Using Nanoparticles to Treat Cancer Scientist Spotlight
Author(s): Jennifer Wade1, Hyeyoun Chang2
1. Massachusetts College of Pharmacy and Health Sciences 2. Dana Farber Cancer Institute
1119 total view(s), 415 download(s)
- nanoparticles worksheet.docx(DOCX | 13 KB)
- Scientist Spotlight final.pptx(PPTX | 5 MB)
- Wade Using Nanoparticles Instructor Guide.docx(DOCX | 24 KB)
- License terms
Description
In this activity, students will review the advantages and disadvantages of currently used treatments for cancer. They will then be introduced to a novel therapeutic approach currently under development: the use of nanoparticles that are selectively engulfed by cancer cells to deliver cytotoxic drugs. They will view images of fluorescently stained cells to determine which type of nanoparticle works best to selectively target the cytotoxic agent to cancer cells while sparing healthy cells. They will then read a bar graph showing quantitative image analysis of the images they have viewed. Finally, students will view an interview with the scientist responsible for this experiment, Dr. Hyeyoun Chang. In this interview, Dr. Chang describes her childhood and education, and talks about why she finds research to be a rewarding career.
Learning Outcomes
Quantitative learning outcomes
1. Students will be able to describe how fluorescence intensity can be quantitated and used for statistical determination of differences between samples
2. Students will be able to interpret a bar graph generated using quantitative data about fluorescence intensity
Content learning outcomes
1. Students will be able to describe the challenges associated with treating cancer and the advantages and disadvantages of current cancer treatments
2. Students will be able to describe how nanoparticles could be used to selectively deliver drugs to cancer cells while sparing healthy cells
Social justice and/or diversity/equity/inclusion learning outcomes
1. Students will learn that scientists have diverse backgrounds and interests
2. Students will be better able to see themselves as scientists
Cite this work
Researchers should cite this work as follows:
- Wade, J., Chang, H. (2021). Using Nanoparticles to Treat Cancer Scientist Spotlight. Scientists Spotlights and Data Nuggets, QUBES Educational Resources. doi:10.25334/MY74-KA76