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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    2020-Chen_Et_Al-MathModel_Simulation_Phase-Based_Transmissability_Corona_Virus
    In this study, we developed a Bats-Hosts-Reservoir-People transmission network model for simulating the potential transmission from the infection source (probably be bats) to the human infection.

    Keywords: basic reproduction numbercoronavirusnext generation matrixtransmissibilitynovel coronavirus

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    Using Bioinformatics Activities to understand the Past and Present of SARS-CoV2
    We have designed a Bioinformatics activity that uses tools to identify the origins and mutations in the novel SARS-CoV2 strains.
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    2020-Ciaroshi-How_COVID-19_Spreads_MathModels
    On December 31, 2019, the Chinese city of Wuhan reported an outbreak of a novel coronavirus (COVID-19) that has since killed over 4,200 people. As of March 11, 2020, over 118,000 infections—have...

    Keywords: diseasecovidoutbreakWuhancoronoavirus

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    Drugging SARS-CoV-2
    This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

    Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

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    Introduction to nucleotide sequence analysis and protein modeling in MEGA and PyMol using coronavirus SARS-CoV-2
    Introduction into computational approaches in phylogeny and protein modeling based on coronavirus SARS-CoV-2 (caused COVID-19 pandemic). Two self-guided tutorials for standard lab classes of 2.5...

    Keywords: phylogeneticsundergraduate educationbioinformaticsNCBICOVID19coronavirusMEGAPyMolvirtual labPDBprotein modelingSARSSARS-CoV

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    Let's Talk About COVID-19
    This exercise asks you to write a short paper reflecting on your personal experiences (or those you have read about) with COVID-19
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    Coronavirus Epidemic Curves - Graphically Interpreting Derivatives
    A set of exam questions or class activity related to 'flatten the curve' during the coronavirus outbreak of 2020. Content includes: notation, first derivative, second derivative, and interpreting...

    Keywords: derivativescalculussecond derivativefirst derivativeInterpreting GraphsCOVID19coronavirus

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    Social Distancing Simulation in NetLogo
    A NetLogo simulation that shows the effects of social distancing on the spread of infectious disease.
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    6-016-PandemicModeling-ModelingScenario
    The recent coronavirus outbreak has infected millions of people worldwide and spread to over 200 countries. How can we use differential equations to study the spread of coronavirus?

    Keywords: population dynamicsinfectious diseasediseaseEbolaeSIR modelsCOVID19pandemicepidemicreproduction number

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    COVID-19 Simulator (ISEE) Module
    This accessible module guides students through exploring the COVID-19 Simulator developed by ISEE. Students dig into the four scenarios provided (including the parameters and the graphs),...

    Keywords: mathematical modelingSTELLAInfectious Disease ModelingInterpreting Graphsinterpreting modelsCOVID19coronavirus

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    QUBES: Building a community to promote undergraduate quantitative biology education
    QUBES is designed to improve communication among educators, assist faculty in understanding and implementing novel content and teaching strategies in their classrooms, and create an academic reward...

    Keywords: QUBES

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    A Potential Novel Ecosystem Service: Seagrass Meadows Reduce Disease in Nearby Corals
    In this lesson, students will receive an introduction to Poisson Generalized Linear Mixed Models in R utilizing data on coral diseases. In their code, students will assess if seagrass status has an...

    Keywords: environmental scienceseagrassecosystemcoral reefsEcosystem Services

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    SEIR simulation activity for flattening the curve
    This is a short exploration activity to introduce SIR and SEIR models without explicitly introducing differential equations. It utilizes the R package EpiDynamics and students can run the...

    Keywords: RRStudioInfectious Disease ModelingSIR modelsSIRseircovidcoronavirus

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    Reading and Discussing Popular Media to Increase SEA-PHAGES Student Engagement
    This module introduces ways for students to connect their SEA-PHAGES work and real life medical trials with events presented in Arrowsmith, Sinclair Lewis’s 1925 Pulitzer prize winning novel on...

    Keywords: discussionsbacteriophagereadingSEA-PHAGESpopular media

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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    COVID-19: Molecular Basis of Infection
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    Statistics with epidemiology of COVID-19
    Introduction into heat maps, non-parametric t-test and GIF (optional) in R using an original dataset on COVID-19 infections from different counties of New Jersey, USA. Suitable for students who...

    Keywords: Rundergraduate educationheat mapsCOVID19coronavirusSARS-CoV-2GIF

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    Self-Assembling Geometric Solids Videos
    An online resource showcasing research and developments in self-assembling 3D printed models. Our collection of videos covers various aspects of the self-assembly process and novel techniques.

    Keywords: GeometricSelf-assemblysolidsPlatonicArchimedean

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    2015-Liang-EtAl-Advanced ordinary differential equation based head modelling for Chinese marionette art preservation
    This paper addresses the heritage preservation of the marionette head carving by digitalizing the head models with a novel modelling technique using ordinary differential equations (ODEs).

    Keywords: digitizationcontrolmarionetteChinese marionettehead carving

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