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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Teaching the Photoelectric Effect Using an Open-Source Interactive Simulation
    The photoelectric effect is one of the fundamental experiments that established the basis of quantum mechanics. Students studying this experiment in modern physics courses struggle to understand...

    Keywords: photoelectric effectquantum mechanicsquantalight-matter interactions

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    Design Your Own Flow Cytometry Experiment: A Four-Week Inquiry Laboratory
    Due to its importance to the field, flow cytometry should be one of the hallmark methods a student learns in the lab portion of an undergraduate immunology course. Flow cytometry is a classic lab...

    Keywords: Immunologyexperimental designFlow cytometryMice

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    BioVEDA Curriculum: An Approach to Link Conceptual and Quantitative Understanding of Variation During Experimental Design and Data Analysis
    When performing a biological investigation, experts constantly cycle between conceptual and quantitative modes of thinking, integrating their understanding in both worlds to make decisions about...

    Keywords: statisticssample sizeBiological variation

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    Antibiotic Resistance Genes Detection in Environmental Samples
    Our aim is to provide an authentic research experience for undergraduate students in a variety of biology courses through collaboration between a four-year university and a community college. This...

    Keywords: geneticsenvironmentmicrobiologyUndergraduateantibiotic-resistancePCRgel electrophoresisauthentic inquiry

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    Escape Zoom!: Reviewing Introductory Evolution Content Using an Escape Room Format
    Reviewing and integrating key concepts and learning goals at the end of a biology course can be overwhelming to students and instructors alike. Often end-of-term review sessions in preparation for...

    Keywords: Evolutionartificial selectionSpeciationextinctionsexual selectionphylogenetic treesmechanisms of evolution

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    Soil Respiration Module (Project EDDIE)
    Soils hold more carbon (C) than any other component of the terrestrial biosphere!

    Keywords: Project EDDIE

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    Stream Discharge Module (Project EDDIE)
    Stream discharge is a fundamental measure of water supply in stream systems. Low discharge may cause problems with water supply and fish passage, while high discharge may mean flooding. In this...

    Keywords: floodsProject EDDIEurbanizationstreams

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    Amino Acid Frequency
    This module introduces expected frequencies in the context of understanding amino acid composition. It is intended for an introductory biology audience.

    Keywords: Probabilitylinear regressionamino acidsOpenStaxGenetic InformationAminoAmino Acid Freuency

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    Mutation and Selection: An Exploration of Antibiotic Resistance in Serratia Marcescens
    This laboratory module gives students hands-on experience with mutation and selection in bacteria.

    Keywords: moduleinquiry labsmutationartificial selectionbacteriain-class activityHandoutlab protocolResources @ QUBES - Teaching & Referenceantibiotic-resistance

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    Claymander Field Experiment
    This activity addresses how predation may affect the frequency of two color morphs in a population. Students collect and analyze data from clay salamander models ('claymanders') to determine...

    Keywords: Field researchpredation ecologysalamanderAudience level - Introductory UG - majorsAudience level - Advanced UG

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    Teacher Guide: Math and Statistics
    Topics include measures of average (mean, median, and mode), variability (range and standard deviation), uncertainty (standard error and 95% confidence interval), Chi-square analysis, student...

    Keywords: Resources @ HHMI - BioInteractiveStatistics and Mathteacher guide

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    Coral Bleaching Mapping Activity
    This is a classroom activity in which students use authentic data to assess the threat of coral bleaching around the world. It supports the 2014 Holiday Lectures on Science video featuring Dr....

    Keywords: ecologyResources @ HHMI - BioInteractiveBiodiversityclimateScientific ProcessStatistics and Mathecosystemsearth and environmenthuman impactsHigh School

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    QUBES: a community focused on supporting teaching and learning in quantitative biology
    This letter provides an overview of the Quantitative Undergraduate Biology Education and Synthesis (QUBES) Project funded through the National Science Foundation.

    Keywords: mathematicseducationQUBESprofessional developmentbiologycollaborationproceedings

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    The Science Behind the ACTN3 Polymorphism
    A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has...

    Keywords: protein structure and functionhuman genetic variationskeletal muscle physiology

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    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving...

    Keywords: stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates

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    Measuring Size and Area of Digitized Specimens using ImageJ
    Use ImageJ to analyze morphological characters in digital images of natural history specimens. Skills are transferable to many organisms and other morphological measurements.

    Keywords: ImageJnatural history collectionscourse-based research experiences (CUREs)digitized natural history collections

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    Hypoxia: A Case Study in R
    Aquatic ecosystems are home to a complex intersection of physical and biological factors and an intersection of natural and anthropogenic factors. In the Chesapeake Bay, low oxygen events have...

    Keywords: data analysisOceanographyProject EDDIE

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    Traditional Ecological Knowledge and Natural History
    In this module, students will explore Western Science and Traditional Ecological Knowledge and review a case study of how the TEK of the Inuit provided a way of knowing and understanding the...

    Keywords: Traditional ecological knowledgeUnderstanding ScienceBowhead Whale

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    Amphibian Diversity: Species Richness and Precipitation
    This activity will explore how natural history specimen data can be used to investigate the relationship between precipitation levels in a region and species diversity of amphibians.

    Keywords: data in the classroomBiodiversitytrade-offsnatural history collectionAmphibans and Reptiles

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    2015-Boggess-EtAl-Mathematical Modeling in Ecology - Simulating the Reintroduction of the Extinct Passenger Pigeon
    To determine under which conditions a Passenger Pigeon could survive a reintroduction into a natural habitat, we used two types of models.

    Keywords: simulationagent-based modelingallee_effectPassenger Pigeonsforest envirnomentHolling Type III functional responseBio-energeticstree distributions

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