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Ethics in Synthetic Biology

By Lisa Scheifele

Loyola University Maryland

This collection of four activities provide students with an introduction to thinking about ethical concerns in human genome synthesis, gene editing, metabolic engineering, and synthetic genomes.

Listed in Teaching Materials | resource by group Build A Genome Network

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Version 1.0 - published on 15 Aug 2019 doi:10.25334/TCG2-GP43 - cite this

Licensed under CC Attribution-ShareAlike 4.0 International according to these terms

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Description

Build a Genome Network (BAG) is a course-based undergraduate research experience in which students create synthetic genomes. Pioneered at Johns Hopkins University in 2007, BAG was integral to the international effort to create the first synthetic eukaryotic genome (the Synthetic Yeast Project) and helped initiate the teaching of synthetic biology to undergraduates. This interdisciplinary course-based research experience allows students to learn concepts and techniques in genomics, bioinformatics, molecular biology, and synthetic biology while participating in a cutting-edge research project.

For additional information please visit the BAG group on QUBES

Contents

  • Group: Build A Genome Network
  • Ethics in synthetic genomics (v1.0)

    This is an ethical reflection for students on an issue in genome engineering and the synthesis of potentially infectious viruses. The case study asks students to reflect on material in the linked article. Also included is the grading rubric.

  • Ethics of Gene Editing (v1.0)

    This is an ethical reflection for students on an issue in gene editing. The case study asks students to reflect on material in the two linked articles. Also included is the grading rubric.

  • Ethics of Metabolic engineering (v1.0)

    This is an ethical reflection for students on an issue in metabolic engineering and the potential for "home-brew" morphine. The case study asks students to reflect on material in the linked article. Also included is the grading rubric.

  • Should we synthesize a human genome? (v1.0)

    Two articles introducing the Human Genome Project-Write and asking questions about the ethics of the project.

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