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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Using the Cell Engineer/Detective Approach to Explore Cell Structure and Function
    As instructors of introductory biology courses for majors and non-majors, we have struggled with teaching the concept of cell structure and function in an engaging way.  However, this is a...

    Keywords: cell functionCell StructureCellular diversityDynamic cellular functionOrganelle function

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    Life in Urban Environments: The Impact of Urbanization on Life-History Traits in Amphibian Species
    This lesson focuses on urbanization and its negative effects on species, specifically amphibians. The lesson will also provide hands-on statistical analyses and critical thinking questions to...

    Keywords: life historyRStudiofrogstwo-way ANOVAurbanizationamphibianstoads

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    Development of the NIBLSE Learning Resource Collection and Incubators
    Talk on the NIBLSE Resource Collection and Incubators given at several professional development confernces

    Keywords: bioinformaticsNIBLSEincubators

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    2007-Ramsay-Hooker-Campbell-Cao-Parameter estimation for differential equations-a generalized smoothing approach
    We propose a new method for estimating parameters in models that are defined by a system of non-linear differential equations.

    Keywords: estimating equationfunctional data analysisGauss–Newton methodparameter cascadeprofiled estimationdynamic system

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    3-064-GearTrain-ModelingScenario
    Students model an input-output mechanical system of gears with a second order, non-homogeneous, ordinary differential equation with constant coefficients. The model incorporates friction and...

    Keywords: frictiongearspur geargear traintorquegear ratioangular accelerationangular velocitymoment of inertiadouble reduction gear

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Lesson on what it means for biological processes to be Poissonian, published in CourseSource

    Keywords: quantitative biologybioinformaticsmicrobiologyphysicsNIBLSEHIVCourseSourcemultiplicity of infectionPoisson Distribution

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    Introduction to Genome Browser: What is a Gene?
    In this module, we will use a web-based visualization tool called a Genome Browser to explore the structure of a eukaryotic gene, and obtain a basic understanding of how this information is...
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    Integration of Bioinformatics into Life Science Curricula: Community Development, Dissemination, and Assessment of a NIBLSE Learning Resource
    Big data and computational tools have transformed the way we address biological questions. To prepare undergraduates for tomorrow’s challenges, life science curricula should integrate the...

    Keywords: bioinformaticsNIBLSELife Science

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    Glycolysis Can Be Fun: Rediscovering Glycolysis as a Problem-Solving Introduction to Metabolism
    A thorough understanding of glycolysis forms a foundation for students to analyze subsequent topics in metabolism, a core competency recognized by multiple national societies for biology and...

    Keywords: Problem based learningPOGILenzymesGlycolysisMetabolismFermentationchemical reactionsCard sorting activityCofactors

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    Half Life of mRNA
    This module introduces exponential growth and decay in the context of understanding the stability of mRNA. It is intended for an introductory biology audience.

    Keywords: exponential equationsGenetic Informationlogarithmic equationshalf-lifemRNA

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    2019-Stender_EtAl-Recovery_Of_Differential_Equations_From_Impulse_Response
    In this work, a recent method, which allows reconstructing differential equations from time series data, is extended for higher degrees of automation.

    Keywords: time seriesregressionresponseimpulseoscillationsignal processingsparse regressionsystem identification

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    Serenity now! Keep calm and do science with real data in the classroom
    Presentation on a free web application currently under development on QUBES called Serenity at the 5th Life Discovery Conference

    Keywords: data sciencetool:serenity5th Life Discovery- Doing Science Education conference (LDC)5th Life Discovery Conference

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    2017-Alex_Honchar-Neural Networks For Solving Differential Equations
    In this post I want to show how I applied simple feed-forward NNs to different differential equations with increasing complexity: ODEs, second order ODEs, and, finally, PDEs.

    Keywords: neural networksCybenko theoremdiffusion equationfluid dynamics

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    Simulating Cortical Rotation, Axis Induction, and Experimental Embryology in Amphibian Embryos Using Clay Models
    The study of development requires learners to understand spatially complex concepts like embryo anatomy. Embryo anatomy is dynamic over time, and it is often manipulated by researchers in...

    Keywords: developmentXenopusfertilizationEmbryologyinductionSymmetry breakingOrganizerCortical rotationPatterning

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    The Case of the Missing Strawberries: RFLP analysis
    While solving the fictional mystery of the missing strawberries, students are engaged in a guided-inquiry lesson featuring small-group and class discussions, hands-on activities, and laboratory...

    Keywords: process of scienceDNAforensicsgel electrophoresisMolecular genotypingRestriction endonucleaseRestriction enzymeRestriction fragment length polymorphismRFLP

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    Population Demography in Swirl
    The students will learn to generate, test, and graphically represent basic hypotheses on data distributions using large datasets.

    Keywords: ecologyPopulation statisticslife history curves

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    Biodiversity, Big Data, and the Fossil Record
    In this lab, we will be making and testing hypotheses about how the biodiversity of groups of organisms may vary through time.

    Keywords: digital resourcesnatural history museumspaleobiology

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    Fitting Exponential and Logistic Growth Models to Bacterial Cell Count Data
    In this activity, students will model a noisy set of bacterial cell count data using both exponential and logistic growth models. For each model the students will plot the data (or a linear...

    Keywords: modelingdata analysislinear regressiongraphingExponentsoptimizationcalculusInterpreting GraphsFunctionsqbccCellular and Molecular BiologyChoosing modelsUnderstanding ratesConcepts in Statisticsmeasurementsmanipulating equationscreating graphsExponential and Logarithmic Functionsinterpreting tables

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    Agent-Based Modeling Course Materials
    Materials created for an upper level ABM course. Prerequisite: Students have taken either (a) another modeling course, or (b) the introductory computer science sequence.

    Keywords: agent-based modelingindividual-based modelingcourse materials

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    Incubators: Building community networks and developing open educational resources to integrate bioinformatics into life sciences education
    To efficiently and effectively integrate bioinformatics instruction into undergraduate life science curricula, educators would benefit from open access, high-quality learning resources (LRs) for...

    Keywords: bioinformaticsNIBLSEincubatorsLife Science

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