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    Luria-Delbruck
    These two workbooks model the evolution of phage resistance in a bacterial population under two alternative hypotheses.

    Keywords: phageLuria-Delbruckresistance

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    Writing Microbiology Resource Announcements (MRA)
    This resources provides a framework for students to write a Microbiology Resource Announcement, collaboratively.

    Keywords: phageBioinformatics and GenomicsGenome announcementmanuscriptMRA

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    Genome Solver - A bioinformatics pipeline for community science
    The Genome Solver was an NSF-funded project developed as a way to train undergraduate life science faculty in basic web-based tools for bioinformatics. As part of the project we developed a one-day...

    Keywords: phylogeneticsbacteriophagebacteriaHorizontal Gene transferGenome Analysis

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    How to Find a Gene: Retrieving Information From Gene Databases
    A strong understanding of distinct gene components and the ability to retrieve relevant information from gene databases are necessary to answer a diverse set of biological questions. However, often...

    Keywords: NCBItranscriptiontranslationGene StructureGene databasesEnsembl

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    Hands-On, Hands-Off: The Community College Genomics (ComGen) Course-Based Undergraduate Research Experience
    Science is a process of discovery where failure is inherent and iteration is necessary, yet instructors often teach the scientific process as if it is a controlled, highly supervised, confirmatory...

    Keywords: geneticssequencingDNAbacterium

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    Lesson VI - The Community Science Project
    Genome Solver's Community Science Project was developed as a way to use the skills taught in the previous lessons. We're asking members of the community to provide instances of potential phage...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Reading and Discussing Popular Media to Increase SEA-PHAGES Student Engagement
    This module introduces ways for students to connect their SEA-PHAGES work and real life medical trials with events presented in Arrowsmith, Sinclair Lewis’s 1925 Pulitzer prize winning novel on...

    Keywords: discussionsbacteriophagereadingSEA-PHAGESpopular media

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    1-150-CancerTherapy-ModelingScenario
    This activity builds upon elementary models on population growth. In particular, we compare two different treatment models of cancer therapy where in one, surgery happens before therapy and in the...

    Keywords: population dynamicsphage therapyexponential growthcancerwater treatmentdecaysurgery

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    Understanding Restriction Enzyme Digests
    Prior to submitting genomic DNA for sequencing, SEA students perform a restriction endonuclease digest with several enzymes, which provides a fast and cost-effective way of quickly screening...
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    Phage Comparative Genomics Lab Manual
    A lab manual containing detailed instructions for several bioinformatics tools (dot plots, Phamerator maps, phylogenetic trees, and gene content similarity), all of which enable students to perform...

    Keywords: phageCUREcourse-based research experiences (CUREs)Comparative genomicsSEA-PHAGES

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    Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages
    The goal of this lesson is to introduce students to the lytic and lysogenic cycles of T4 and lambda bacteriophages, respectively, using student-centered pedagogies. Bacteriophages are viruses that...

    Keywords: bacteriophagesLysogenic cycleLysogenyLytic cycle

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    Understanding Host-Pathogen Interactions With the Use of Galleria mellonella
    The Galleria mellonella; the larvae of the Greater Wax Moth, is a safe and effective means to study host-pathogen interactions in the undergraduate setting. The use of animal models in the teaching...

    Keywords: innate immunitybacterial pathogenesisHost-pathogen interactionsGalleria mellonellaVirulence

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    Data Analysis Recitation Activities Support Better Understanding in SEA-PHAGES CURE
    Course-based undergraduate research experiences (CUREs) are widely known to improve student learning outcomes in the sciences. Undergraduate students have a particularly difficult time interpreting...

    Keywords: bacteriophageDNA extractionGel analysisPhage purificationTiter calculationViral replicative growth

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    You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”
    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented...

    Keywords: bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

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    Laboratory Math
    Explanations and demonstrations on how to use mathematical equations for various laboratory purposes, including those specific to SEA-PHAGES (such as phage titer calculations) and those that are...
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    Using Dotplots for Comparative Genomic Analysis
    In this activity, students are introduced to dotplots as a tool for analyzing phage genomic similarity.
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    Introduction to Phylogenetic Trees for Comparative Genomic Analysis
    In this activity, students are introduced to phylogenetic trees and networks as tools for analyzing evolutionary relationships.
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    Introducing PHAGES Students to Primary Literature
    The ‘Introducing PHAGES Students to Primary Literature’ set of teaching resources offers faculty 2 distinct sets of teaching resources for introducing students to scientific literature in the...
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    Exploring Functions for Common Phage Proteins
    This resource is designed to help students better understand the functions of common structural and enzymatic phage proteins, and to relate these functions to phage structure using electron...
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    Student and Faculty Tools for Generating High-Quality Phage Annotations
    Phage genome annotation requires collaboration between faculty and their student research team. This set of resources provides tools to assist both students and faculty in the evaluation and...
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