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    Agent-Based Modeling Course Materials
    Materials created for an upper level ABM course. Prerequisite: Students have taken either (a) another modeling course, or (b) the introductory computer science sequence.

    Keywords: agent-based modelingindividual-based modelingcourse materials

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    A Rapid Genetic Screen Using Wisconsin Fast Plants®: A Hands-On Approach to Inheritance of de novo Mutations
    Some concepts in genetics, such as genetic screens, are complex for students to visualize in a classroom and can be cumbersome to undertake in the laboratory. Typically, very large populations are...

    Keywords: mutationInheritancegermlinesomaplant lifecycle

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    Keep It Shrimple: An Adaptable Student-Driven Research Project for the Introductory Biology Laboratory
    A challenge in introductory biology laboratory courses is to provide students with authentic, engaging research opportunities that allow them to take ownership of their experiments. We present a...

    Keywords: hypothesis testingexperimental designanimal behaviorbrine shrimp

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    1-019-RocksInTheHead-Modeling Scenario
    We describe an experiment with data on the perception of the individual mass of a collection of rocks in comparison to a 100 g brass mass. Students use the logistic differential equation as a...

    Keywords: logistic growthparameter estimationexperiment

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    2000-deOlivera-Delfino-Costa-Leite-Pinhole Water Flow From Cylindrical Bottles
    The water flowing from the first bottle feeds the second one located below it. The same concepts of mass and energy conservation now lead to a non-trivial differential equation for the lowest...

    Keywords: Torricelli's LawConservation of EnergytConservation of MassBernoulli’s Theorem

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    1-074-BottleWaterFlow-ModelingScenario
    We offer an experiment in which data is collected to ascertain a parameter in the differential equation formulation of Torricelli's Law for water flow.

    Keywords: bwaterTorricelli's Lawbottle

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    6-012-RiverCrossing-ModelingScenario
    Students develop a model of a river crossing in a boat with thrust using Newton's Second Law of Motion from a Free Body Diagram they construct. The model is thence a system of one second order...

    Keywords: dragonNewton's Second Law of Motionriver crossinriver currentvelocity profilethrustFree Body Diagram

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    7-010-MultipleDoses-ModelingScenario
    Two multiple dose drug administration regimens are offered. A drug is to maintain a certain level (above a set minimum and below a set maximum) in the blood stream and one regimen involves bolus...

    Keywords: drug discoverystep functiondoseDiracdrug administrationinverse Laplace Transformintraveneousbolussteady drip

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    Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection
    In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection...

    Keywords: cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies

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    1-015-Torricelli-ModelingScenario
    We help students develop a model (Torricelli's Law) for the height of a falling column of water with a small hole in the container at the bottom of the column of water through which water exits the...

    Keywords: dataSpanishtankcolumn of waterapertureTorricelli's LawConservation of EnergytSolverwater flowExcel Solver

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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.

    Keywords: liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model

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    2005-Saifullah-Mathematical Modeling With Differential Equations
    This article aims to provide the students some basic modeling skills, which will have applications to a wide variety of problems.

    Keywords: species interactionsword equationinteractive software

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    1-014-DrainingContainers
    Given two rectangular circular cylinders of water with the same volume, but different radii, with a small bore hole of same radius on the center of the bottom through which water exits the...

    Keywords: containerstankflowTorricelli's Lawdrainingfixed volume

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    1-064-TorricelliBox-ModelingScenario
    The time it takes a column of water to empty and the time it takes the same volume of column of water with a box (various sizes) submerged in the column of water are compared through modeling with...

    Keywords: groundwater flowcolumn of waterTorricelli's Lawwater displacementsubmerged box

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    5-022-ColdPill-ModelingScenario
    A model for the flow of a cold pill drug through the gastrointestinal compartment to the bloodstream compartment of a human subject is proposed. Students solve the system of differential equation...

    Keywords: ratesmedicinedrug discoverycompartmentcold pillgastrointestinalbloodstream

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    6-030-SaltAndTorricelli-ModelingScenario
    We build on a model for the height of a falling column of water with a small hole in the container at the bottom of the column of water. We use data from one video of a falling column of water.

    Keywords: whole picturetankmixingflowcolumn of watersalt mixinggraduated cylinderapertureTorricelli's Law

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    Exploring USGS streamflow data with dataRetrieval and Swirl
    This Swirl lesson walks through how to retrieve, view, and visually analyze streamflow and water quality data from the National Water Information System (US Geological Survey).

    Keywords: tool:swirl

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    Sickle Cell Disease and Natural Selection in Humans
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Cell Aggregation and Sphere Packing
    This module introduces the calculation of packing density in the context of understanding cell aggregation and arrangement. It is intended for an introductory biology audience.

    Keywords: RatiosGeometryInequalitiesCell StructureCell GrowthCell AggregationSphere Packing

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    Hardy-Weinberg Equilibrium
    This module introduces the Hardy-Weinberg model in the context of understanding the population's genotype and allele frequencies. It is intended for an introductory biology audience.

    Keywords: genotypeallelesGenetics and EvolutionFrequenciesHardy-Weinberg model

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