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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Inexpensive Cell Migration Inquiry Lab using Zebrafish
    Cell migration is an important and interesting topic that has the potential to engage students in cell biology by its intrinsically active nature. However, most ways to investigate cell migration...

    Keywords: CytoskeletonCell migrationmodel organisms

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    Taking the Hassle out of Hasselbalch
    Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the...

    Keywords: pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa

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    Undergraduates Learn Evolution Through Teaching Kindergartners About Blind Mexican Cavefish
    The development and implementation of a scientific outreach activity comes with a number of challenges. A successful outreach event must match the sophistication of content to the audience, be...

    Keywords: Evolutionecologymorphologysensory biologycave biologycomparative biologyenvironmental differencesregressive lossstructure and function

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    Dilution and Pipetting Lesson Using Food Dyes
    In this lesson students learn how to use micropipettors to accurately measure small volumes of liquids and perform dilutions using food dyes. Students dilute four food dyes at 10X concentration to...

    Keywords: dilutionCalculationLab SkillsMicropipetting

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    Lights, Camera, Acting Transport! Using role-play to teach membrane transport
    Lights, Camera, Acting Transport! is an active and unique role-play exercise designed to teach introductory biology students basic concepts of passive and active membrane transport. The activity...

    Keywords: ATPcarrierschannelsco-transportelectrogenic pumpfacilitated diffusionmembrane transportpassive transportprimary active transportsimple diffusion

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    You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”
    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented...

    Keywords: bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

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    The Science Behind Parthenogenesis: Interesting things happen when meiosis goes “wrong”
    Parthenogenetic reproduction is a fascinating, complex topic.  This article accompanies “Why Meiosis Matters: The case of the fatherless snake.” It summarizes the basic information...

    Keywords: meiosismitosissex determinationAsexual reproductionParthenogenesis

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    The Case of the Missing Strawberries: RFLP analysis
    While solving the fictional mystery of the missing strawberries, students are engaged in a guided-inquiry lesson featuring small-group and class discussions, hands-on activities, and laboratory...

    Keywords: process of scienceDNAforensicsgel electrophoresisMolecular genotypingRestriction endonucleaseRestriction enzymeRestriction fragment length polymorphismRFLP

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    Helping Students to Overcome STUMPS: Scientific terms undermined by meanings peripheral to science
    Many terms and phrases that are ubiquitous in everyday use have very different meanings in science. As a result, biology students often hold prior conceptions that are difficult to change. In this...

    Keywords: Evolutionfitnessprocess of sciencetree of lifemetacognitionlanguagemisconceptionsTerminologyTheory

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    Wind and Ocean Ecosystems (Project EDDIE)- adapted to provide greater autonomy for students in an upper level class
    This module adaption focuses on the interplay between winds, ocean upwelling, and marine productivity. Students are able to select and download their own data and compare results among different...
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    Exploring USGS streamflow data with dataRetrieval and Swirl
    This Swirl lesson walks through how to retrieve, view, and visually analyze streamflow and water quality data from the National Water Information System (US Geological Survey).

    Keywords: tool:swirl

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    Oyster Restoration Success and Water Quality in the James and Rappahannock Rivers of Virginia
    This QUBES lesson uses statistical analysis to test whether or not oyster restoration sites in Virginia are successfully increasing the number of oysters and whether or not water quality is...

    Keywords: aquatic ecologymarine ecologyggplot2Pearson correlation coefficientSimple Linear RegressionnitrogenJames Rivertidyversechesapeake baywater qualityphosphorusharmful algae bloomsvirginia

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    Wind and Ocean Ecosystems (Project EDDIE)
    This module introduces students to the concepts of Ekman transport, eastern boundary currents, and upwelling, while learning how to find a location on a map using latitude and longitude, how to...
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    Food, Energy and Water Learning Modules (FEWLM) Workbooks
    FEWLM is a low-cost inquiry-based interdisciplinary STEM prototypical curriculum built on Next Generation Science Standards, systems thinking and informed engineering design pedagogy.

    Keywords: K-12inquiry-based learningNext Generation Science StandardsSystem Thinking

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    Examining the Physiology Behind the Symptoms of Lactose Intolerance
    This is a set of extension questions for the HHMI short film The Making of the Fittest: Got Lactase? The Co-evolution of Genes Video Activity.
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    Mosquito Surveys Along Anthropogenic Impact Gradients: EREN-NEON Flexible Learning Project
    This project explores the role of human land use and other environmental factors that affect native and invasive mosquito species distributions and the diseases that they can vector.
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    Investigating human impacts on stream ecology: locally and nationally
    TIEE Module- How does nutrient pollution impact stream ecosystems locally and nationally? This is an adaptation of the module that includes statistical testing and links sections to a lab report...
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    Investigating human impacts on stream ecology: locally and nationally
    This is a modification of an original TIEE Module, investigating these questions: How does nutrient pollution impact stream ecosystems locally and nationally? How does land cover change impact...

    Keywords: tool:rstudiolandscape ecologyStream ecologyBox Plotsland usespatial analysisEutrophication

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    A Tough Choice in Watershed Management
    In this Team-based activity, students work in teams, playing the role of natural resource managers who must decide in which region to invest limited funding for nutrient reduction in streams....

    Keywords: Stream ecologyBox PlotsSpreadsheetGroup cooperative learningTeam-based LearningBiogeochemical cycles

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    Diving into Deep Sea Data
    A module that combines NOAA's Okeanos Explorer and the iDigBio Portal to explore the deep sea!

    Keywords: Querying databasesremote sensingnatural history collectionsfishesscientific name5ESpeciesichthyologydeep sea

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