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    Electron Location, Location, Location: Understanding Biological Interactions
    Introductory Biology courses typically introduce the structure and function of biomolecules such as proteins and nucleic acids. To understand biomolecules fully, students require knowledge of...

    Keywords: hydrogen bondshydrophobicity/hydrophilicitypolar and non-polar covalent bonds

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    Using Phyre2
    How to use Phrye2 and 3DLigandSite to computationally predict protein and active site structure and binding partners (substrates/cofactors/coenzymes).

    Keywords: videosbioinformaticsproteinsgenomicsyoutubephyre23DLigandSite

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    The Avocado Lab: An Inquiry-Driven Exploration of an Enzymatic Browning Reaction
    Typical biochemistry labs exploring basic enzyme activity rely on costly, time-consuming protein purification and rarely explore enzyme function in situ. Further, complex purification procedures...

    Keywords: enzymescontrolsenzyme inhibition

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    Hemoglobin Evolution
    This module introduces equations describing blood viscosity and oxygen transport in the context of understanding the evolution of red blood cells. It is intended for an introductory biology audience.

    Keywords: calculushyperbolic equationsAnimal Physiologyparabolic equationsmaxima

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    Lung Capacity and Rhythms in Breathing
    This module introduces rhythmic inhaling and exhaling in the context of understanding trigonometry and sine waves. It is intended for an introductory biology audience.

    Keywords: Trigonometrysine wavesAnimal Physiology

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    Learn Biological Sciences and Mathematics through cellular respiration, photosynthesis and primary productivity.
    Photosynthesis is a process by which plants synthesize glucose and oxygen in presence of sunlight through light dependent reactions by utilization of sunlight, water to synthesize oxygen, ATP and...

    Keywords: mathematicssimulationThe Analysis of Biological DataMetabolic Pathwaysprocess of sciencephotosynthesisqbccBiological ScienceshypothesisCellular Respirationprimary productivity

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    2004-Mitchell-von Meien-Krieger-Dalsenter-A review of recent developments in modeling of microbial growth kinetics
    Mathematical models are important tools for optimizing the design and operation of solid-state fermentation (SSF) bioreactors. Such models must describe the kinetics of microbial growth.

    Keywords: Filamentous Fungisolid-state fermentationgrowth kineticsdiffusion-reactionoxygen transfer

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    Hypoxia: A Case Study in R
    Aquatic ecosystems are home to a complex intersection of physical and biological factors and an intersection of natural and anthropogenic factors. In the Chesapeake Bay, low oxygen events have...

    Keywords: data analysisOceanographyProject EDDIE

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    Amphibian Diversity: Species Richness and Precipitation
    This activity will explore how natural history specimen data can be used to investigate the relationship between precipitation levels in a region and species diversity of amphibians.

    Keywords: data in the classroomBiodiversitytrade-offsnatural history collectionAmphibans and Reptiles

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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    Taking the Hassle out of Hasselbalch
    Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the...

    Keywords: pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa

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    Hypoxia in Coastal Marine Ecosystems (Project Eddie) - Modified
    Aquatic ecosystems are home to a complex intersection of physical and biological factors and an intersection of natural and anthropogenic factors. In the Chesapeake Bay, low oxygen events have...

    Keywords: OceanographyProject EDDIEEutrophication

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    Hypoxia in Coastal Marine Ecosystems (Project Eddie)
    Aquatic ecosystems are home to a complex intersection of physical and biological factors and an intersection of natural and anthropogenic factors. In the Chesapeake Bay, low oxygen events have...

    Keywords: OceanographyProject EDDIEEutrophication

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    Maria vs Malaria - AR Adaptation
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

    Keywords: bioinformaticsAugmented RealityLarge class sizemolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    Using the Project Eddie Module “Paleoclimate and Ocean Biogeochemistry” in the Upper-Division Undergraduate Course “Climate and the Earth System”
    Students explore and compare datasets on modern nutrient concentrations and productivity, as well as paleo datasets to try to answer the question: “How does primary productivity influence global...

    Keywords: BiogeochemistryPaleoclimatepleoceanographygeochemistry

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    Lake Mixing Module (Project EDDIE)
    Students explore spatial and temporal patterns of lake mixing using high-frequency temperature data from lakes around the world.

    Keywords: stratificationProject EDDIE

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    Efficiency of ATP Prodution
    This module introduces the efficiency of ATP production in the context of understanding glycolysis and endergonic reactions. It is intended for an introductory biology audience.

    Keywords: RatiosOpenStaxCellular ProcessesEndergonic ReactionsATPGlycolysis

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs...

    Keywords: fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills

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    Drugging SARS-CoV-2
    This case study leads students through the process of proposing a drug for a novel protein. The Mpro protease of SARS-CoV-2 is explored in detail within the PDB. Aligns with first semester...

    Keywords: viruscoronavirusPDBSARS-CoV-2proteasedrug design

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