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Creating Phylogenetic Trees from DNA Sequences

Author(s): HHMI BioInteractive

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Summary:
This interactive module shows how DNA sequences can be used to infer evolutionary relationships among organisms and represent them as phylogenetic trees.

Licensed under CC Attribution-NonCommercial-NoDerivatives 4.0 International according to these terms

Version 1.0 - published on 22 Jul 2020 doi:10.25334/8W85-BC15 - cite this

Description

Phylogenetic trees are diagrams of evolutionary relationships among organisms. Scientists can estimate these relationships by studying the organisms’ DNA sequences. As the organisms evolve and diverge, their DNA sequences accumulate mutations. Scientists compare these mutations using sequence alignments to reconstruct evolutionary history.

The accompanying “Worksheet” guides students’ exploration of the Click & Learn.

Student Learning Targets

  • Explain how molecular sequences, such as DNA, can be used to study evolutionary relationships.
  • Summarize the process and goals of DNA sequence alignment. 
  • Interpret a simple phylogenetic tree.

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