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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    Incorporating authentic research experiences into undergraduate labs, while shown to be particularly effective at engaging and retaining students in STEM majors, can be difficult to accomplish...

    Keywords: gene regulationmicroRNAsgene expression

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    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of...

    Keywords: cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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    Teaching RNAseq at Undergraduate Institutions: A tutorial and R package from the Genome Consortium for Active Teaching
    Next-generation sequencing is radically changing the study of biology, but there are currently few resources aimed at teaching the required laboratory and data-analysis skills to undergraduate...

    Keywords: statisticsbioinformaticsRNAseqgene expressioncomputer programming

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    You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”
    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented...

    Keywords: bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

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    Using Pathway Maps to Link Concepts, Peer Review, Primary Literature Searches and Data Assessment in Large Enrollment Classes: An example from teaching ecosystem ecology
    As with many other complex topics, teaching ecosystem ecology can be particularly difficult in terms of helping students understand the relationships between the various component parts. We...

    Keywords: energyecosystemNutrientsPathway

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    The Case of the Missing Strawberries: RFLP analysis
    While solving the fictional mystery of the missing strawberries, students are engaged in a guided-inquiry lesson featuring small-group and class discussions, hands-on activities, and laboratory...

    Keywords: process of scienceDNAforensicsgel electrophoresisMolecular genotypingRestriction endonucleaseRestriction enzymeRestriction fragment length polymorphismRFLP

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    Sex-specific differences in Meiosis: Real-world applications
    In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam.  The rapid explosion of available scientific facts in recent...

    Keywords: meiosisReproductionAneuploidyGameteNon-disjunctionOocyteSpermTrisomy

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    Modeling the Research Process: Authentic human physiology research in a large non-majors course
    Laboratory experiences in large-enrollment introductory science courses often utilize “cookie-cutter style” laboratory experiences due to the relative simplicity of setting up the lab...

    Keywords: data analysishypothesis testingexperimental designphysiology

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    Plotting Cranial and Spinal Nerve Pathways in a Human Anatomy Lab
    Hands-on experiences with cadavers, animal dissections, or plastic models are effective at improving student learning and attitudes in human anatomy courses. The hands-on experience allows students...

    Keywords: human anatomyNervous systemBrainCranial nerveNerveSpinal cordSpinal nerve

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    Constructing a robust understanding of homologous chromosomes, sex chromosomes, and the particulate nature of genes is a notoriously difficult task for undergraduate biology students. In this...

    Keywords: bioinformaticsautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

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    Does it pose a threat? Investigating the impact of Bt corn on monarch butterflies
    Aspiring scientists know that a hallmark of science is that experiments are repeatable and testable.  However, students do not often get opportunities to explore the replicability of...

    Keywords: ecologyCommunity EcologyBt cornGenetic modificationMonarch butterflies

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    Coevolution or not? Crossbills, squirrels and pinecones
    This case reinforces the concept of coevolution as a reciprocal change in genetic structure between or among two or more populations, by having students analyze and interpret data, build a...

    Keywords: fitnessCoevolutionCo-adaptation

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    Bad Cell Reception? Using a cell part activity to help students appreciate cell biology, with an improved data plan and no loss in coverage
    With a veritable myriad of cell parts to cover, it is easy for educators to become locked into marathon presentations that become taxing for both the instructor and the students. While we hope and...

    Keywords: primary literatureprokaryotesCell partsEukaryotesOrganelle functionOrganelles

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    Why Meiosis Matters: The case of the fatherless snake
    A compelling reason to learn something can make all the difference in students’ motivation to learn it.  Motivation, in turn, is one of the key attitudes that drives learning.  This story...

    Keywords: meiosismitosissex determinationAsexual reproductionParthenogenesis

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    Urban stream invaders: a scientist spotlight featuring Dr. Piatã Santana Marques
    Students read and interpret data from a study which addresses how urbanization affects the invasive attributes of a non-native species. They also reflect on the identity of the lead researcher and...

    Keywords: ecologyInvasive SpeciesStream ecologyurban ecologynutrient pollution

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    Wind and Ocean Ecosystems (Project EDDIE)- adapted to provide greater autonomy for students in an upper level class
    This module adaption focuses on the interplay between winds, ocean upwelling, and marine productivity. Students are able to select and download their own data and compare results among different...
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    Science of Sorting
    Children possess an innate curiosity about the natural world. This Discovery Trunk explores the topic of sorting, or classification, in the study of life science.

    Keywords: species interactionsphylogenyscience educationPropertytaxonomyindividual traitsLife ScienceSortOrganizationReproductionclassifycharacteriesticlivingnonlivingobjectsadvantagedichotomous keyliving systemsoffspringphysical traitbehavioral traitcladecladogramtaxonomistnatural worldkingdomsbinomial nominclatureone class periodgradesK-8K-8

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    Wind and Ocean Ecosystems (Project EDDIE)
    This module introduces students to the concepts of Ekman transport, eastern boundary currents, and upwelling, while learning how to find a location on a map using latitude and longitude, how to...
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    “Leveling Up” In Your Favorite Video Game Math Modeling Activity
    Students write linear equations that represent their model for solving a problem about playing video games.

    Keywords: modelingNIMBioslinear equationsmiddle grades (4-9)Middle SchoolSystems of Equations

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    Food, Energy and Water Learning Modules (FEWLM) Workbooks
    FEWLM is a low-cost inquiry-based interdisciplinary STEM prototypical curriculum built on Next Generation Science Standards, systems thinking and informed engineering design pedagogy.

    Keywords: K-12inquiry-based learningNext Generation Science StandardsSystem Thinking

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