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Cell Division and Cancer Risk Data Point

By HHMI BioInteractive

Cancer is typically attributed to hereditary and environmental factors, but these only explain a fraction of overall cancer risk. This activity explores a third factor.

Listed in Teaching Materials | resource by group HHMI BioInteractive

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Version 1.0 - published on 17 Jan 2018 doi:10.25334/Q4VH55 - cite this

Licensed under CC Attribution-NonCommercial-NoDerivatives 4.0 International according to these terms

cancer activity cell.PNG

Description

Relationship between the risk of cancer and the number of times stem cells divide in different types of body tissue over the course of a person’s lifetime. Lifetime risk (y-axis) is expressed as the base 10 logarithm of the probability of developing cancer, where 10-1is 10% risk, 10-2 is 1% risk, and so forth.

Download the educator guide PDF, which includes questions to guide a class discussion on the graph characteristics and what the data show.

Figure 1 from:

Cristian Tomasetti and Bert Vogelstein. Variation in cancer risk among tissues can be explained by the number of stem cell divisions. Science 347 (6217), 78-81.

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