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    Plants We Eat: Learning Form and Function from Fruits and Vegetables
    This high school or undergraduate lab consists of four activities that guide students through learning about plant parts from the fruits and vegetables with which they are already familiar....
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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    In this four- part guided activity, students will learn about the structure and function of human autosomal and sex chromosomes, view and interpret gene maps, and gain familiarity with basic...

    Keywords: bioinformaticsNIBLSECourseSourceautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

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    Analysis of Amylase Activity
    This lab is an exploration of enzyme function and the effects of environmental conditions on the activity of the enzyme amylase. The lab utilizes analytical and graphing skills to assess enzyme...

    Keywords: data analysisintroductory biologyconcentrationgraphinglinear equationsBiochemistryscientific methodstandard curveenzyme functionMicrosoft ExcelInterpreting GraphsenzymesqbccCreate graphsInterpret graphsSolving Equations and Inequalitiesinterpret tablesAmylaseAlpha-amylaseEnzyme activityMaltoseDNS assayAbsorbancelab reportspectrophotometryregression linemanipulating equationsline of best fitgraphing by hand

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    Introduction to Genome Annotation
    This exercise is an adaptation of the Annotation Lesson by Rosenwald et al. It introduces the use of bioinformatics tools to extract information from genome databases. It is a basic lesson on...

    Keywords: microbiologyGenome annotationBioinformatics EducationBioinformatics and Genomics

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    Keywords: bioinformaticsNIBLSEProtein StructureDNAmolecular modelinggenotypephenotypeCourseSourcecomputational modelingcentral dogmaplant leaf structure

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    Forests for the Future: How Can Trees Offset Carbon Emissions?
    This activity explores the chemistry and biology underlying forest carbon sequestration, a process that removes carbon from the atmosphere via photosynthesis and storage in plant tissues and soils....

    Keywords: carbon foot printCarbon sequestration of forests vegetationforest ecology (structure and function)

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    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    The Insect Predation Game: Evolving Prey Defenses and Predator Responses
    Laboratory experiment included in Teaching Issues and Experiments in Ecology (TIEE) Volume 4

    Keywords: simulationpredator-preypredation ecology

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    The Insect Predation Game: Evolving Prey Defenses and Predator Responses
    Laboratory experiment included in Teaching Issues and Experiments in Ecology (TIEE) Volume 4

    Keywords: simulationpredator-preypredation ecology

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    The Insect Predation Game: Evolving Prey Defenses and Predator Responses
    Laboratory experiment included in Teaching Issues and Experiments in Ecology (TIEE) Volume 4

    Keywords: simulationpredator-preypredation ecology

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    Using: "Winter Is Coming! Can you Handle the Freeze?" In an Intro BIO lecture
    I use Team Based Learning in this course, students are in permanent groups and work together on Challenge Questions each class after I give a short lecture. This Nugget was used in place of regular...

    Keywords: graphing

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    Sizes, Scales and Specialization: Using Relative Proportions and Scientific Notation to Highlight the Diversity of Cell Types
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation.

    Keywords: ExponentsRatiosCellsqbccmanipulate equationsCellular and Molecular BiologyVisual Accommodationsconverting unitschanging scales

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    Introduction to nucleotide sequence analysis and protein modeling in MEGA and PyMol using coronavirus SARS-CoV-2
    Introduction into computational approaches in phylogeny and protein modeling based on coronavirus SARS-CoV-2 (caused COVID-19 pandemic). Two self-guided tutorials for standard lab classes of 2.5...

    Keywords: phylogeneticsundergraduate educationbioinformaticsNCBICOVID19coronavirusMEGAPyMolvirtual labPDBprotein modelingSARSSARS-CoV

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    Louse and Human Coevolution
    This module examines the complicated co-evolution of Lice, Humans, and Great Apes

    Keywords: phylogeneticsBiodiversityparasitesCoevolutionhuman evolution

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    That Vertebrate Ate What Exactly?
    During the course of this lesson, students will analyze CT scan data and observe bycatch (or an unknown discovery) captured during the scanning process of vertebrates.

    Keywords: EvolutionidigbioAP Biologynatural history collections3D modelsanatomy and physiology#NGSSVertebrate MorphologyCT scanoVert

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    Movement: Nature's Flying Machines
    In this lab, you will explore the physics of flight, the adaptations that make powered flight possible, and the evolution of powered flight in vertebrates and invertebrates.

    Keywords: citizen sciencequantitative skillsDigital RepositoryFlight

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    Climate Change Effects on Lake Temperatures (Project EDDIE)
    Students explore new modeling and computing tools while learning fundamental concepts about how climate change will affect lakes

    Keywords: climate changeProject EDDIElakes

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    Hemoglobin bioinformatics
    This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

    Keywords: bioinformaticsHemoglobinBLASTsickle cell diseaseMolecular Case StudyClustal OmegaMolCaseNet

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    Caribbean coral reef structure and biodiversity - Comparing boosted regression tree & multiple regression approaches
    Creating and comparing boosted regression tree models to multiple regression models.
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