We have designed a plug-and-play CURE model that allows students to learn the process of science, specific skills (e.g., sampling, sample processing, metabolomics plates, PCR, sequencing, ecological health analysis methods, etc.), and science communication. The CURE is adaptable and modularized, allowing learners and educators to mix-and-match methods and resources for active learning. Our CUREs are all centered on microbial diversity and ecology, and were originally based on the TinyEarth and S…