You are here: Home / Resources / Teaching Materials / Permeability of Molecules / Description
Resource Image

Permeability of Molecules

Author(s): Lou Gross1, Monica Beals1, Susan Harrell1

University of Tennessee Knoxville

1077 total view(s), 221 download(s)

0 comment(s) (Post a comment)

Download

Adapt 0
Summary:
This module introduces Overton's Rule in the context of understanding the permeability of molecules across the cell membrane. It is intended for an introductory biology audience.

Licensed under CC Attribution-ShareAlike 4.0 International according to these terms

Version 1.0 - published on 10 Dec 2018 doi:10.25334/Q4JT77 - cite this

Keywords

  1. linear regression
  2. Permeability
  3. Cell Structure
  4. Cell Membrane
  5. OpenStax
  6. phospholipid membrane
  7. log-log plots
  8. Overton's rule

Alignments

  1. Resource Type
  2. Audience Level
  3. Activity Length
Contents:
view all files

Description

This activity maps to the OpenStax biology textbook, 5.2 Passive Transport

Student Introduction: In the late 1800's, E. Overton discovered that substances that dissolve in lipids pass more easily into the cell than those that dissolve in water. This was some of the first evidence that cells were surrounded by a lipid membrane. The phospholipid membrane of cells can greatly modify the permeation of molecules into a cell. The membrane acts as a barrier to passive diffusion of water-soluble molecules. However, substances that dissolve in lipids pass more easily into the cell. The correlation between permeability and solubility in lipidly is appropriately named Overton's Rule.

Cite this work

Researchers should cite this work as follows:

Close

Home

Search