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Complete Set of Lessons

By Anne Rosenwald1, Gaurav Arora2, Vinayak Mathur3

1. Georgetown University 2. Gallaudet University 3. Cabrini University

The Genome Solver Project began as a way to teach faculty some basic skills in bioinformatics - no coding or scripting. These Lessons also work well in the undergraduate classroom, culminating with an authentic community research project.

Listed in Teaching Materials | resource by group Genome Solver

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Version 1.0 - published on 01 Nov 2018 doi:10.25334/Q4WM78 - cite this

Licensed under CC Attribution-ShareAlike 4.0 International according to these terms

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Description

There are 6 Lessons in the Genome Solver Project

  • Lesson I - Introduction
  • Lesson II - Databases
  • Lesson III - Annotation 
  • Lesson IV - Comparative Genomics 
  • Lesson V - Phylogenetics 
  • Lesson VI - The Community Science Project on Horizontal Gene Transfer 

Each lesson contains a slide deck and transcript.  Lessons II - V also have exercises to practice the tools introduced in that slide deck.  Each of the first five lessons takes an hour or less of class time, lecture and exercise.  By working through the first 5 lessons, participants will have the skills necessary to participate in the Community Science Project, an effort to understand the extent to which exchanges of genetic material from bacteriophages and bacteria drives bacterial diversity and evolution.  

Contents

  • Lesson I - Introduction to Genome Solver (v1.0)

    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Part I is the Introduction to the Genome Solver Project.

  • Lesson II - Databases (v1.0)

    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson II introduces the principal databases for microbial genomics.

  • Lesson III - Annotation (v1.0)

    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson III introduces Annotation, or assigning meaning to all the A's, C's, T's, and G's.

  • Lesson IV - Comparative Genomics (v1.0)

    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson IV, Comparative Genomics, discusses some of the tools available for looking at genes across different genomes.

  • Lesson V - Phylogenetics (v1.0)

    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson V is an introduction to Phylogenetics.

  • Lesson VI - The Community Science Project (v1.0)

    Genome Solver's Community Science Project was developed as a way to use the skills taught in the previous lessons. We're asking members of the community to provide instances of potential phage genes embedded in bacterial genomes.

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Notes

Materials were updated as of Fall 2018.  Note that because the slide decks and exercises point to external websites and web-based tools, some of the illustrations contained in the materials may not look exactly like the live website.  Functionality is usually unchanged. 

Genome Solver

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