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Needleman - Wunsch Algorithm Exercise

Author(s): Michael Sierk1, Sam S Donovan2, Neal Grandgenett, Bill Morgan3, Mark A. Pauley4, Elizabeth Ryder5

1. Saint Vincent College 2. University of Pittsburgh 3. The College of Wooster 4. University of Nebraska at Omaha 5. Worcester Polytechnic Institute

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Summary:
This exercise is used in a sophomore-junior level bioinformatics course. The algorithm is introduced to the students who then complete the exercise.

Licensed under Creative Commons CC0 1.0 Universal

Version 2.0 - published on 13 Oct 2016 Last public release: 4.0

Keywords

  1. bioinformatics
  2. Undergraduate
  3. NIBLSE
  4. algorithms
  5. incubators
  6. Audience Level
  7. Advanced
  8. Activity Length
  9. 1 Hour
  10. Needleman-Wunsch
  11. C2. Computational concepts

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    Description

    This exercise is used in a sophomore-junior level bioinformatics course. The algorithm is introduced to the students who then spend around 15 minutes filling out the diagram. Students have typically been doing some sequence alignment exercises, such as BLAST searches, and have used different scoring systems to score different short alignments, so they are familiar with sequence alignments and the concept of scoring the alignments, but they have not been exposed to how to generate an alignment. 

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