashion. Real data of covid-19 deaths over time are used to incrementally ask students to fit the data to...

    Keywords: epidemiologygraphingLogarithmsexponential growthqbcccovidChoosing modelsCreate graphsInterpret graphsConcepts in Statistics

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    Does Organelle Shape Matter? Exploring Cell Shape through the Allen Cell Explorer and High-content Microscopy Datasets
    The morphology and localization of structures inside the cell are often assumed to fit the ideal images found in biology textbooks. This interrupted case study using high-throughput microscopy data...
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    A Hands-on Introduction to Hidden Markov Models
    A lesson in which students will understand the basic structure of an HMM, the types of data used in ab initio gene prediction, and its consequent limitations.

    Keywords: Markov modelbioinformaticsgenomicsNIBLSEtranscriptionCourseSourceexonintronsplicing

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    Using Aquatic Macroinvertebrates in Stream Bioassessment
    Bioassessment is an evaluation of the biological condition of a waterbody using biological surveys and other direct measurements of resident living organisms. Aquatic macroinvertebrates are...

    Keywords: toleranceMacroinvertebratesRiver Field Studies Networkbioindicatorbioassessmentstream health

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    Using Place-Based Economically Relevant Organisms to Improve Student Understanding of the Roles of Carbon Dioxide, Sunlight, and Nutrients in Photosynthetic Organisms
    Biology students require broad preparation for diverse careers including agriculture, natural resource management, and laboratory research. Concurrent with this need, employers are seeking...

    Keywords: energyphotosynthesisbiomass

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    Pennies to The Moon Data Byte Series
    This series of Rbyte activities explores the concept of debunking using Fermi Estimation, R, and ChatGPT.

    Keywords: RprogrammingOpen SourceOpen Sciencedata literacycalling bullProgramming practiceFermi EstimationChatGPTGoogle CoLab

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    1999-F_Brauer-What_Goes_Up_Must_Come_Down
    It is natural to ask whether a particle propelled upwards takes longer to fall to earth from its maximum height than it takes to rise to this maximum height for frictional forces that are nonlinear...

    Keywords: resistancefallingprojectilevertical projectile

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    1-071-NewtonWatson-ModelingScenario
    Sherlock Holmes determines the time of death for a body found on a street in London and we need to reproduce his astute analysis

    Keywords: temperaturedeathNewton's Law of Coolingtime of deathSherlock Holmes

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    Oyster Restoration Success and Water Quality in the James and Rappahannock Rivers of Virginia
    This QUBES lesson uses statistical analysis to test whether or not oyster restoration sites in Virginia are successfully increasing the number of oysters and whether or not water quality is...

    Keywords: aquatic ecologymarine ecologyggplot2Pearson correlation coefficientSimple Linear RegressionnitrogenJames Rivertidyversechesapeake baywater qualityphosphorusharmful algae bloomsvirginia

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    A clicker-based case study that untangles student thinking about the processes in the central dogma
    The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students...

    Keywords: mutationtranscriptionphenotypecentral dogmatranslationDNA replication

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    2007-Mogen_Steffensen-Differential Equations in Finance and Life Insurance
    The mathematics of finance and the mathematics of life insurance were always intersecting. Life insurance contracts specify an exchange of streams of payments between the insurance company and the...

    Keywords: financedisabilitylife insurancemortalityinsuraneThiele’s equationBlack-Scholes equation

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    Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes
    Technologies like next-generation sequencing, proteomics, and high-throughput phenotyping have transformed the way we do biology. There is a continued need for scientists with computational skills...

    Keywords: computationpythonJupyter notebookFunctionscentral dogmaDictionaries

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    Microhabitats and macroinvertebrates: Logjam influences on stream morphology and macroinvertebrate traits
    Logjams are important hydrologic features that shape stream channel morphology and create habitat for organisms. In this lesson, students learn about and measure logjams in a wadeable stream and...

    Keywords: aquatic macroinvertebrateswoodriparian ecologyhabitatfunctional feeding groupRiver Field Studies Networklarge wood

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