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    Nature’s Flying Machines: The Evolutionary Relationship of Avian Form & Function
    In this series of activities, birds will be used as the model organism. The modules examine the connections between body form and function over time by investigating the relationship between avian...

    Keywords: evolutionary ecologyCommunity Ecology

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    Louse Genetics, Genomics, and Gene Function...Oh My!
    In this module, students will be investigating a louse gene with an unknown function to determine if it might be important in the evolution of the louse ecomorphs.

    Keywords: parasitesgenomicsgene sequence analysisFunctional Genomics

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    Plants We Eat: Learning Form and Function from Fruits and Vegetables
    This high school or undergraduate lab consists of four activities that guide students through learning about plant parts from the fruits and vegetables with which they are already familiar....
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    Curvature and Maximum Permissible Speeds
    In this activity students will compute the curvature of a section of commuter rail and use it to determine a safe speed at which a train should can round the corner without tipping or derailing....

    Keywords: data analysiscalculusnumerical approximationengineeringcalculus 3transportation

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    Birds and Lice: Reciprocal Natural Selection
    This exercise investigates the form and function of lice and their relationship to their bird host.

    Keywords: BiodiversityparasitesbirdsCoevolutionnatural history collections

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    Cystic Fibrosis Mechanism and Treatment
    This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymacromoleculesGenetic diseaseCell Structure & Function

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    235

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    Quantifying Bacterial Growth in the Guts and Hemolymph of Fruit Flies: Mathematical Modeling and Data Interpolation/Extrapolation
    In this activity, students will analyze raw data obtained from an experiment that explores the effect of overexpressing the Ssk protein in order to strengthen the intestinal barrier and prevent...

    Keywords: graphingexponential growthlinear modelsqbccinterpolationConcepts in Statistics and Precalculus Understanding exponential rates and linear slopesExtrapolation

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    Making “sense” out of surface area to volume relationships
    Using a multimodal approach, the non-linear aspect of the surface area to volume relationship is explored. Students use their their senses of taste and sight to determine how smaller cells and...

    Keywords: active learningintroductory biologycell biologyquantitative skillskinesthetic learningLDC2023

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    Kinetics of a Highly Conserved Enzyme - Carbonic Anhydrase
    This module contains exercises designed to introduce students to graphical representation of biological data. Students will explore the fundamental principles of enzyme kinetics including...

    Keywords: Excelintroductory biologycell biologygraphingslopeQuantitative reasoningdata visualizationquantitative biologyinterdisciplaryquantitative skillscorrelationenzyme functionInterpreting GraphsMichaelis-Mentenenzyme kineticsEnzyme activityenzyme inhibitionLinear and nonlinear analysisNIQBC2. Data and GraphsC4. mathematical modelsenzyme-substrateNIQB Interdisciplinary Quantitative Reasoningcarbonic anhydrase

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    Morphological identification of mosquitoes through microscopic observation
    Scientific research is integrated into various stages of student learning, but hands-on involvement in the research process typically begins at the university level. This module aims to engage high...

    Keywords: modulebiologyproject based learningmosquitoScientific researchMicroscope usedigital accessibility

    391

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    Advanced Student Molecular Case Study Authorship Scaffolded Project and Rubric
    Instructions, assignment prompts, and a rubric for assessing advanced undergraduate authorship of molecular case studies
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    Case Study: Pollination of the Early Spider Orchid (Ophrys sphegodes) by the Solitary Bee (Andrena nigroaenea)
    The research uses natural history collection data to explore a potential phenological shift between an orchid that employs sexual deception and a solitary bee.

    Keywords: pollination biologyClimate change and phenologydigitized natural history collectionsPseudocopulation

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    Introduction to Genome Annotation
    This exercise is an adaptation of the Annotation Lesson by Rosenwald et al. It introduces the use of bioinformatics tools to extract information from genome databases. It is a basic lesson on...

    Keywords: microbiologyGenome annotationBioinformatics EducationBioinformatics and Genomics

    1986

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    709

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    Aquatic Nutrient Levels and Climate Change
    This learning module was designed to introduce students to the aquatic nutrients nitrogen and phosphorus, their roles in ecosystem function and nutrient pollution, and what impacts climate change...

    Keywords: climate changenitrogenwater resourcesfreshwater systemsEutrophicationwater qualitynutrient pollutionphosphorusdischargeTMDL

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

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    Linear Regression (Excel) and Cellular Respiration for Biology, Chemistry and Mathematics
    Students typically find linear regression analysis of data sets in a biology classroom challenging. These activities could be used in a Biology, Chemistry, Mathematics, or Statistics course. The...

    Keywords: statisticsmathematicsdata analysisdatalinear regressionbiologyonlinegraphinglinear equationsQuantitative reasoningassessmentcollege algebracellstatistical analysisregressionOERAlgebrachemistryModelscorrelationSimple Linear RegressionMicrosoft Excellab activityexperimentCellular ProcessesATPqbccUsing Excelmanipulate equationsCellular and Molecular BiologyConcepts in Statisticsoxidationline of best fitexplaining statisticsusing statisticsCellular RespirationPredictionsRespirationgraphing in ExcelLinear CorrelationExothermic Reactioncreate scatter plotAdenosine Triphosphate (ATP)germinating peasPre-lab activityStudent activityHybridCollecting DataR-squareRegression ModelFunctionDependent VariablesIndependent VariablesLinear EquationLinear Equation in two variablescreate graphcreate equationcreate regressioncreate plotinterpret regressioninterpret data

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    Hardy-Weinberg Equilibrium: a swirl resource
    Students will use swirl to understand Hardy-Weinberg equilibrium. The lesson starts with observed numbers of individuals for each genotype, and students will work through a number of steps to...

    Keywords: Hardy-Weinbergpopulation geneticsEvolutionevolutionary ecologyR programming languageSwirl

    1987

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    993

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    The Insect Predation Game: Evolving Prey Defenses and Predator Responses
    Laboratory experiment included in Teaching Issues and Experiments in Ecology (TIEE) Volume 4

    Keywords: simulationpredator-preypredation ecology

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    The Insect Predation Game: Evolving Prey Defenses and Predator Responses
    Laboratory experiment included in Teaching Issues and Experiments in Ecology (TIEE) Volume 4

    Keywords: simulationpredator-preypredation ecology

    2023

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    818

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