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    Drug screening and cancer resistance: EGFR Activity
    This activity explores a specific gene (egfr) and its role in cancer. EGFR was introduced with the Gene Card Activities, researched throughout the semester, and then authentic image data of...

    Keywords: Resources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    Investigating Sexually Transmitted Disease (STD) Ecologies Using Geographic Information Systems (GIS) (Abstract) | TIEE
    Identifying, mapping and understanding the magnitude and the spatial prevalence of the Sexually Transmitted Diseases (STDs) such as chlamydia and gonorrhea diseases. Analyzing the spatial trends of...

    Keywords: Resources @ ESA - TIEEDisease ecologyfmnDIGhuman ecology and behaviorbacterial infectionsspatial and temporal spread of diseaseGeographic Information System (GIS)

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    Ecology of Infectious Disease: Data Mining the National Notifiable Diseases Surveillance System (NNDSS) for Ecological Patterns
    How to use publicly available infection case data to teach ecology and evolution of human infectious diseases.

    Keywords: Evolutionecologyinfectious diseasehumansjigsawsmall group workEvolutionary medicinedata explorationCDCNNDSS

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    Phylogenetic analysis using collections material: interpreting trait evolution by comparison of morphological and molecular genetic hypotheses
    Exercise spans two weeks, includes homework, and involves some groups of animals as well as plants. Emphasizes re-interpretation of morphological trait evolution following molecular genetic...

    Keywords: Evolutionmorphologyphylogenylaboratoryplantsbiological collectionsmolecular analysis

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    Sin Nombre Hantavirus in the US
    A module guiding students through the review of different biodiversity data sources to identify patterns in the distribution of the Sin Nombre Hantavirus in the United States. English, Spanish, and...

    Keywords: Resources @ AIM-UP!infectious diseasespublic healthnatural history collectionsWildlife Diseasedigitized natural history collectionsenglishSpanishzoonotic diseaseshantavirusMEPAPortuguesetranslated

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    SKILLS DEVELOPMENT - Toxicology MSDT
    On this website you can find 6 learning modules on various topics in toxicology. These are self-paced student-centered online learning modules. You will receive a certificate of completion at the...

    Keywords: pathophysiologyregulatory toxicologyprinciples of toxicologybiochemistry and molecular geneticsprinciples of genetic toxicologyapplied systems toxicology

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    The Human Microbiome Biodiversity in Health and Disease
    The students will analyze the human gut and vaginal microbiomes in healthy and diseased states using diversity of bacteria as determined by 16SrRNA sequence.
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    Processes that Regulate Patterns of Species and Genetic Diversity
    TIEE Module- This activity was developed for an undergraduate upper level course for natural resources majors. Classes of 20 – 30 students work best for the activity.
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    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Processes that Regulate Patterns of Species and Genetic Diversity
    This activity was developed for an undergraduate upper level ecology course for Environmental or Biological Science majors. Classes of ~20 students work best for the activity.
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    Choose Your Own Adventure: Control a Wildlife Disease Epidemic
    This educational game allows teams of students to try to control a simulated epidemic in United States snake populations using their epidemiological and ecological knowledge. It combines a "choose...

    Keywords: educational game

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    GEA Introductory lesson on RNA-Seq
    This RNA-Seq lesson uses the CyVerse VICE Platform and Jupyter notebooks to examine the expression of the leptin gene in samples from a mouse experimental design evaluating diet (high-fat vs....

    Keywords: data sciencebioinformaticsGenome BrowserRNAseqhigh throughput sequencingmRNAAlignmentNCBI Sequence Read Archive

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    Venom Diversity & Evolution in Reptiles and Amphibians - An education module for university students
    This module contains information for a three part series introducing the venom system in reptiles and discussing it in an evolutionary context. In the first part venom and its ecological roles are...

    Keywords: geneticsEvolutionecologyHerpetologyAmphibans and ReptilesVenom

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    Diseasebots
    This module explores the effects of host density on contact rates and transmission of pathogens or mutualist symbionts using a hands-on simulation, a computer agent-based model in NetLogo, and an...

    Keywords: NetLogoDisease ecologydensity dependenceSpreadsheethost-parasitemutualismOpen-inquiry group projectsmanipulative models (‘beanbag biology’)plotting

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    Riverbird distributions and habitat use
    Riverbirds are widespread, use diverse riparian habitats, and respond rapidly to changing conditions. Students can apply riverbird data to evaluate hypotheses about these responses, while gaining...

    Keywords: logistic regressionHabitat selectionRiver Field Studies NetworkWaterfowl raptorkingfisherheronfocal speciesmonitorriverbank

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    MathBench: Biodiversity Assessment of Stream Biota
    The MathBench module, "The Case of the Missing Mountaintop" introduces students to the concept of biodiversity and measures used to quantify biodiversity and stream health. Students investigate the...

    Keywords: ecology labCommunity Ecologyenvironmental scienceconservation ecologyStream ecology

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