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    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer...

    Keywords: cancertumorfittingagent-based

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    2014-Enderling-Chaplain-Mathematical Modeling of Tumor Growth and Treatment
    Herein we describe fundamentals of mathematical modeling of tumor growth and tumor-host interactions, and summarize some of the seminal and most prominent approaches.

    Keywords: cancertumor modelingangiogenesistumor growthpatient care

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    RAT ATTACK! Population growth
    This module contains exercises focused on the use and interpretation of density independent and density dependent population growth models. Students build logistic and exponential growth models in...

    Keywords: modelingecologyExcelintroductory biologygraphingQuantitative reasoningdata visualizationinterdisciplinaryexponential growthlogistic growthdata managementInterpreting Graphspopulation modelingNIQBC2. Data and GraphsC4. mathematical modelsnonlinear models

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    2011-Teleken-EtAl-Mathematical modeling of microbial growth in milk
    A mathematical model to predict microbial growth in milk was developed and analyzed. The model consists of a system of two differential equations of first order. The equations are based on physical...

    Keywords: bacteriadairymilkfood safetymicrobilogy

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    2007-Zenker-Rubin-Clermont-From inverse problems in mathematical physiology to quantitative differential diagnoses
    The improved capacity to acquire quantitative data in a clinical setting has generally failed to improve outcomes in acutely ill patients, suggesting a need for advances in computer-supported data...

    Keywords: physiologyinverse problem

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    1-125-DiceyPopulation-ModelingScenario
    We offer students an opportunity to generate data for their team on a death and immigration model using 12 and 20 sided dice and then pass on the data to another student team for analysis with a...

    Keywords: simulationimmigrationdeathdice

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    1-025-MixingItUp-ModelingScenario
    Students build three different models for levels of salt in a tank of water and at each stage the level of complexity increases with attention to nuances necessary for success.

    Keywords: compartmentsalttankmixing

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    2004-Hill-Lozowski-Sampson-Experiments on ice spikes and a simple growth model
    We observed ice-spike growth using time-lapse digital photography, using two water types in two different containers.

    Keywords: iceice spikebulk heat transfermass conservation

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    2003-Richard-Carson-Tracer kinetic modeling in PET
    The use of radiopharmaceuticals and the imaging of their biodistribution and kinetics with modern instrumentation are key components to successful developments in PET.

    Keywords: Metabolismtomographyradiopharmaceuticalspositron emission

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    2003-Knorrenschild-Gross-Text Books on Mathematical Modeling in Biology
    Text Books on Mathematical Modeling in Biology Compiled from the Internet by Michael Knorrenschild,

    Keywords: biologyMathematical Biologytextbooktext

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.

    Keywords: spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions

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    A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity
    The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of...

    Keywords: Diffusionsolubilitycovalent bondshydrophilichydrophobicpartition coefficientplasma membranepolarity

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    Making “sense” out of surface area to volume relationships
    Using a multimodal approach, the non-linear aspect of the surface area to volume relationship is explored. Students use their their senses of taste and sight to determine how smaller cells and...

    Keywords: active learningintroductory biologycell biologyquantitative skillskinesthetic learningLDC2023

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    2012-Greer-Palin-Students in Differential Equations and Epidemiology Model a Campus Outbreak of pH1N1
    We describe a semester-long collaboration between a mathematics class and a biology class. Students worked together to understand and model the trajectory of the pandemic H1N1, pH1N1, outbreak...

    Keywords: H1N1pandemicspreadoutbreakpH1N1

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    Learning R for Biologists: A Mini Course Grab-Bag for Instructors
    As biology becomes more data driven, teaching students data literacy skills has become central to biology curriculum. Despite a wealth of online resources that teach researchers how to use R, there...

    Keywords: Rdata analysisRStudio

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    Teaching biostatistics using the Rule of Four
    A guide to helping intro bio students develop a deeper understanding of key statistical concepts by translating among numeric, graphical, verbal, and symbolic representations.

    Keywords: statisticsbiostatisticsintroductory biologyQuantitative reasoningBIOME 2022

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    2007-John_Jungck-Ten_Equations_that_Changed_Biology-Mathematics_in_Problem-Solving_Biology_Curricula The author
    These equations were selected upon the basis of wide-spread recognition of the value of the models.

    Keywords: biologyequationsten equations

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological...

    Keywords: protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular

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    1-035-DotseroVolcanoEruption-ModelingScenario
    In this scenario, we use Carbon-14 dating of the Dotsero volcano in Colorado as a way of emphasizing this multistage process of modeling.

    Keywords: exponential decayhalf-lifedecayEuler's methodcarbon datingdecay rateCarbon-14Dotsero volcanovolcano

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    Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab
    This hands-on, student-centered biochemistry lesson introduces beginner biochemistry students to the techniques of effectively reading and discussing primary literature, identifying fundamental...

    Keywords: primary literatureexperimentationyeastMetabolismFermentationRespirationequilibrium

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