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    Data Analysis and Cancer
    This is a flipped classroom approach, students will learn the basic content about cell-signaling, p53, and transcription factors before class. During class students will focus on data analysis...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologydata interpretationBiological Data Analysiscell cyclemacromoleculesGenetic diseaseCell signaling

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    Mol* Adaptation: Case of Severe Insulin Resistance
    This is an adaptation using Mol* on the original case written. This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to...

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistanceMol*MolStar

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    A Case of Severe Insulin Resistance
    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistance

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    Regulation of Gene Expression and Adipogenesis by PPAR-γ
    Students learn about transcriptional regulation of PPAR-γ, an important controller of adipose tissue stores and energy metabolism through a drawing/coloring activity of the different components...

    Keywords: gene expressionsmall group worktranscriptional regulationadipose tissuefat metabolismrepressor

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    Mechanisms of Cell Attachment
    This module introduces the calculation of refractive indices along a cell surface in the context of understanding the attachment of cells to surfaces. It is intended for an introductory biology...

    Keywords: GeometryCell StructureCell GrowthSimple EquationsInterpreting GraphCell Attachment

    850

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    Maintenance of Cell Shape
    This module introduces an equation to calculate roundness in the context of understanding how myosin contributes to cell shape. It is intended for an introductory biology audience.

    Keywords: AlgebraCell StructureCell Growthbar chart

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    Cell Aggregation and Sphere Packing
    This module introduces the calculation of packing density in the context of understanding cell aggregation and arrangement. It is intended for an introductory biology audience.

    Keywords: RatiosGeometryInequalitiesCell StructureCell GrowthCell AggregationSphere Packing

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    Cell Division and Rates of Population Growth
    This module introduces the exponential growth of cells in the context of understanding cell division. It is intended for an introductory biology audience.

    Keywords: exponential equationscell growth and divisionGeometric SeriesCell StructureOpenStaxgeometric equations

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    Doubling Time of Tumors
    This module introduces the calculation of potential doubling time of tumorous cells in the context of understanding the growth of a population of the cells. It is intended for an introductory...

    Keywords: linear regressionRatiosCell StructureOpenStaxCell Growth

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    Mitotic Index and Cell Division
    This module introduces the mitotic index in the context of understanding the dynamics of cell division in the root of a plant. It is intended for an introductory biology audience.

    Keywords: RatiosCell StructureCell GrowthchartCell DivisionMitotic Index

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    Nucleoplasmic Index
    This module introduces the nucleoplasmic index in the context of understanding how the volume of organelles and cell contents change during the cell cycle. It is intended for an introductory...

    Keywords: RatiosInterpreting GraphsCell StructureCell GrowthNucleoplasmic Index

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    Sizes, Scales and Specialization: Adapted to add scientific notation review
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation. The adaptation has...

    Keywords: ExponentsRatiosScientific Notationcell typeqbccmanipulate equationsCellular and Molecular Biologyconverting unitschanging scales

    1086

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    Sizes, Scales and Specialization: Using Relative Proportions and Scientific Notation to Highlight the Diversity of Cell Types
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation.

    Keywords: ExponentsRatiosCellsqbccmanipulate equationsCellular and Molecular BiologyVisual Accommodationsconverting unitschanging scales

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    Sickle Cell Disease and Natural Selection in Humans
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Serial Dilutions
    In this Excel workbook, users will enter the original cell concentration and the desired dilution factor (10, 100, and 1000). The program will then calculate the new cell concentration.

    Keywords: concentrationScientific Notationorders of magnitudeserial dilutions

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    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Cell Division and the Presence of a Growth Factor
    This module introduces exponential growth, the Michaelis-Menten, and Lineweaver-Burk equations in the context of understanding how growth factors influence cell division. It is intended for an...

    Keywords: exponential equationshyperbolic equationsCell StructureCell Growthgrowth factor

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    Permeability of Molecules
    This module introduces Overton's Rule in the context of understanding the permeability of molecules across the cell membrane. It is intended for an introductory biology audience.

    Keywords: linear regressionPermeabilityCell StructureCell MembraneOpenStaxphospholipid membranelog-log plotsOverton's rule

    1054

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    213

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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