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    2016-Wilkie-EtAl-Using ODEs to Explore Cancer-Immune Dynamics and Tumor Dormancy
    Here we present a general method using ordinary differential equations (ODEs) to model and analyze cancer-immune interactions, and in particular, immune-induced tumor dormancy.

    Keywords: cancertumor-inhibiting cytotoxic actiontumor-promoting inflammationimmune-induced tumor dormancytumor growth dynamics

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    2001-Smith-Moore-The SIR Model for Spread of Disease
    A multiple part tour of SIR Models freely available with Maple, Mathematics, and MatLab support files at MAA site.

    Keywords: epidemicSIR modelEuler's methodherd immunityHong Kong flu

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    1987-Claude-Marmasse-Studies on differential equations of enzyme kinetics-Biomolecular scheme
    The integral curve is compared with the solutions given by the two classical approximations to the problem: it is shown that the steady-state approximation is to be preferred to the rapid...

    Keywords: steady-state modelisoclinesenzyme kinetics

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    2-001-NumericalMethodsComparisons-TechniqueNarrative
    This material teaches the basics of numerical methods for first order differential equations by following graphical and numerical approaches. We discuss the order of accuracy of the methods and...

    Keywords: Euler's methodimproved Euler's methodRK3 methodsRK4 methodsorder of accuracyabsolute errorCPU time

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    1-002-IntegratingFactor-TechniqueNarrative
    We develop a strategy to solve first order differential equations by transforming one side of the equation to the derivative of a product of two functions, thereby making it easy to...

    Keywords: Integrating Factor

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    Using Case Studies to Engage Students in Wicked Problems
    Interactive presentation on using case studies at the 2018 QUBES/BioQUEST Summer Workshop

    Keywords: case studiesSummer Workshop 2018wicked problems

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression.  This laboratory lesson allows students...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    Venom: To Kill or Cure?
    In this case study, students will explore concepts of evolution, protein structure and function, taxonomy, and methods of scientific inquiry in a real-world way.

    Keywords: EvolutionphylogeneticsidigbioAP Biologytaxonomynatural history collections3D modelsoVertVenomsnakesherps

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    AIM-UP! Reading scientific literature module
    Designed to span 4 one-hour lectures, this module focuses upon developing the skill of thorough and critical reading of scientific literature.

    Keywords: Resources @ AIM-UP!primary literaturereadingscientific literatureliteraturereading comprehensioncritical reading

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    Interconnections in The Open Ecosystem
    Presentation on open education and open science given as the keynote address at the 2019 BioQUEST & QUBES Summer Workshop

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    What is Science?
    This video has a philosophical focus and explores the nature of science. We’ll hear about how science is both a body of knowledge and a process. Peer review and confirmation bias will also be covered.

    Keywords: videosStudent misconceptionsScience Forwardscience basics

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    Using Yeast to Make Scientists: A Six-Week Student-Driven Research Project for the Cell Biology Laboratory
    Traditionally-trained undergraduate students often lack an understanding of science as an active process that yields the information presented in their textbooks. One result has been a call for...

    Keywords: yeastgrowth curvecell proliferationviability

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    Pick Your Poison: A Semester-Long Case Study for Undergraduate Toxicology
    The ability to collate information from diverse scientific resources and effectively employ scientific writing is an essential skill for scientists. This lesson describes a semester-long project...

    Keywords: risk assessmenttoxicologyPharmacologyregulationsdose responseADME

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    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing...

    Keywords: genomicstranscriptionsignaling

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    Spreadsheet Tutorial 5: Histogram
    Generate a histogram using a variety of methods.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific MethodologyHigh School

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    Spreadsheet Tutorial 4: t-Test
    Calculate t-values and perform t-tests using built-in functions.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific Methodology

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    Spreadsheet Tutorial 3 - Column Graphs, Error Bars, and Standard Error of the Mean
    Generate a column or bar graph with standard error bars.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific MethodologyHigh School

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    Spreadsheet Tutorial 2 - Autofill Data, Cell References, and Standard Deviation
    Generate a table with autofill, and use absolute cell reference to calculate variance and standard deviation.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific MethodologyHigh School

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    Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms
    Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as...

    Keywords: statisticsLabCUREInquiryresearch skillscaterpillardaphniadrugsscience process

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    Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes
    This case study engages students in generating hypotheses and predictions, analyzing and interpreting data, critically evaluating contrasting results in science, and thinking about feedbacks...

    Keywords: population biologycarbon cyclingSpecies-habitat interactions

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