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    Enzymes and the Rate of Chemical Reactions
    This module introduces rates of reactions in the context of understanding how enzymes affect chemical reactions. It is intended for an introductory biology audience.

    Keywords: calculushyperbolic equationsCellular Processesrates of change

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    Data from: Advancing population ecology with integral projection models: a practical guide
    Review important resources for building IPMs and provide a comprehensive guide, with extensive R code, for their construction.

    Keywords: IPMintegral projection modelsdemographyelasticitylife historymatrix projection modelpopulation growth ratepopulation projection modelsensitivitystage structurevital ratesResources @ DryadResources @ QUBES - Data

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    1989-EY_Rodin-K_Egan-Mathematics modelling of the rate of chemical reactions
    The development of improved designs for chemical reactors as well as the prediction of optimal operating conditions in chemical production are based on an understanding of the rates at which...

    Keywords: kineticsfirst orderreactionsecond orderzeroth order

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    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    Global Dietary Habits in Relation to Adult Obesity
    With global obesity rates continually increasing, an analysis of the relationship between dietary patterns and global obesity rates was performed with datasets representing sugar consumption,...

    Keywords: dietglobal healthObesity

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    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving...

    Keywords: stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates

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    1-041-AirToTop-ModelingScenario
    One common rule taught to SCUBA divers is to ascend no faster than thirty feet per minute. In this project we will examine safe variable ascent rates, time required for a safe ascent using variable...

    Keywords: SCUBAascentair managementbreathingdivingunderwater

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    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.

    Keywords: experimental designsystems biologyAssociation & Data Fittingreaction ratesdecay rates

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    Diseasebots
    This module explores the effects of host density on contact rates and transmission of pathogens or mutualist symbionts using a hands-on simulation, a computer agent-based model in NetLogo, and an...

    Keywords: NetLogoDisease ecologydensity dependenceSpreadsheethost-parasitemutualismOpen-inquiry group projectsmanipulative models (‘beanbag biology’)plotting

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    Transpiration
    In this lab, students will examine differences between C3 and C4 plants in their transpiration rates.

    Keywords: plant physiologybotanylaboratoryResource Type

    1970

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    495

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    Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms
    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...

    Keywords: mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

    1947

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    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer...

    Keywords: cancertumorfittingagent-based

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    2009-Peter-Howard-Modeling With ODE
    This is a set of class notes rich in examples and ideas for modeling. There is some MatLab code in support of some of the activities.

    Keywords: ratescompetitionpopulationepidemicpendulumcarbon datingreaction chemistrymechanicsplanetary motiondrag racingHamilton’s methodvariational method

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    Aquatic Macroinvertebrates and Urbanization: Exploring urbanization’s effect on leaf litter decomposition in six streams of Puerto Rico using R
    Urbanization effects stream ecosystems by introducing pollutants to the streams.. This has detrimental effects on the life of the streams such as the aquatic macroinvertebrates who are in charge of...

    Keywords: aquatic macroinvertebratesStream ecologyurbanizationsurban runoff

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    Plate Tectonics: GPS Data, Boundary Zones, and Earthquake Hazards (Project EDDIE)
    Students work with high precision GPS data to explore how motion near a plate boundary is distributed over a larger region and hypothesize the area over which boundary-related earthquake hazards...
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    Diffusion Through a Cell Membrane
    This module introduces rates of diffusion in the context of understanding simple and facilitated diffusion through the cell membrane. It is intended for an introductory biology audience.

    Keywords: linear equationscalculushyperbolic equationsCellular Processesrates of change

    950

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    Quantitative Cytological Characteristics: Photorespiration
    This module introduces quantitative cytological characteristics in the context of understanding cell behavior under stress. It is intended for an introductory biology audience.

    Keywords: plant physiologyRatioschart

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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    Bioimage Informatics Activity
    Students use basic bioimage informatics techniques to acquire quantitative data from images of cultured cells and test a hypothesis about the effect of a genetic mutation on cellular phenotypes

    Keywords: geneticsResources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

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