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A clicker-based case study that untangles student thinking about the processes in the central dogma
27 Aug 2021 | Teaching Materials | Contributor(s):
By Karen Nicole Pelletreau1, Tessa Andrews2, Norris Armstrong2, Mary A Bedell2, Farahad Dastoor1, Neta Dean3, Susan Erster3, Cori Fata-Hartley4, Nancy Guild5, Hamish Greig1, David Hall2, Jennifer K Knight5, Donna Koslowsky4, Paula Lemons2, Jennifer Martin5, Jill McCourt2, John Merrill4, Rosa Moscarella4, Ross Nehm3, Robert Northington1, Brian Olsen1, Luanna Prevost6, Jon Stolzfus4, Mark Urban-Lurain4, Michelle K. Smith1
1. University of Maine 2. University of Georgia 3. Stony Brook University 4. Michigan State University 5. University of Colorado Boulder 6. University of South Florida
The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students...
Predicting and classifying effects of insertion and deletion mutations on protein coding regions
26 Aug 2021 | Teaching Materials | Contributor(s):
By Joseph Ross
California State University, Fresno
Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...
Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
By Tara Phelps-Durr
Students require a deep understanding of the central dogma before they can understand complex topics such as evolution and biochemical disorders. However, getting undergraduate biology students to...
Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
25 Aug 2021 | Teaching Materials | Contributor(s):
By Todd T. Eckdahl1, A. Malcolm Campbell2
1. Missouri Western State University 2. Davidson College
Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students...
Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)
24 Aug 2021 | Teaching Materials | Contributor(s):
By A. Malcolm Campbell1, Todd T. Eckdahl2
1. Davidson College 2. Missouri Western State University
Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to...
Building creatures with the central dogma of biology
02 Dec 2019 | Teaching Materials | Contributor(s):
By Melissa Skyer
National Technical Institute for the Deaf at Rochester Institute of Technology
Activity that demonstrates how nucleotide changes can affect phenotypes
04 Jan 2019 | Teaching Materials | Contributor(s):
This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.