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    Enzyme Kinetics: How Quickly Can Acetylcholinesterase Break Up Your Thoughts?
    This module contains exercises designed to help upper-level cell biology students understand the common graphical methods used to evaluate enzyme activity and to see the impact of inhibitors on...

    Keywords: cell biologyQuantitative reasoninginterdisciplinarylinear modelsInterpreting GraphsNIQBC2. Data and GraphsC4. mathematical modelsnonlinear models

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    The Stomata Lab. What the past can tell us about our future - using fossil and modern plants to model atmospheric carbon dioxide
    Students will develop a mathematical model of the relationship between atmospheric CO2 and the number of stomata on a leaf (Stomata Index). They will evaluate the model graphically, statistically,...

    Keywords: introductory biologyQuantitative reasoninginterdisciplinaryclimate changeregressionEcology and EvolutionStomataNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical AnalysisSmithsonian

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    Cellular Respiration and pH: blocking the electron transport chain and its effects on the proton gradient, pH, and ATP production
    This module contains exercises designed to help students describe the stages of cellular respiration and quantify the energy molecules produced. Students will predict the region of higher proton...

    Keywords: introductory biologyQuantitative reasoningquantitative biologyinterdisciplarycell functionInterpreting GraphsATPpHCellular RespirationEnergy transformationsElectron flowNIQBC2. Data and GraphsC4. mathematical modelsC1. Numeracyproton gradientelectron transportelectron transport blockersFADH2chemiosmosisATP synthaseNADHproton concentration

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    Osmosis: Determination of the rate of osmosis and the isotonic concentration
    This module contains exercises designed to help students understand how solute concentrations affect the direction and rate of osmosis. Students are given different scenarios to predict the...

    Keywords: introductory biologyQuantitative reasoninginterdisciplinarycell functionOsmosisNIQBC2. Data and GraphsC4. mathematical modelsC6. Quantitative LanguageC1. NumeracyC5. Logic and Algorithms

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    Cell Cycle and Mitosis
    This module introduces activities that allow students to walk through the cell cycle and mitotic cell division processes. As part of the activities, students learn about and apply knowledge of...

    Keywords: introductory biologyQuantitative reasoningInterdisciplinary STEMquantitative biologyinterdisciplinaryquantitative skillscell functioncell cyclemitosisCell DivisionMitotic Indexcalculating meanstumorNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical Analysisstandard errormitotic phaseinterphase

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    RAT ATTACK! Population growth
    This module contains exercises focused on the use and interpretation of density independent and density dependent population growth models. Students build logistic and exponential growth models in...

    Keywords: modelingecologyExcelintroductory biologygraphingQuantitative reasoningdata visualizationinterdisciplinaryexponential growthlogistic growthdata managementInterpreting Graphspopulation modelingNIQBC2. Data and GraphsC4. mathematical modelsnonlinear models

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    Hidden Markov Model
    Hidden Markov models are a set of mathematical tools that can be used to draw inferences about genomic and evolutionary processes.

    Keywords: hidden markov models

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    Bioinformatics / Neuroinformatics
    This module is a computer-based introduction to bioinformatics resources.  This easy-to-adopt module weaves together several important bioinformatic tools so students can grasp how each is used in...

    Keywords: bioinformaticsNIBLSEImageJquantitative trait locusQTL

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    Kinetics of a Highly Conserved Enzyme - Carbonic Anhydrase
    This module contains exercises designed to introduce students to graphical representation of biological data. Students will explore the fundamental principles of enzyme kinetics including...

    Keywords: Excelintroductory biologycell biologygraphingslopeQuantitative reasoningdata visualizationquantitative biologyinterdisciplaryquantitative skillscorrelationenzyme functionInterpreting GraphsMichaelis-Mentenenzyme kineticsEnzyme activityenzyme inhibitionLinear and nonlinear analysisNIQBC2. Data and GraphsC4. mathematical modelsenzyme-substrateNIQB Interdisciplinary Quantitative Reasoningcarbonic anhydrase

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    Using the Hardy-Weinberg Equations: Quantifying Natural Selection and Allele Frequencies
    This module contains exercises designed to walk students through a real-world example of the coevolution of fruit color and primate frugivore color vision. Students will apply the Hardy-Weinberg...

    Keywords: Hardy-WeinbergEvolutionintroductory biologyQuantitative reasoninginterdisciplinaryNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical AnalysisC6. Quantitative LanguageC1. Numeracy

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    Modeling: A Primer - The crafty art of making, exploring, extending, transforming, tweaking, bending, disassembling, questioning, and breaking models
    Explore how to use, analyze, and criticize some important and historically influential models in biology in this text only module.

    Keywords: modelingsimulationmoduleResources @ BioQUESTtextbookmodulesmathematical modeling

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    Discrete Math Modeling with Biological Applications (Course Materials)
    These are the materials for Math 214 offered at Rhodes College.

    Keywords: labsagent-based modelingDiscrete Difference Equationsmatrix modelscoursebiomath coursedemonstrationin-class activitylab protocolproblem set

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    Genome Solver: Complete Set of Lessons
    The Genome Solver Project began as a way to teach faculty some basic skills in bioinformatics - no coding or scripting. These Lessons also work well in the undergraduate classroom, culminating...

    Keywords: bioinformaticsNIBLSEBioinformatics EducationBioinformatics and GenomicsC4. Bioinformatics toolsC5. Data retrievalC6. ModelsC8. Data typesC9. ImplicationsRecommended by NIBLSE

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    COVID-19 Simulator (ISEE) Module
    This accessible module guides students through exploring the COVID-19 Simulator developed by ISEE. Students dig into the four scenarios provided (including the parameters and the graphs),...

    Keywords: mathematical modelingSTELLAInfectious Disease ModelingInterpreting Graphsinterpreting modelsCOVID19coronavirus

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    Keywords: bioinformaticsNIBLSEProtein StructureDNAmolecular modelinggenotypephenotypeCourseSourcecomputational modelingcentral dogmaplant leaf structure

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    Behavioral Genetics: Investigating the genes of a complex phenotype in fruit flies
    Introductory genetics laboratory published as GSA Learning Resource

    Keywords: behaviorbioinformaticsNIBLSEdrosophilagenetic basisfruit fliesmodel organism

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    MathBench Population Dynamics Module Activity
    The resource accompanies the Mystery of the Missing Housefly Population Dynamics MathBench module which explores exponential and logistic growth models. Students explore the assumptions of the...
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    Sequence Similarity: Introducing Biological Databases to Community College Biology Students
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    Developing a phylogram from computational resources.
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityneighbor-joining distance matrixCourseSourcephylogrampercent identity matrix

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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