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Marina E Tourlakis
https://qubeshub.org/community/members/32610
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Mol* Adaptation: Case of Severe Insulin Resistance
23 Jul 2021 | Teaching Materials | Contributor(s):
By Keith A. Johnson
Bradley University College of Liberal Arts and Sciences
This is an adaptation using Mol* on the original case written. This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to...
https://qubeshub.org/publications/2483/?v=1
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Happy Blue Baby
09 Jun 2021 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu
Boston University, Chemistry Department
This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...
https://qubeshub.org/publications/2419/?v=1
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COVID-19: Molecular Basis Infection Revisited One Year into the Pandemic
09 Jun 2021 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu
Boston University, Chemistry Department
This adaptation was written in Spring 2021 exactly one year after the original case and includes explorations of the emerging mutations within the spike protein
https://qubeshub.org/publications/2424/?v=1
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Waking up Anna - Adaptations and Conversion to Mol*
08 Jun 2021 | Teaching Materials | Contributor(s):
By Keith A. Johnson
Bradley University College of Liberal Arts and Sciences
This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.The adaptations addressed question clarity and reformatting to use Mol*.
https://qubeshub.org/publications/2420/?v=1
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Happy Blue Baby: MCQs for large classes
18 May 2021 | Teaching Materials | Contributor(s):
By "KP" Kristen Procko
The University of Texas at Austin
Multiple choice questions for the Happy Blue Baby case study pre-work
https://qubeshub.org/publications/2381/?v=1
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CRISPR Gene Editing: Designing the gRNA and Donor Template
15 Jul 2020 | Teaching Materials | Contributor(s):
By Laurel Lorenz
Princeton
In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...
https://qubeshub.org/publications/1962/?v=1
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Understanding COVID-19 Biology to Design a Vaccine - Ethics supplement
08 Jul 2020 | Teaching Materials | Contributor(s):
By Keith A. Johnson
Bradley University College of Liberal Arts and Sciences
The adaptation to Understanding COVID-19 Biology to Design a Vaccine entails two ethics supplements. The first supplement addresses the use of off-label drugs in the pandemic (or other situation)....
https://qubeshub.org/publications/1955/?v=1
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COVID-19: Molecular Basis of Infection-ADAPTATION
17 Jun 2020 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu
Boston University, Chemistry Department
This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...
https://qubeshub.org/publications/1936/?v=1
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Molecular Basis of Sickle Cell Disease
15 Jun 2020 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu
Boston University, Chemistry Department
This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...
https://qubeshub.org/publications/1925/?v=1
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The Happy Blue Baby Hemoglobin
14 Jun 2020 | Teaching Materials | Contributor(s):
By Kasandra Jean-Louise Riley1, Shuchismita Dutta2
1. Rollins College 2. RCSB Protein Data Bank, Rutgers University
This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.
https://qubeshub.org/publications/1924/?v=1
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Nicholas' Story
13 Jun 2020 | Teaching Materials | Contributor(s):
By Nik Tsotakos
Penn State Harrisburg
This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.
https://qubeshub.org/publications/1919/?v=1
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COVID-19: On the way to a vaccine
13 Jun 2020 | Teaching Materials | Contributor(s):
By Nik Tsotakos
Penn State Harrisburg
This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.
https://qubeshub.org/publications/1918/?v=1
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Understanding COVID-19 Biology to Design a Vaccine
12 Jun 2020 | Teaching Materials | Contributor(s):
By Keith Johnson1, Didem Vardar-Ulu2, Shuchismita Dutta3
1. Bradley University College of Liberal Arts and Sciences 2. Boston University 3. RCSB Protein Data Bank, Rutgers University
This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...
https://qubeshub.org/publications/1904/?v=1
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COVID-19: Molecular Basis of Infection
12 Jun 2020 | Teaching Materials | Contributor(s):
By Didem Vardar-Ulu1, Shuchismita Dutta2
1. Boston University 2. RCSB Protein Data Bank, Rutgers University
This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...
https://qubeshub.org/publications/1912/?v=1
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A Case of Severe Insulin Resistance
12 Jun 2020 | Teaching Materials | Contributor(s):
By Melanie Lenahan1, Shuchismita Dutta2
1. Raritan Valley Community College 2. RCSB Protein Data Bank, Rutgers University
This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.
https://qubeshub.org/publications/1911/?v=1
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Evolution of Caffeine Biosynthesis Enzymes
12 Jun 2020 | Teaching Materials | Contributor(s):
By Brian Sullivan1, Shuchismita Dutta2
1. University of North Carolina 2. RCSB Protein Data Bank, Rutgers University
This case focuses on exploring why plants make secondary metabolites like caffeine and how the enzymes required for making caffeine evolved.
https://qubeshub.org/publications/1909/?v=1
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Piwi Matters
12 Jun 2020 | Teaching Materials | Contributor(s):
By Laurel Lorenz1, Shuchismita Dutta2
1. Princeton University 2. RCSB Protein Data Bank, Rutgers University
This case focuses on understanding structure and function relationships in Piwi, a protein that is critical for germline stem cell function and development of eggs in the fruit fly ovary.
https://qubeshub.org/publications/1910/?v=1
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Waking up Anna
11 Jun 2020 | Teaching Materials | Contributor(s):
By Kate K. O'Toole1, Shuchismita Dutta2
1. Emory University 2. RCSB Protein Data Bank, Rutgers University
This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.
https://qubeshub.org/publications/1908/?v=1
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Happy Blue Baby
11 Jun 2020 | Teaching Materials | Contributor(s):
By Shuchismita Dutta
RCSB Protein Data Bank, Rutgers University
This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...
https://qubeshub.org/publications/1902/?v=1