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    Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy
    Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and...

    Keywords: bioinformaticsDNA sequenceRNAseqgene expression

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    Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection
    In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection...

    Keywords: cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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    Learning about Protein Structure and Function with Molecular CaseNet
    Poster on the case studies available through Molecular CaseNet that focus on protein structure and function. Presented at the 2021 BIOME Institute.

    Keywords: case studiesmolecular biologyProtein Structureprotein function2021 BIOME

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    Advanced Student Molecular Case Study Authorship Scaffolded Project and Rubric
    Instructions, assignment prompts, and a rubric for assessing advanced undergraduate authorship of molecular case studies
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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    1998

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    2015-Liang-EtAl-Advanced ordinary differential equation based head modelling for Chinese marionette art preservation
    This paper addresses the heritage preservation of the marionette head carving by digitalizing the head models with a novel modelling technique using ordinary differential equations (ODEs).

    Keywords: digitizationcontrolmarionetteChinese marionettehead carving

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    LearnR Apps
    Presentation on using the LearnR software in teaching. Presented at the 2021 BIOME Institute

    Keywords: mathematicsRStudioformulascomputer programming2021 BIOMEparson's problems

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    Bioinformatics is a BLAST: Engaging First-Year Biology Students on Campus Biodiversity Using DNA Barcoding
    In order to introduce students to the concept of molecular diversity, we developed a short, engaging online lesson using basic bioinformatics techniques. Students were introduced to basic...

    Keywords: geneticsorganismal biologybioinformaticstaxonomyDNA Barcodingspecies concepts

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience...

    Keywords: EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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    To Vaccinate or Not to Vaccinate
    To vaccinate or not to vaccinate, that is the question. Much of the recent trend in society against vaccination is that the general population does not understand 1) how vaccines work and 2) how...

    Keywords: pathogenELISAimmunityantibodyAntigen

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    2018-LA_Peletier-Ordinary Differential Equations in Pharmacodynamics
    Good mix of theory, application, solution technique in a number of areas of applications of differential equations. Develops qualitative behavior issues. Exercises, but not about models, more about...

    Keywords: compartment modelpharmacokineticspharmacodynamicsorbitsturnover

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    2015-Beckmann-Sanchez-Cache Calculus-Modeling Caches through Differential Equations
    We present cache calculus, a technique that models cache behavior as a system of ordinary differential equations, letting standard calculus techniques find simple and accurate solutions of cache...

    Keywords: discretecachecache calculus

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    5-010-MatrixExponential-TechniqueNarrative
    The matrix exponential is a powerful computational and conceptual tool for analyzing systems of linear, constant coefficient, ordinary differential equations (ODE's). This narrative offers a quick...

    Keywords: matrix esponentialPutzer's Algorithmdiagonalizationeigenvalueseigenvectors

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    Gelin’: Gel Electrophoresis Simulation
    Students will understand how DNA is separated into a fingerprint by using a chromatography activity to simulate gel electrophoresis.

    Keywords: DNAgel electrophoresisdna fingerprintchromatography

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    Maria vs Malaria
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.

    Keywords: bioinformaticsmolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    Morphological and Molecular Analysis of Plant Phylogeny and Diversity
    In this lab, students perform phylogenetic analyses on morphological and molecular data, and compare.

    Keywords: morphologyphylogenylaboratoryplantsdiversitymolecular analysis

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    Phylogenetic analysis using collections material: interpreting trait evolution by comparison of morphological and molecular genetic hypotheses
    Exercise spans two weeks, includes homework, and involves some groups of animals as well as plants. Emphasizes re-interpretation of morphological trait evolution following molecular genetic...

    Keywords: Evolutionmorphologyphylogenylaboratoryplantsbiological collectionsmolecular analysis

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    Morphological and Molecular Analysis of Plant Phylogeny and Diversity
    In this lab, students perform phylogenetic analyses on morphological and molecular data, and compare.

    Keywords: morphologyphylogenylaboratoryplantsmolecular analysis

    2007

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