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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Inquiry-based hypothesis testing using phylogenetic trees in MEGA
    A key learning objective in biology is applying bioinformatics tools to test a real-life question. These inquiry-based modules have students assemble and align data, and construct simple...

    Keywords: phylogeneticsbioinformaticsFASTANCBIBLASTmultiple sequence alignmentsequence similarityCourseSourceZika virusMEGAalcohol metabolism

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    Sequence Similarity: A Quick Introduction to Bioconductor
    Following the Sequence Similarity exercises by Kleinschmit, et al., this tutorial will guide students in using the Bioconductor suite of R packages to likewise compute sequence similarity.

    Keywords: bioinformaticssequencingNIBLSEmultiple sequence alignmentsequence similarityBLOSUM scoring matrixBioconductor

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    Macromolecular math
    This worksheet was developed for use in an introductory biology course to review the chemical bonds and structure of biological macromolecules. A nutritional label is provided to illustrate that...

    Keywords: introductory biologycarbohydratesProtein StructureNucleic Acid Structuremacromoleculesnon-covalent interactionpolypeptidechemical bonds

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    Oyster Restoration Success and Water Quality in the James and Rappahannock Rivers of Virginia
    This QUBES lesson uses statistical analysis to test whether or not oyster restoration sites in Virginia are successfully increasing the number of oysters and whether or not water quality is...

    Keywords: aquatic ecologymarine ecologyggplot2Pearson correlation coefficientSimple Linear RegressionnitrogenJames Rivertidyversechesapeake baywater qualityphosphorusharmful algae bloomsvirginia

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    Ingestion of Microplastics by Coral
    QUBES lesson on ingestion of microplastics by coral. Lesson will give environmental background and then use R for hands-on statistical analyses, followed by critical thinking questions.

    Keywords: statisticsRenvironmentmicroplastic pollutioncoralwilcoxon

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    A Little Off The Top: The Effects Of Mountiantop Removal Mining On Salamanders
    This lesson will provide an explanation of mountaintop removal mining, and potential harms associated with it. Then the lesson will move into a statistical analysis of salamanders living in streams...

    Keywords: ANOVAsalamandersalamandersmountaintopmining

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    Exploring global reef health and human population using correlation and simple linear regression
    In this lesson, students will explore the relationship between reef cover and human disturbance. Students will manipulate a large dataset and perform normality tests, data transformations,...

    Keywords: population dynamicshumanlinear regressionconservationcorrelationRestorationcoral reefs

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    Sizes, Scales and Specialization: Using Relative Proportions and Scientific Notation to Highlight the Diversity of Cell Types
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation.

    Keywords: ExponentsRatiosCellsqbccmanipulate equationsCellular and Molecular BiologyVisual Accommodationsconverting unitschanging scales

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    “Leveling Up” In Your Favorite Video Game Math Modeling Activity
    Students write linear equations that represent their model for solving a problem about playing video games.

    Keywords: modelingNIMBioslinear equationsmiddle grades (4-9)Middle SchoolSystems of Equations

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    Running the Same Pace During a Marathon
    This activity uses Algebra concepts for simple models using long distance running as an example.

    Keywords: NIMBiosAlgebraplottingSimple Equationsconverting unitsalgebra 1simple discrete equations

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    Regression: Tree Rings and Measuring Things
    Students develop scatter plots of growth rings by tree diameters and determine the equation of their best fit line.

    Keywords: NIMBiosregressiontree ringsline of best fit

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    Modeling an Ironman Race
    In this activity students create a model that represents an Ironman race.

    Keywords: NIMBiosgraphsAlgebraSimple Equationsalgebra 1simple modelssimple discrete equations

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    Fungus Among Us!
    This game introduces the idea of how fungi and plants can work together in a symbiotic relationship.

    Keywords: NIMBiosgraphingplantsfamily timeinformal science learningfungiinformal science educationsimple data plots

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    All About Cod For Grades 3-5
    This activity uses background from The Cod's Tale by Mark Kurlansky and then uses a simple story to engage students in solving problems using several operations and algebraic thinking math standards.

    Keywords: fishNIMBiosword problemsfractionsfish harvestinggrades 3-5simple data plots

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    All About Cod For Grade 2
    This activity uses data from The Cod's Tale by Mark Kurlansky to engage students in summarizing data in a table and bar graph.

    Keywords: fishNIMBiosBar GraphsGrade 2AdditionSubtractionword problemsfish harvestingsimple data plots

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    Electrical and chemical communication in the nervous system
    This activity guides students through an online tutorial to examine the electrical and chemical communication of neurons.

    Keywords: introductory biologyneurobiologyanatomy and physiologyCell communication

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    Climate-Induced Shifts in California Butterflies
    A module in which students generate and test hypotheses about butterfly species’ response to climate change in the Central Valley and Sierra Nevada Mountains of northern California using publicly...

    Keywords: linear regressionScatter Plotsclimate changephenologyhypothesis formulationmountainsCaliforniapublic dataCODAP

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    Yeti or not: Do they exist?
    Through this 4-part bioinformatics case study, students will be led through the forensic analysis of putative Yeti artifacts based on published findings.

    Keywords: case studybioinformaticsNIBLSEBLAST12S sequencingYeti

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    Investigating Evidence for Climate Change (Project EDDIE) with CO2 and 13CO2 data: adapted for R
    This is an adaptation to work in R of Investigating Evidence for Climate Change (Project) by Hage, M. 2020. Students will investigate geologic and modern evidence for global temperature and...

    Keywords: climate changeGlobal Temperature Changeco2ice core datastable isotopesR software

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    Is bigger always better? An investigation on the effect of drought on different sizes of trees
    This data set was compiled from worldwide data to examine the effects of drought on trees. Included in the dataset are measurements of growth and mortality as they relate to the size category of...

    Keywords: statisticsforest ecologydata analysisclimate changeANOVAGraphing Functionsforest health

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