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    1-138-InnerEarDrugDelivery-ModelingScenario
    Students examine local drug delivery to the cochlea. The delivery system is modeled as a liquid mixing problem. Students formulate the differential equation, and solve the equation using separation...

    Keywords: concentrationdrug deliveryinner earcochleahearing loss

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    Water Movement through a Membrane: The Van't Hoff Equation
    This module introduces the van't Hoff equation in the context of understanding the metabolic activity of the epithelial cells lining the stomach. It is intended for an introductory biology audience.

    Keywords: AlgebraInequalitiesCellular Processes

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    Osmosis: Determination of the rate of osmosis and the isotonic concentration
    This module contains exercises designed to help students understand how solute concentrations affect the direction and rate of osmosis. Students are given different scenarios to predict the...

    Keywords: introductory biologyQuantitative reasoninginterdisciplinarycell functionOsmosisNIQBC2. Data and GraphsC4. mathematical modelsC6. Quantitative LanguageC1. NumeracyC5. Logic and Algorithms

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    The Perfect Brew: An Activity Demonstrating Cell Counting and Hemocytometer Use
    In this activity, students will explore the use of a hemocytometer for counting cells, demonstrate the relationship between the grid seen in the microscope with volume of liquid in suspension and...

    Keywords: RatiosmicrobiologyqbccCellular and Molecular BiologyUnderstanding fractionsconverting unitschanging scalesmeasurements

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    The Perfect Brew: An Activity Demonstrating Cell Counting and Hemocytometer Use
    In this activity, students will explore the use of a hemocytometer for counting cells, demonstrate the relationship between the grid seen in the microscope with volume of liquid in suspension and...

    Keywords: RatiosmicrobiologyqbccCellular and Molecular BiologyUnderstanding fractionsconverting unitschanging scalesmeasurements

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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    Michaelis-Menten Enzyme Kinetics
    In this simulation, equations used in enzyme kinetics (Michaelis-Menten, Eadie-Hofstee, Dixon, and Lineweaver-Burk) are modeled under various conditions.

    Keywords: ExcelResources @ ESTEEMMichaelis-Mentenenzymesenzyme kinetics

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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.

    Keywords: absorptioncompartmentbloodstreamplasmapharmacokineticsdrugpharmacodynamics

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    2014-Blomhøj-EtAl-Compartment models
    An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a...

    Keywords: concentrationkineticsphysiologycompartmentsalttankbalancereactionsminkbathtub

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    1-094-SteepingTea-ModelingScenario
    We provide photographs of steeping process for a tea steeped in hot water. Students build a differential equation model for the steeping process and do parameter estimation using the color of our...

    Keywords: concentrationSurface AreacolorNewton's Law of Coolingteasugar

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    5-030-AirshedSulphur-ModelingScenario
    Temperature inversions and low wind speeds trap air pollutants in a mountain valley for a period of time. Gaseous sulfur compounds are a significant air pollution problem. We offer a model for...

    Keywords: sulphurpollutionairshedhydrogen sulfidesulfur dioxide

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    Making Predictions with Linear Models: A Murder Mystery Case Study
    This Swirl lesson will introduce two main concepts to students: 1) the idea of uncertainty around linear slopes versus individual values and 2) predicting values using linear models.

    Keywords: data visualizationlinear modelscase study teachinguncertaintypredictionConfidence intervals

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    Discrete Math Modeling with Biological Applications (Course Materials)
    These are the materials for Math 214 offered at Rhodes College.

    Keywords: labsagent-based modelingDiscrete Difference Equationsmatrix modelscoursebiomath coursedemonstrationin-class activitylab protocolproblem set

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    Cellular Respiration and pH: blocking the electron transport chain and its effects on the proton gradient, pH, and ATP production
    This module contains exercises designed to help students describe the stages of cellular respiration and quantify the energy molecules produced. Students will predict the region of higher proton...

    Keywords: introductory biologyQuantitative reasoningquantitative biologyinterdisciplarycell functionInterpreting GraphsATPpHCellular RespirationEnergy transformationsElectron flowNIQBC2. Data and GraphsC4. mathematical modelsC1. Numeracyproton gradientelectron transportelectron transport blockersFADH2chemiosmosisATP synthaseNADHproton concentration

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    Grow the Gradient: An interactive countercurrent multiplier game
    The countercurrent multiplier of the loop of Henle in a mammalian kidney is a challenging concept for instructors to teach and for students to learn. We developed an interactive game to support...

    Keywords: countercurrent multiplierexcretory systemkidneyloop of Henlemembrane transport

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    Learn Biological Sciences and Physics through scientific process, creation, experimentation and analysis
    Microbes remain attached and grow on various surfaces whether living or non-living. These surfaces provide differential growth substances for microbes to remain attached or grow. The differential...

    Keywords: data analysisscientific methodphysicshands-onScientific InquirymicrobesBiological SciencesSpectrophotometer

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    Using the Project Eddie Module “Paleoclimate and Ocean Biogeochemistry” in the Upper-Division Undergraduate Course “Climate and the Earth System”
    Students explore and compare datasets on modern nutrient concentrations and productivity, as well as paleo datasets to try to answer the question: “How does primary productivity influence global...

    Keywords: BiogeochemistryPaleoclimatepleoceanographygeochemistry

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    2004-Ledzewicz-Schattler-Application of Control Theory in Modelling Cancer Chemotherapy
    In this paper we discuss how to incorporate more realistic medical aspects of chemotherapy which hitherto have been neglected in the models.

    Keywords: optimal controldrug resistancepharmacokineticspharmacodynamicschemotherapy

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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.

    Keywords: liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model

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    Water Quality Module (Project EDDIE)
    Students utilize real-time nitrate data from the US Geological Survey to statistically evaluate water quality impacts and to identify their causes

    Keywords: dataconcentrationProject EDDIEnnitrogen cycle

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