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    Towards better modelling and decision support: Documenting model development, testing, and analysis using TRACE
    We introduce TRACE, a framework for documenting model testing and analysis. TRACE is based on the recently proposed framework of model "evaluation" , and is designed to make models fit for...

    Keywords: standardizationgood modelling practicerisk assessmentdecision supportTRACEResources @ QUBES - Teaching & Reference

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    2006-Graves-Peckham-Pastor-2D differential equations model for mutualism
    We develop from basic principles a two-species differential equations model which exhibits mutualistic population interactions.

    Keywords: population dynamicsLotka-Volterragrowth ratemutualismLichen

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    Wolf Sheep Predation Simulation Exercise
    This resource is an exercise to introduce students to agent-based modeling of biological systems through working with a simple existing model.

    Keywords: simulationecologyIntroductoryNetLogoagent-based modelingagent-based modelLabbioinformaticspredator-preyUndergraduateNIBLSEInstructional SettingAudience LevelActivity LengthLess than 1 hoursimulation cycleC1. Role of bioinformaticsC6. ModelsReviewed at NIBLSEagent based modleing

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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.

    Keywords: compartment modelpharmacokineticsnonlinear estimationone compartment model

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    2018-Hu-Huang-Dynamic Regulation Responding to an External Stimulus
    This study examines the dynamic regulation process responding to an external stimulus. This study introduces the driven damped oscillator model which has an additional parameter to identify...

    Keywords: dynamical systemsregulationsteady statesales modelexternal stimulus

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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    Biogeography of Hantavirus Hosts
    Using QGIS, this module introduces students to zoonotic pathogens, host biogeography, the "One Health" concept, forming hypothesis, and natural history museums within the Hantavirus system.

    Keywords: human-environmental interactionsmammalsbiogeographyhypothesis formulationdigitized natural history collectionshuman healthQGISzoonotic diseasesone healthrodentsPathogens

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    2010-Kijek-Kijek-Modelling of Innovation Diffusion
    This paper offers a first order differential equation model for innovation diffusion, solves it, and offers qualitative analysis as well as approaches to estimating parameters with some data on...

    Keywords: Bass modelinnovation diffusionLogistic modeldynamic model

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    2014-Enderling-Chaplain-Mathematical Modeling of Tumor Growth and Treatment
    Herein we describe fundamentals of mathematical modeling of tumor growth and tumor-host interactions, and summarize some of the seminal and most prominent approaches.

    Keywords: cancertumor modelingangiogenesistumor growthpatient care

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    Pharmacokinetics
    This Excel module explores how drugs are processed and absorbed in the human body.

    Keywords: drug metabolismpharmacokinetics

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    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving...

    Keywords: stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates

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    2010-Del-Ciello-EtAl-Modeling Disease
    We model the transmission of a disease through a population. Such modeling is very important to the study of epidemiology and the practice of medicine.

    Keywords: diseasespreadcarriessymptomaticasymptomatic

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    2003-Yildirim-Mackey-Feedback Regulation in the Lactose Operon
    A mathematical model for the regulation of induction in the lac operon in Escherichia coli is presented.

    Keywords: mRNAlactoselactose operonfeedback regulation

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    2001-Edwards-Buckmire-A differential equation model of North American cinematic box-office dynamics
    A new mathematical model is presented for the box-office dynamics of a motion picture released in North America.

    Keywords: cinemamoviesbox-office

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    2013-Deboeck-Bergeman-The reservoir model-DE model of psychological regulation
    The following article describes a differential equation model based on the concept of a reservoir for psychological regulation.

    Keywords: adaptive copingReservoirsNotre Dame Longitudinal Study on Agingoutputinput distributionstressorscoping resources

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    2011-GA_Koch-Noble-Drugs in the Classroom Using Pharmacokinetics to Introduce Biomathematical Modeling
    By beginning with simple model involving the half-life of a drug, students take advantage of their mathematical abilities to explore the biology.

    Keywords: Biomathematicspharmacokinetics

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    2008-Huet-Deffuant-Differential Equation Models Derived from an Individual-Based Model Can Help to Understand Emergent Effects
    We study a model of primacy effect on individual's attitude. Typically, when receiving a strong negative feature first, the individual keeps a negative attitude whatever the number of moderate...

    Keywords: agent-based modelprimacy effectinformation filteringaggregated modelcollectiveinteractionsdouble-modelling

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    A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans
    Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed...

    Keywords: microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a...

    Keywords: bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

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    Data management and introduction to QGIS and RStudio for spatial analysis
    Students learn about the importance of good data management and begin to explore QGIS and RStudio for spatial analysis purposes. Students will explore National Land Cover Database raster data and...

    Keywords: tool:rstudioGISdata managementlandscape ecologyGeospatial ScienceNational Ecological Observatory Networkquantitative inquiryQGIS

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