You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    2006-Loyd-Wodarz-Drug Resistance in Acute Viral Infections-Rhinovirus as a Case Study
    We develop an epidemiological model that can be used to address the spread of resistance at the population level, and a virus dynamics model that can be used to study the dynamics of virus over the...

    Keywords: stabilityresistancevirusdrugepidemic competitionimmune responserhinovirus

    141

    views

    49

    downloads

    0

    comments

    0

    adaptations

    2020-TeachingModule-SpreadOfCommonColdSimulation
    This simulation is meant to introduce the idea of a differential equation model and investigate the impact of heightened hygiene and decreased interactions on the spread of an infectious disease....

    Keywords: simulationmoduleinfectious diseasediseasespreadTeaching Modulespread of disease

    293

    views

    895

    downloads

    0

    comments

    0

    adaptations

    Investigating the Ecology of West Nile Virus in the United States
    TIEE Module- How do biotic and abiotic environmental factors explain the historic, present, and future prevalence and range of West Nile Virus (WNV) in the US?
    1062

    views

    210

    downloads

    0

    comments

    1

    adaptations

    Graphing an Epidemic: West Africa Ebola Epidemic
    In this activity, students will explore how the Ebola virus outbreak occurred in West Africa through graphing prevalence, incidence and mortality data from the three major countries that were...

    Keywords: epidemiologyepidemicsEbola

    1224

    views

    834

    downloads

    0

    comments

    0

    adaptations

    1-046-GoingViral-ModelingScenario
    Students participate in a simulation of the spread of a viral disease in the classroom and model the process with a logistic differential equation. The simulation uses random numbers and the entire...

    Keywords: simulationmathematical modeldatalogisticrandom number generatorfittingrandom process

    452

    views

    176

    downloads

    0

    comments

    0

    adaptations

    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

    1639

    views

    237

    downloads

    0

    comments

    0

    adaptations

    1-084-GoingViral-ModelingScenario
    Students employ randomization in order to create a simulation of the spread of a viral disease in a population (the classroom). Students then use qualitative analysis of the expected behavior of...

    Keywords: simulationlogisticrandomfittingpartial fractions

    259

    views

    118

    downloads

    0

    comments

    0

    adaptations

    6-017-OncolyticViruses-ModelingScenario
    Students explore oncolytic virotherapy using systems of differential equations and numerical simulations.

    Keywords: cancercancer-immune dynamicsimmune suppressor drugoncolytic virusvirotherapy

    430

    views

    96

    downloads

    0

    comments

    0

    adaptations

    Targeting Infected Cells for Immune Defense
    This animation shows how a cell infected by a virus signals cytotoxic T cells to destroy itself.

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

    1065

    views

    200

    downloads

    0

    comments

    1

    adaptations

    Sequence Similarity Resource Adaptation: Exploring Ebola Virus
    This adaptation of the sequence similarity resource provides biology students with a basic set of bioinformatics concepts and tools. These concepts and tools are used to explore relationships...

    Keywords: phylogeneticsbioinformaticsEbolasequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogram

    2189

    views

    5541

    downloads

    0

    comments

    0

    adaptations

    Sin Nombre Hantavirus in the US
    A module guiding students through the review of different biodiversity data sources to identify patterns in the distribution of the Sin Nombre Hantavirus in the United States. English, Spanish, and...

    Keywords: Resources @ AIM-UP!infectious diseasespublic healthnatural history collectionsWildlife Diseasedigitized natural history collectionsenglishSpanishzoonotic diseaseshantavirusMEPAPortuguesetranslated

    722

    views

    442

    downloads

    0

    comments

    0

    adaptations

    2018-Van_Kinh Nguyen-Esteban_Hernandez-Vargas-Parameter estimation in mathematical models of viral infections using R
    Mathematical modeling has played a central role to understand mechanisms in different viral infectious diseases. In this approach, biological-based hypotheses are expressed via mathematical...

    Keywords: simulationdiseasevirusviral infection

    249

    views

    65

    downloads

    0

    comments

    0

    adaptations

    Introductory Video and worksheets on Module 1 and 2 on "Sequence Similarity: An inquiry based and under the hood..."
    The video walks the students to complete Module 1 and 2 on Sequence Similarly and Alignment adapted from Tapprich (2019) and Hudson Alpha that teaches these modules within the context of the...

    Keywords: bioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixCourseSource

    1252

    views

    1390

    downloads

    0

    comments

    0

    adaptations

    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

    1108

    views

    4070

    downloads

    0

    comments

    0

    adaptations

    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

    1797

    views

    2321

    downloads

    0

    comments

    2

    adaptations

    COVID-19: Molecular Basis of Infection
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

    2064

    views

    671

    downloads

    0

    comments

    2

    adaptations

    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

    1297

    views

    1755

    downloads

    0

    comments

    0

    adaptations

    2020-Chen_Et_Al-MathModel_Simulation_Phase-Based_Transmissability_Corona_Virus
    In this study, we developed a Bats-Hosts-Reservoir-People transmission network model for simulating the potential transmission from the infection source (probably be bats) to the human infection.

    Keywords: basic reproduction numbercoronavirusnext generation matrixtransmissibilitynovel coronavirus

    122

    views

    43

    downloads

    0

    comments

    0

    adaptations

    1-038-Ebola-ModelingScenario
    Students will use data published by the World Health Organization to model the 2014 outbreak of the Ebola virus in West Africa. We begin with a simple exponential growth model and move through the...

    Keywords: population dynamicsdata analysisexponential growthEbolalogisticepidemic

    1171

    views

    4036

    downloads

    0

    comments

    0

    adaptations

    2008-Yang-EtAl-Differential Equation Model of HIV Infection of CD T-Cells with Delay 
    Abstract: An epidemic model of HIV infection of CD4+ T-cells with cure rate and delay is studied. We include a baseline ODE version of the model, and a differential-delay model with a discrete time...

    Keywords: virusT cellsHopf bifurcationendemic equilibrium

    130

    views

    39

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search