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    Biogeography of Hantavirus Hosts
    Using QGIS, this module introduces students to zoonotic pathogens, host biogeography, the "One Health" concept, forming hypothesis, and natural history museums within the Hantavirus system.

    Keywords: human-environmental interactionsmammalsbiogeographyhypothesis formulationdigitized natural history collectionshuman healthQGISzoonotic diseasesone healthrodentsPathogens

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    2014-Enderling-Chaplain-Mathematical Modeling of Tumor Growth and Treatment
    Herein we describe fundamentals of mathematical modeling of tumor growth and tumor-host interactions, and summarize some of the seminal and most prominent approaches.

    Keywords: cancertumor modelingangiogenesistumor growthpatient care

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    2008-Yang-EtAl-Differential Equation Model of HIV Infection of CD T-Cells with Delay 
    Abstract: An epidemic model of HIV infection of CD4+ T-cells with cure rate and delay is studied. We include a baseline ODE version of the model, and a differential-delay model with a discrete time...

    Keywords: virusT cellsHopf bifurcationendemic equilibrium

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    Towards better modelling and decision support: Documenting model development, testing, and analysis using TRACE
    We introduce TRACE, a framework for documenting model testing and analysis. TRACE is based on the recently proposed framework of model "evaluation" , and is designed to make models fit for...

    Keywords: standardizationgood modelling practicerisk assessmentdecision supportTRACEResources @ QUBES - Teaching & Reference

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    2006-Graves-Peckham-Pastor-2D differential equations model for mutualism
    We develop from basic principles a two-species differential equations model which exhibits mutualistic population interactions.

    Keywords: population dynamicsLotka-Volterragrowth ratemutualismLichen

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    Data management and introduction to QGIS and RStudio for spatial analysis
    Students learn about the importance of good data management and begin to explore QGIS and RStudio for spatial analysis purposes. Students will explore National Land Cover Database raster data and...

    Keywords: tool:rstudioGISdata managementlandscape ecologyGeospatial ScienceNational Ecological Observatory Networkquantitative inquiryQGIS

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    Wolf Sheep Predation Simulation Exercise
    This resource is an exercise to introduce students to agent-based modeling of biological systems through working with a simple existing model.

    Keywords: simulationecologyIntroductoryNetLogoagent-based modelingagent-based modelLabbioinformaticspredator-preyUndergraduateNIBLSEInstructional SettingAudience LevelActivity LengthLess than 1 hoursimulation cycleC1. Role of bioinformaticsC6. ModelsReviewed at NIBLSEagent based modleing

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    6-024-DronePackageDelivery-ModelingScenario
    Students will derive a system of first order differential equations which describe the flight path of a drone delivering a package.

    Keywords: VectorsTrigonometryFlightdronesparametric curveImproved Euler MethodRunge-Kutta

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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.

    Keywords: compartment modelpharmacokineticsnonlinear estimationone compartment model

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    A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans
    Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed...

    Keywords: microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a...

    Keywords: bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme

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    2018-Hu-Huang-Dynamic Regulation Responding to an External Stimulus
    This study examines the dynamic regulation process responding to an external stimulus. This study introduces the driven damped oscillator model which has an additional parameter to identify...

    Keywords: dynamical systemsregulationsteady statesales modelexternal stimulus

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    Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses
    Our understanding of microbiomes, or the collection of microorganisms and their genes in a given environment, has been revolutionized by technological and computational advances. However, many...

    Keywords: microbiomeDNA SubwayCyVerseCourse based undergraduate researchQIIME2ranacapa

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    2010-Kijek-Kijek-Modelling of Innovation Diffusion
    This paper offers a first order differential equation model for innovation diffusion, solves it, and offers qualitative analysis as well as approaches to estimating parameters with some data on...

    Keywords: Bass modelinnovation diffusionLogistic modeldynamic model

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    Pharmacokinetics
    This Excel module explores how drugs are processed and absorbed in the human body.

    Keywords: drug metabolismpharmacokinetics

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    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving...

    Keywords: stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates

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    2010-Del-Ciello-EtAl-Modeling Disease
    We model the transmission of a disease through a population. Such modeling is very important to the study of epidemiology and the practice of medicine.

    Keywords: diseasespreadcarriessymptomaticasymptomatic

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    2003-Yildirim-Mackey-Feedback Regulation in the Lactose Operon
    A mathematical model for the regulation of induction in the lac operon in Escherichia coli is presented.

    Keywords: mRNAlactoselactose operonfeedback regulation

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    2001-Edwards-Buckmire-A differential equation model of North American cinematic box-office dynamics
    A new mathematical model is presented for the box-office dynamics of a motion picture released in North America.

    Keywords: cinemamoviesbox-office

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