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Student-Generated Analogies for Learning about Information Flow
19 Apr 2024 | Teaching Materials | Contributor(s):
By Dina L. Newman*1, Crystal Uminski1, L. Kate Wright1
Rochester Institute of Technology
Using analogies is a standard practice for both teaching and communicating ideas in science. Here we upend the traditional lesson, where the instructor provides a fully constructed analogy and...
https://qubeshub.org/publications/4706/?v=1
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Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes
21 Jun 2023 | Teaching Materials | Contributor(s):
By Jyothi Kumar*1, Fabio Gomez-Cano†1, Seth W. Hunt†1, Serena G. Lotreck†1, Davis T. Mathieu†1, McKena L. Wilson†1, Tammy M. Long*1
Michigan State University
Technologies like next-generation sequencing, proteomics, and high-throughput phenotyping have transformed the way we do biology. There is a continued need for scientists with computational skills...
https://qubeshub.org/publications/4356/?v=1
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Garden Variety Mutations: Using Primary Data to Understand the Central Dogma in Large-Lecture Introductory Biology
22 Nov 2022 | Teaching Materials | Contributor(s):
By Jacob Woodbury†1, Jessie B. Arneson†2, Jacey Anderson1, Larry Collins3, Andy Cavagnetto1, William Davis1, Erika G. Offerdahl*1
1. Washington State University 2. University of Jamestown 3. Delta State University
The ability to interpret and create an argument from data is a crucial skill for budding scientists, yet one that is seldom practiced in introductory courses. During this argumentation module,...
https://qubeshub.org/publications/3559/?v=1
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A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation
31 Oct 2022 | Teaching Materials | Contributor(s):
By Lauren J. Hodkinson†1, Julia L. Gross†2, Leila E. Rieder*1
1. Emory University 2. Emory University, National Institute of Allergy and Infectious Disease
Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is...
https://qubeshub.org/publications/3558/?v=1
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Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
28 Apr 2022 | Teaching Materials | Contributor(s):
By Jessie B. Arneson1, Jacob Woodbury1, Jacey Anderson1, Larry B. Collins2, Andy Cavagnetto1, William B. Davis1, Erika G. Offerdahl*1
1. Washington State University 2. Washington State University, Delta State University
At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...
https://qubeshub.org/publications/2863/?v=1
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Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
27 Jan 2022 | Teaching Materials | Contributor(s):
By Abby E. Hare-Harris
Bloomsburg University
The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...
https://qubeshub.org/publications/2817/?v=1
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A clicker-based case study that untangles student thinking about the processes in the central dogma
27 Aug 2021 | Teaching Materials | Contributor(s):
By Karen Nicole Pelletreau1, Tessa Andrews2, Norris Armstrong2, Mary A Bedell2, Farahad Dastoor1, Neta Dean3, Susan Erster3, Cori Fata-Hartley4, Nancy Guild5, Hamish Greig1, David Hall2, Jennifer K Knight5, Donna Koslowsky4, Paula Lemons2, Jennifer Martin5, Jill McCourt2, John Merrill4, Rosa Moscarella4, Ross Nehm3, Robert Northington1, Brian Olsen1, Luanna Prevost6, Jon Stolzfus4, Mark Urban-Lurain4, Michelle K. Smith1
1. University of Maine 2. University of Georgia 3. Stony Brook University 4. Michigan State University 5. University of Colorado Boulder 6. University of South Florida
The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students...
https://qubeshub.org/publications/2577/?v=1
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Predicting and classifying effects of insertion and deletion mutations on protein coding regions
26 Aug 2021 | Teaching Materials | Contributor(s):
By Joseph Ross
California State University, Fresno
Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...
https://qubeshub.org/publications/2569/?v=1
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Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
26 Aug 2021 | Teaching Materials | Contributor(s):
By Tara Phelps-Durr
Radford University
Students require a deep understanding of the central dogma before they can understand complex topics such as evolution and biochemical disorders. However, getting undergraduate biology students to...
https://qubeshub.org/publications/2563/?v=1
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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Genetics (analyzing mutant promoters)
25 Aug 2021 | Teaching Materials | Contributor(s):
By Todd T. Eckdahl1, A. Malcolm Campbell2
1. Missouri Western State University 2. Davidson College
Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students...
https://qubeshub.org/publications/2551/?v=1
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Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)
24 Aug 2021 | Teaching Materials | Contributor(s):
By A. Malcolm Campbell1, Todd T. Eckdahl2
1. Davidson College 2. Missouri Western State University
Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to...
https://qubeshub.org/publications/2547/?v=1
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Building creatures with the central dogma of biology
02 Dec 2019 | Teaching Materials | Contributor(s):
By Melissa Skyer
National Technical Institute for the Deaf at Rochester Institute of Technology
Activity that demonstrates how nucleotide changes can affect phenotypes
https://qubeshub.org/publications/1445/?v=1
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Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
04 Jan 2019 | Teaching Materials | Contributor(s):
By Tara Phelps-Durr
Radford University
This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.
https://qubeshub.org/publications/1006/?v=1