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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?
    One of the challenges of teaching Cell Biology is helping students understand important research methods used to study cells.  The goal of understanding cell biology methods is especially...

    Keywords: ABC transporter familyDifferential centrifugationImmunoblottingImmunofluorescence assayProtein localizationPurifying organellesSDS-PAGE

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams....

    Keywords: image analysismicroscopymitosisCellular Processes

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    2007-Choisy-Guégan-Rohani-Mathematical Modeling of Infectious Diseases Dynamics
    After presenting general notions of mathematical modeling (Section 22.2) and the nature of epidemiological data available to the modeler (Section 22.3), we detail the very basic SIR epidemiological...

    Keywords: stochasticSIR modeldeterministicincubationinfectives

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    Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory
    The COVID-19 pandemic has forced much university instruction into virtual modes. As a result, many laboratory courses have either dropped content altogether or replaced hands-on activities with...

    Keywords: protein structure and functionProtein sequenceintermolecular forcesBiomacromolecules

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    Bio 18: Statistics for Scientific Data Analysis
    Poster on the a data science course presented at the 2019 BioQUEST & QUBES Summer Workshop
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    A Hands-on Introduction to Hidden Markov Models
    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM...

    Keywords: transcriptionexonintronsplicing

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    Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology
    The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module,...

    Keywords: mutationtranscriptiongene expressioncentral dogmatranslationgel electrophoresisGenotype/Phenotype

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    Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
    Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This...

    Keywords: SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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    Wind and Ocean Ecosystems (Project EDDIE)- adapted to provide greater autonomy for students in an upper level class
    This module adaption focuses on the interplay between winds, ocean upwelling, and marine productivity. Students are able to select and download their own data and compare results among different...
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    PhyloCards: a fun approach to exploring the local Wissahickon biodiversity, Chestnut Hill, Philadelphia, PA
    PhyloCards are educational trading cards that teach people about biodiversity, conservation, and ecosystem relationships. We used this educational tool to explore the Wissahickon Valley's...

    Keywords: species richnessPokemon Gobiodiversity literacytrophic chain

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    The Challenge of Food
    How will we feed the estimated 9 billion people that will be on the planet by 2050? How can food be distributed equally? We’ll hear about making more nutritious food via genetic engineering and...

    Keywords: videosScience ForwardfoodGMOs

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    Summer 2019 Biobytes
    This series includes the four Biobytes that were piloted at the 2019 BioQUEST / QUBES Summer Workshop titled, “Evolution of Data in the Classroom: From Data to Data Science”.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab
    This hands-on, student-centered biochemistry lesson introduces beginner biochemistry students to the techniques of effectively reading and discussing primary literature, identifying fundamental...

    Keywords: primary literatureexperimentationyeastMetabolismFermentationRespirationequilibrium

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    Introduction to Earth Data Science Textbook
    Introduction to Earth Data Science is an online textbook for anyone new to open reproducible science and the Python programming language. There are no prerequisites for this material, and no prior...

    Keywords: data analysisdatadata typesdata visualizationdata scienceearth sciencepythonremote sensingGeographic Information System (GIS)data science educationcomputer programmingwildfireearth analytics

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    Teaching epidemiology and principles of infectious disease using popular media and the case of Typhoid Mary
    Allied health students often struggle to understand how particular content, such as epidemiology, connects to their future careers. This activity uses the case of Typhoid Mary as a foundation for...

    Keywords: epidemiologycase studyinfectous diseasepopular mediaTyphoid Mary

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    Plasmodium Problem Space
    This problem space brings together diverse resources with the goal of helping biology teachers and learners engage in research investigations.

    Keywords: bioinformaticsproblem spacesNIBLSERNAseqmalariaplasmodium

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    Teaching the Photoelectric Effect Using an Open-Source Interactive Simulation
    The photoelectric effect is one of the fundamental experiments that established the basis of quantum mechanics. Students studying this experiment in modern physics courses struggle to understand...

    Keywords: photoelectric effectquantum mechanicsquantalight-matter interactions

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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    Inclusive Pedagogy for Life Science Education Tagging Ontology
    Inclusive Pedagogy for Life Science Education Tagging Ontology

    Keywords: ontology

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