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    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
    Manipulating gene expression is a commonly used tool to study the effect of a single gene or the hierarchy of gene networks in many different biological disciplines. When working with mice, the...

    Keywords: mathematical modelhomologous recombinationCre/loxgene targeting

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    Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination
    Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom,...

    Keywords: nucleotidessequencingDNAgel electrophoresisChain Termination

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    Discovery Poster Project
    Engaging in undergraduate research can be exciting yet intimidating to first-year students at large research universities. For first-generation college students, whose pre-college exposure to...

    Keywords: researchprimary literaturePostercore concepts

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    The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum
    Participation in research provides personal and professional benefits for undergraduates. However, some students face institutional barriers that prevent their entry into research, particularly...

    Keywords: epigeneticsundergraduate researchmendelian inheritanceSelf-EfficacyCUREsnature of scienceResiliencecurriculum strategiesreprogramming

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    The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups
    Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold.  This Lesson uses small...

    Keywords: neuron physiologyspatial summationsynaptic integrationtemporal summationthreshold

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    Two-Way ANOVA
    In this lesson, students will learn the necessary statistical terms to understand two-way ANOVA, how to visualize their data, how to perform two-way ANOVA and interpret their results, and how to...

    Keywords: undergraduate researchANOVA

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    Luria-Delbruck
    These two workbooks model the evolution of phage resistance in a bacterial population under two alternative hypotheses.

    Keywords: ExcelphageResources @ ESTEEMLuria-Delbruckresistance

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    Chi-Square analysis of two point test cross data
    This flash tutorial simulates analysis of a 2 point test cross and will walk you through the analysis of two hypothetical traits.

    Keywords: geneticssimulationchi-squaredlinkagetest crossrecombinationdemonstrationin-class activityproblem set

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    Chapter 10: Two-way analysis of variance
    Biostatistics Using R: A Laboratory Manual was created with the goals of providing biological content to lab sessions by using authentic research data and introducing R programming language....

    Keywords: biostatisticsR programming language

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    A tale of two globins: hemoglobin and myoglobin and oxygen transport
    Hemoglobin and myoglobin are two related proteins important in oxygen binding and transport to cells. However, unlike myoglobin, hemoglobin exhibits positive cooperativity in oxygen binding. Oxygen...
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    1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
    Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two...

    Keywords: LSDcompartmentpharmacokinetics

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    1977-HI_Freedman-P_Whitman-Mathematical models of population interactions with dispersal
    A system of differential equations is proposed as a model of dispersion between two populations in habitats separated by a barrier.

    Keywords: predatorbarriertwo populationstwo habitats

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    Revealing Hidden Figures in Natural History Collections Working Group 2023 Update!
    Our 2023 BIOME Lightning Presentation sharing updates from the Hidden Figures Working Group including the first two published modules!

    Keywords: social justicenatural history collectionshidden figuresbiome23biome2023

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    Hawk vs. Dove Game
    Hawk vs. Dove Game is a model of conflict for two players in game theory.

    Keywords: mathematical modelcomputational modelagent-based model

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    2012-Yuan_Yuan-A coupled plankton system with instantaneous and delayed predation
    We present two simple plankton population models: one has instantaneous predation, another has delayed predation.

    Keywords: phytoplanktonbifurcationorbitsherbivorous zooplanktoneffect of fishmaturation time delay

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    2012-Arvind_Kumar_Misra-A simple mathematical model for the spread of two political parties
    In this paper, a non-linear mathematical model for the spread of two political parties has been proposed and analyzed by using epidemiological approach.

    Keywords: epidemiccompartmentpolitical parties

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    1994-S_S_Everingham-C_Peter_Rydell-Modeling the Demand for Cocaine
    This is a report prepared for the Office of National Drug Control Policy of the United States Army by the Rand Corporation. The report contains lots of data and builds a two compartment difference...

    Keywords: drugstwo compartmentcocainedemand

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    5-014-TwoSpringMass-ModelingScenario
    We ask students to build a Free Body Diagram for a vertical two mass situation in which the two masses are held fixed at the tip and at the bottom. The mass holds the springs together at the join...

    Keywords: massspring mass dampersprings

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    Comparing Primary and Secondary Forest in a Preserve in Plano Texas: A Forest Ecology Course-based Undergraduate Research Experience (CURE) for Non-Majors and Lower-Level Majors
    An activity that can be conducted as an online or field exercise in which students develop and test their hypotheses about how forest stand characteristics differ between two forest types.

    Keywords: forest ecologyecologycourse-based undergraduate research experienceUsing Excel

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    State Apportionment Lesson Plans and Task
    Three secondary teachers and a mathematics education researcher planned two lessons and revised them through lesson study. The teachers adapted the State Apportionment Task from the Mathematical...

    Keywords: votingproportional reasoning

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