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    Using the Cell Engineer/Detective Approach to Explore Cell Structure and Function
    As instructors of introductory biology courses for majors and non-majors, we have struggled with teaching the concept of cell structure and function in an engaging way.  However, this is a...

    Keywords: cell functionCell StructureCellular diversityDynamic cellular functionOrganelle function

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    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of...

    Keywords: cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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    Modeling the lac Operon to Understand the Regulation of Gene Expression in Prokaryotes
    This resource is a recitation activity designed for an introductory biology course in which students explore a lac operon simulation (https://qubeshub.org/resources/phetlacoperon).

    Keywords: simulationLac Operon

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    More In Depth Spreadsheet Management Adaptation of Data Management using NEON Small Mammal Data
    This adaptation consists of three exercises that introduce students to 1) format spreadsheet data tables, 2) carry out spreadsheet quality control, and 3) count/sort/filter data of interest in...

    Keywords: data managementspreadsheetsmammalsCapture mark-recapture

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    Glycolysis Can Be Fun: Rediscovering Glycolysis as a Problem-Solving Introduction to Metabolism
    A thorough understanding of glycolysis forms a foundation for students to analyze subsequent topics in metabolism, a core competency recognized by multiple national societies for biology and...

    Keywords: Problem based learningPOGILenzymesGlycolysisMetabolismFermentationchemical reactionsCard sorting activityCofactors

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    The Polar Bear of the Salt Marsh? Warming Tolerance Limits of Local Species
    National Center for Case Study Teaching in Science- In the adaptation exercise, students explore connections between saltmarsh sparrow declines and declining populations of local species that live...

    Keywords: Coastal wetlandsConnecticutmanagementnortheastsea-level risesalt marsh

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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it...

    Keywords: structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate

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    Defining and Understanding Pathogenic Disease: An Engaging Activity that Connects Students' Lived Experiences with their Academic Studies
    Contagious diseases are unavoidable realities of life. Thus, understanding pathogens and their respective diseases is important in many biological subfields including evolution, ecology, health...

    Keywords: infectious diseasePathogenspathogenic disease

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    Tying it All Together: An Activity to Help Students Connect Course Experiences to Posted Learning Outcomes
    Instructors of undergraduate courses in Biology and other Science, Technology, Engineering, and Mathematics (STEM) disciplines face an ongoing challenge to foster higher-order thinking and learning...

    Keywords: metacognitionreflectiongoalsOutcomes

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    Ecology of Infectious Disease: Data Mining the National Notifiable Diseases Surveillance System (NNDSS) for Ecological Patterns
    How to use publicly available infection case data to teach ecology and evolution of human infectious diseases.

    Keywords: Evolutionecologyinfectious diseasehumansjigsawsmall group workEvolutionary medicinedata explorationCDCNNDSS

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    A Modeling Exercise in Sexual Selection using a Student-Created Bird Species
    Evolution-centered lessons at the undergraduate level can often be jargon-heavy, propagate misconceptions if taught ineffectively, and be uninteresting to students who may not see the relevancy of...

    Keywords: Evolutionfitnesssexual selectionNatural Selectionintersexual selectionmate choice

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    Cardiac Output
    This module introduces Fick's principle in the context of understanding the cardiac output. It is intended for an introductory biology audience.

    Keywords: linear regressionproportionslinear equationsOpenStaxAnimal Physiology

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    Using an Interactive Game, Gutsy, to Examine the Impacts of Pathogens and Everyday Events on the Human Gut Microbiome
    The human gut microbiome is often associated with ‘good bacteria’ in marketing campaigns for dietary supplements, probiotic drinks, and fermented foods. Yet, the dynamic and complex...

    Keywords: bacteriaGamepathogenhealthmicrobiomediversity

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    Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab
    In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed...

    Keywords: data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research

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    Online exercise: Managing Prairie Dogs for Ferret Reintroduction: A Case Study
    This data-driven ‘ferret reintroduction’ exercise, adapted from https://www.sesync.org/printpdf/2264, was developed for undergraduate students in an online non-majors biology course as a final...
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    Exercise on "Globally endangered sea turtles of the Palmyra Atoll National Wildlife Refuge: A Focus on Scientific Analysis"
    This data-driven endangered sea turtle exercise adapted from http://qubeshub.org was developed for undergraduate students in an online non-majors biology course as a final small group project.

    Keywords: Resource Type

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    Teaching epidemiology and principles of infectious disease using popular media and the case of Typhoid Mary
    Allied health students often struggle to understand how particular content, such as epidemiology, connects to their future careers. This activity uses the case of Typhoid Mary as a foundation for...

    Keywords: epidemiologycase studyinfectous diseasepopular mediaTyphoid Mary

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    Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination
    Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom,...

    Keywords: nucleotidessequencingDNAgel electrophoresisChain Termination

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    Biogeography of plant-associated fungi: who lives where and why?
    This dataset of fungal communities associated with the leaves an endemic Hawaiian tree provides students opportunities to explore relationships between environmental variables and microbial...

    Keywords: small group activityinquiry-based learningbiogeographymicrobial ecology

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    Is Earth Currently Undergoing a Sixth Mass Extinction?
    The five Phanerozoic mass extinctions were central in shaping biodiversity on Earth today. Due to increasing biodiversity losses, there is debate about whether we are currently undergoing a sixth...

    Keywords: conservationBiodiversityextinctionMass ExtinctionDeep Time

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