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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Healing the scars: Tropical rainforest carbon cycling. Does it matter which tree species you plant?
    This online module explores how differences in traits of tropical tree species translate into differential effects on the carbon cycle, integrating ecological information across scales and the...

    Keywords: climate changecarbon cyclingtropical biology4DEE Frameworkforest restorationtropical tree speciessoil carbon

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    Furry with a chance of evolution: Exploring genetic drift with tuco-tucos
    Genetic drift is an important mechanism of evolution, yet undergraduates often fail to understand how it leads to evolutionary change due in part to its random nature. This lesson plan describes a...

    Keywords: EvolutionGenetic DriftBottle neckFounder effectRandom evolutionary processes

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    SIMIODE Spring 2024 Webinars - Insightmaker
    We discuss the use of the FREE system dynamics software Insightmaker (https://insightmaker.com/) in a first course in Ordinary Differential Equations (with a modeling emphasis).

    Keywords: modelingsimulationSoftwarepythonsystemsInsightMakerflowCategory Theorystockstock-flow

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    2015-Boggess-EtAl-Mathematical Modeling in Ecology - Simulating the Reintroduction of the Extinct Passenger Pigeon
    To determine under which conditions a Passenger Pigeon could survive a reintroduction into a natural habitat, we used two types of models.

    Keywords: simulationagent-based modelingallee_effectPassenger Pigeonsforest envirnomentHolling Type III functional responseBio-energeticstree distributions

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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric...

    Keywords: pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy

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    2013-Deboeck-Bergeman-The reservoir model-DE model of psychological regulation
    The following article describes a differential equation model based on the concept of a reservoir for psychological regulation.

    Keywords: adaptive copingReservoirsNotre Dame Longitudinal Study on Agingoutputinput distributionstressorscoping resources

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    2012-Nokkaew-EtAl-Estimation of Algae Growth Model Parameters by a Double Layer Genetic Algorithm
    This paper presents a double layer genetic algorithm (DLGA) to improve performance of the information-constrained parameter estimations.

    Keywords: optimizationalgae growthgenetic algorithmssimulated dataconvergence of parameters

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    2009-James_May-Nonlinear vibration control of long flexible structures
    An automated, non-linear control scheme was developed to transfer energy from the fundamental vibration mode, where most vibration energy of the structures of interest resides, to higher order...

    Keywords: vibrationdampingtuned mass damperviscousnodalmodel dampingflexible structureenergy transfer

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    2008-Huet-Deffuant-Differential Equation Models Derived from an Individual-Based Model Can Help to Understand Emergent Effects
    We study a model of primacy effect on individual's attitude. Typically, when receiving a strong negative feature first, the individual keeps a negative attitude whatever the number of moderate...

    Keywords: agent-based modelprimacy effectinformation filteringaggregated modelcollectiveinteractionsdouble-modelling

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological...

    Keywords: protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular

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    2019-Banuelos_Danet_Flores_Ramos-Epidemiological_Math_Model_Approach_To_Political_System_with_Three_Parties
    A nonlinear compartmental model is derived to study the movement between classes of voters with the assumption of a constant population that is homogeneously mixed.

    Keywords: politicsparametersvotingcompartment modelepidemiological modelequilibriathree-party system

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    Choose Your Own Adventure: Control a Wildlife Disease Epidemic
    This educational game allows teams of students to try to control a simulated epidemic in United States snake populations using their epidemiological and ecological knowledge. It combines a "choose...

    Keywords: educational game

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    1-096-OP-AMP-Differentiator-ModelingScenario
    The output waveform (function) of a operational amplifier type of differentiator circuit is determined analytically from the first order governing ordinary differential equation and compared with...

    Keywords: simulationMeasurementfeedbackMultisimcircuitvoltageoperational amplifiervalidationSPICE

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    Joel E. Greengiant Learns About Peas: From Nucleotides to Selection
    This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet (wrinkled) peas, all in...

    Keywords: geneticspopulation geneticsEvolutionintroductory biologycase studybiologyResources @ NSF - NCCSTSmeiosisMendel’s peaspea plantPisum sativumMendel’s Lawsmolecular geneticsmutationnucleotide insertionartificial selectionstarch synthesisstarch branching enzymeplant domesticationlegumesResources @ QUBES - Teaching & Reference

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    Diseasebots
    This module explores the effects of host density on contact rates and transmission of pathogens or mutualist symbionts using a hands-on simulation, a computer agent-based model in NetLogo, and an...

    Keywords: NetLogoDisease ecologydensity dependenceSpreadsheethost-parasitemutualismOpen-inquiry group projectsmanipulative models (‘beanbag biology’)plotting

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Introductory physics courses are required for many programs in the life sciences, yet traditional curricula fail to help students meaningfully connect physical concepts with biological...

    Keywords: quantitative biologyHIVmultiplicity of infectionPoisson DistributionPhysics for biologists

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    The Impact of Diet and Antibiotics on the Gut Microbiome: Distance Education Variant
    The goal of this article is to describe a variation of an active learning exercise that was previously published by the same author under a similar title. The variation describes modifications...

    Keywords: microbiomenutritionbacterial metabolitesgut bacteriahost response

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    Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation
    Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is...

    Keywords: gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)

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    Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems
    In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based...

    Keywords: modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning

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    The impact of diet and antibiotics on the gut microbiome
    The goal of this article is to describe an active learning exercise that can be used in a variety of advanced microbiology courses, including bacterial physiology, ecology, or systems biology. The...

    Keywords: microbiomeenvironmental controlhost responsemetabolites

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