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    Genome Solver: Complete Set of Lessons
    The Genome Solver Project began as a way to teach faculty some basic skills in bioinformatics - no coding or scripting. These Lessons also work well in the undergraduate classroom, culminating...

    Keywords: bioinformaticsNIBLSEBioinformatics EducationBioinformatics and GenomicsC4. Bioinformatics toolsC5. Data retrievalC6. ModelsC8. Data typesC9. ImplicationsRecommended by NIBLSE

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    Using DNA Subway to Analyze Sequence Relationships
    This is a bioinformatics exercise using the DNA Subway Blue Line, a user-friendly pipeline of bioinformatics tools, to analyze a collection of mosquito DNA bar-code sequences.

    Keywords: phylogeneticsNIBLSEDNA BarcodingDNA sequenceBLASTmultiple sequence alignmentC1. Role of bioinformaticsC2. Computational conceptsC4. Bioinformatics toolsC5. Data retrievalC8. Data typesIncubated at NIBLSE

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    Intro to DNA Subway Blue Line
    This is a classroom tested introductory lesson & activity to introduce DNA Barcoding and DNA Subway Blue Line. It is for novices and will fit into a 1 hr 50 min lecture or lab class period.

    Keywords: phylogeneticsNIBLSEDNA BarcodingDNA sequenceBLASTmultiple sequence alignment

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    Monkey Opsins
    This case will examine the evolution of trichromatic vision in old world monkeys.

    Keywords: modulephylogeneticsecologycell biologymolecular geneticsResources @ EvoEd

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    Case Study: Genetic Variation and Speciation in the Black Tailed Rattlesnake complex (Crotalus molossus)
    It is important for biology students to understand how genetic variation is related to the formation of species in nature. This module is intended for students to obtain first hand experience with...

    Keywords: phylogeneticscase studySpeciationtree readingsystematicsTree thinkingPhylogeographydistance learninggenetic variation

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    A Phylogenetic Analysis of the Evolution of the CRYAA Gene Across Vertebrates
    Although the divergence of the aA-crystallin protein from other heat shock proteins has been examined, the extent to which the CRYAA gene controlling it has evolved across vertebrate species...

    Keywords: phylogeneticsvertebrates

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    What’s the DEAL – The Digital Encyclopedia of Ancient Life and Digital Atlas Apps
    The Digital Encyclopedia of Ancient Life and Digital Atlas Apps -- identify fossils and explore diversity and history of life on earth.

    Keywords: phylogeneticsdigital resourcesfossilspaleontologyevolutionary biologytaxonomyeduappsnatural history collections3D modelsgeologyopen textbookdigitized natural history collectionsencyclopediaatlasCretaceous World TCNPaleo Niches TCNvirtual teaching collectionFossil field guide

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    Inquiry-based hypothesis testing using phylogenetic trees in MEGA
    A key learning objective in biology is applying bioinformatics tools to test a real-life question. These inquiry-based modules have students assemble and align data, and construct simple...

    Keywords: phylogeneticsbioinformaticsFASTANCBIBLASTmultiple sequence alignmentsequence similarityCourseSourceZika virusMEGAalcohol metabolism

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    When did I lose my legs? A limbless lizard tale
    Using oVERT project models students examine examples of extant traditional lizards, snakes and limbless lizards and create phylogenies based on trait and genetic data.

    Keywords: phylogeneticsevolutionary biologyHerpetologynatural history collections3D models#NGSSdigitized natural history collectionsoVertConvergent Evolution

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    Vertebrate Clade Race
    This activity introduces basic tree reading skills for evolutionary phylogenies. It is designed as a short group activity. After completing this activity, students should be familiar with basic...

    Keywords: phylogeneticsevolutionary biologytree readingvertebrates

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    One species, two species, red species, lead species? Phylogenetics and species concepts with Plethodon salamanders
    This lab introduces students to species concepts and basic computer-based tree-building methods using published nuclear and mitochondrial sequence data for Plethodon salamanders.

    Keywords: phylogenetic analysisTree thinkingsalamanderAudience level - Advanced UG

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    Applying phylogenetic tree building in MEGA X to forensic applications for identifying unknown specimens
    This exercise is designed to guide a learner through the construction of phylogenetic trees as a means of addressing research questions in forensic science such as the identification of previously...

    Keywords: taxonomyBioinformatics and GenomicsDNA Barcodinginvertebrate phylogeneticsforensic entomology

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    Genome Solver - A bioinformatics pipeline for community science
    The Genome Solver was an NSF-funded project developed as a way to train undergraduate life science faculty in basic web-based tools for bioinformatics. As part of the project we developed a one-day...

    Keywords: phylogeneticsbacteriophagebacteriaHorizontal Gene transferGenome Analysis

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    The Tactile Clade Race
    This adaptation of the Vertebrate Clade Race provides a tactile approach to introduce basic tree reading skills for evolutionary phylogenies. Using a Universal Design for Learning informed...

    Keywords: phylogeneticsevolutionary biologytree readingvertebratesaccessibility for students with disabilities or impairmentsvisual impairment

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    Sequence Similarity: Introducing Biological Databases to Community College Biology Students
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    Developing a phylogram from computational resources.
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityneighbor-joining distance matrixCourseSourcephylogrampercent identity matrix

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    Bioinformatics: Investigating Sequence Similarity - A Plant Biology Approach
    This laboratory module is a modification of the original published on CourseSource with a focus on plant biology. In the final activity, students conduct a BLAST to compare histone protein...

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBIplant biologyNIBLSEalgorithmsincubatorsPlant and Fungal EvolutionBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogram

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    E. coli Citrate Use
    EvoEd module on citrate use in E.coli

    Keywords: modulephylogeneticsecologycell biologymolecular genetics

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    Using the Hardy-Weinberg Equations: Quantifying Natural Selection and Allele Frequencies
    This module contains exercises designed to walk students through a real-world example of the coevolution of fruit color and primate frugivore color vision. Students will apply the Hardy-Weinberg...

    Keywords: Hardy-WeinbergEvolutionintroductory biologyQuantitative reasoninginterdisciplinaryNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical AnalysisC6. Quantitative LanguageC1. Numeracy

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