You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    A Case of Severe Insulin Resistance
    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistance

    1399

    views

    558

    downloads

    0

    comments

    1

    adaptations

    Climate Change Effects on Lake Temperatures (Project EDDIE)
    Students explore new modeling and computing tools while learning fundamental concepts about how climate change will affect lakes

    Keywords: climate changeProject EDDIElakes

    1162

    views

    321

    downloads

    0

    comments

    0

    adaptations

    It's a Substrate... It's a Protein...No - It's an Enzyme! Teaching Using 3D Serine Protease Physical Modeling Activities to Confront Misconceptions.
    Reported misconceptions of enzyme-substrate interactions highlight the necessity for better, targeted instructional tools and assessments. A series of active learning activities with corresponding...

    Keywords: Protein StructureEnzymes-Substrate InteractionsNoncovalent InteractionsGeometric ComplementaryElectronicsStereochemistrySerine Proteases

    2853

    views

    367

    downloads

    0

    comments

    0

    adaptations

    Augmented Reality Metabolic Pathways (ARMET)
    The ARMET app is developed using Unity, 3D molecules obtained from Protein Data Bank and ChemSpider-chemical structure database, the usage data are stored into a database (MySQL) and are analyzed...

    Keywords: BiochemistryAugmented RealityMetabolic Pathways

    1222

    views

    318

    downloads

    0

    comments

    0

    adaptations

    Waking up Anna - Adaptations and Conversion to Mol*
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment. The adaptations addressed question clarity and reformatting to use Mol*.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABAMolCaseNetMol*MolStarProtein visualizationFlumazenil

    925

    views

    1545

    downloads

    0

    comments

    0

    adaptations

    A flexible, multi-week approach to plant biology - How will plants respond to higher levels of CO2?
    To help introductory biology students understand how plants will respond to higher levels of CO2, we have created a multi-week module consisting of a series of four related laboratory lessons....

    Keywords: statisticsplantsphotosynthesiscarbon dioxidecommunicating sciencegroup workResource AllocationRespirationStomata

    18562

    views

    380

    downloads

    0

    comments

    0

    adaptations

    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing...

    Keywords: genomicstranscriptionsignaling

    7602

    views

    362

    downloads

    0

    comments

    0

    adaptations

    Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory
    The COVID-19 pandemic has forced much university instruction into virtual modes. As a result, many laboratory courses have either dropped content altogether or replaced hands-on activities with...

    Keywords: protein structure and functionProtein sequenceintermolecular forcesBiomacromolecules

    2130

    views

    194

    downloads

    0

    comments

    0

    adaptations

    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

    2496

    views

    736

    downloads

    0

    comments

    0

    adaptations

    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    Keywords: transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

    4536

    views

    1087

    downloads

    1

    comments

    0

    adaptations

    5-040-TunedMassDampers-PartII-ModelingScenario
    Studentsbuild mathematical models to mitigate dangerous swaying in structures using structural improvements called Tuned Mass Dampers (TMD). We model the motion of the original structure as a...

    Keywords: structureresistancespring-mass-dashpotearthquakevibrationcontroldampingtuned mass damperstiffnessreduction of vibration

    274

    views

    265

    downloads

    0

    comments

    0

    adaptations

    Build-a-Phage Lab Manual
    This is a lab manual for phage genome synthesis that includes both Building Block synthesis and Semi-synthetic assembly.
    1350

    views

    657

    downloads

    0

    comments

    0

    adaptations

    Amino Acid Frequency
    This module introduces expected frequencies in the context of understanding amino acid composition. It is intended for an introductory biology audience.

    Keywords: Probabilitylinear regressionamino acidsOpenStaxGenetic InformationAminoAmino Acid Freuency

    1722

    views

    504

    downloads

    0

    comments

    0

    adaptations

    Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?
    One of the challenges of teaching Cell Biology is helping students understand important research methods used to study cells.  The goal of understanding cell biology methods is especially...

    Keywords: ABC transporter familyDifferential centrifugationImmunoblottingImmunofluorescence assayProtein localizationPurifying organellesSDS-PAGE

    1420

    views

    508

    downloads

    0

    comments

    0

    adaptations

    2017-Bonin-EtAl-Mathematical modeling based on ordinary differential equations - promising approach to vaccinology
    As a proof of concept, we developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data...

    Keywords: immune systemyellow fevercomputational immunologycomputational vaccinology

    116

    views

    42

    downloads

    0

    comments

    0

    adaptations

    2016-Bonin-EtAl-Mathematical modeling based on ordinary differential equations-vaccinology
    We developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.

    Keywords: Immunologyimmune systemAntigenvaccinologyyellow fever

    120

    views

    63

    downloads

    0

    comments

    0

    adaptations

    Cross-Scale Interactions (Project EDDIE)
    Students explore new modeling and computing tools while learning fundamental concepts about how lake phytoplankton blooms occur through cross-scale interactions.

    Keywords: modelingProject EDDIE

    1132

    views

    278

    downloads

    0

    comments

    0

    adaptations

    Integrating Manipulatives and Animations to Visualize Holliday Junctions
    The complex molecular architecture of Holliday junctions is often challenging for undergraduate biochemistry students to conceptualize. In particular, they have difficulty translating from...

    Keywords: dna structureDNA damageDNA recombinationGene crossoverHolliday junction

    1884

    views

    365

    downloads

    0

    comments

    0

    adaptations

    5-040-TunedMassDamper-Part-I-Modeling Scenario
    We offer an opportunity to build mathematical models to mitigate dangerous displacements in structures using structural improvements called Tuned Mass Dampers. We model the motion of the original...

    Keywords: structurespring-mass-dashpotspring massearthquakevibrationtuned mass tunerrestoring forcecontroldampe

    437

    views

    985

    downloads

    0

    comments

    0

    adaptations

    The Mystery of the Missing Martens
    National Center for Case Study Teaching in Science- this interrupted case study introduces basic modeling to investigate a decline in an American marten population on an island in Southeast Alaska.

    Keywords: modelingsurvivaldata analysisvital ratessurvivorshippopulation ecologyage structurefecundityWildlife Biologymodellingmartensbirth ratelife table

    1668

    views

    327

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search