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    When tests disagree, how do I know if I have COVID-19?
    Students will learn about infectious disease and the immune response to infection by investigating different types of tests (PCR, antigen, and antibody tests) to detect the SARS-CoV-2 viral genetic...

    Keywords: geneticsVision and Changeintroductory biologyinfectious diseasemolecular biologycore competenciesRT-PCRviruscore conceptsnon-majors biologySARS-CoV-2antibodyAntigenImmunoReachmolecular DiagnosticsCOVID-19 transmission

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    EvolSeq
    An Excel worksheet that simulates the molecular evolution of DNA sequences.

    Keywords: molecular evolutionDNA

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    Understanding COVID-19 Biology to Design a Vaccine - Ethics supplement
    The adaptation to Understanding COVID-19 Biology to Design a Vaccine entails two ethics supplements. The first supplement addresses the use of off-label drugs in the pandemic (or other situation)....

    Keywords: bioethicsBLASTprotein structure modelingmolecular visualization and analysisethicsCOVID19PDB

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    Hemoglobin Evolution
    This module introduces equations describing blood viscosity and oxygen transport in the context of understanding the evolution of red blood cells. It is intended for an introductory biology audience.

    Keywords: calculushyperbolic equationsAnimal Physiologyparabolic equationsmaxima

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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Phylogeny of Land Plants
    In this lab, students review the characteristics of the major land plant lineages. Then they perform phylogenetic analyses based on morphological characters.

    Keywords: morphologyphylogenylaboratoryplantsmolecular analysis

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    "What's on your plate?" with Adam Cornish, PhD
    This talk delves into “Modern Agriculture: What’s on Your Plate?” with Dr. Adam Cornish. Adam is a program analyst in the Office of Agricultural Policy at the State Department, and received his...

    Keywords: agriculturePublic PolicyGMOs

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    Creating Phylogenetic Trees from DNA Sequences
    This interactive module shows how DNA sequences can be used to infer evolutionary relationships among organisms and represent them as phylogenetic trees.

    Keywords: EvolutionHHMI BioInteractivephylogenetic tree

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    When did I lose my legs? A limbless lizard tale
    Using oVERT project models students examine examples of extant traditional lizards, snakes and limbless lizards and create phylogenies based on trait and genetic data.

    Keywords: phylogeneticsevolutionary biologyHerpetologynatural history collections3D models#NGSSdigitized natural history collectionsoVertConvergent Evolution

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    Joel E. Greengiant Learns About Peas: From Nucleotides to Selection
    This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet (wrinkled) peas, all in...

    Keywords: geneticspopulation geneticsEvolutionintroductory biologycase studybiologyResources @ NSF - NCCSTSmeiosisMendel’s peaspea plantPisum sativumMendel’s Lawsmolecular geneticsmutationnucleotide insertionartificial selectionstarch synthesisstarch branching enzymeplant domesticationlegumesResources @ QUBES - Teaching & Reference

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    Hemoglobin bioinformatics
    This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

    Keywords: bioinformaticsHemoglobinBLASTsickle cell diseaseMolecular Case StudyClustal OmegaMolCaseNet

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    Origin and Diversity of Armor in Girdled Lizards
    The girdled lizards (Cordylidae) are a family of distinctively armored lizards endemic to Sub-Saharan Africa. Students examine lizards in this family to classify the lizards based on morphological...

    Keywords: Evolutionphylogenetic analysisHerpetologynatural history collections3D modelsVertebrate MorphologyCT scanoVertConvergent Evolution

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    Amino Acid Frequency
    This module introduces expected frequencies in the context of understanding amino acid composition. It is intended for an introductory biology audience.

    Keywords: Probabilitylinear regressionamino acidsOpenStaxGenetic InformationAminoAmino Acid Freuency

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    Monkey Opsins
    This case will examine the evolution of trichromatic vision in old world monkeys.

    Keywords: modulephylogeneticsecologycell biologymolecular geneticsResources @ EvoEd

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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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    Discovering biodiversity in Honduras with TJ Firneno
    TJ talks to us about the different types of biodiversity, why they are important, and about his research involving the discovery of a new species of microhylid in Honduras! If you or your students...

    Keywords: geneticsmorphologyBiodiversitytaxonomyamphibians

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    Going from student to medical doctor. The pathway to medicine with Abel Edossa and Dr. Oluwatoyin Weaver
    In this "lunch with a Scientist" episode, we interviewed a medical student and medical doctor to help us understand the path to medicine. Becoming a medical doctor is a very daunting task but with...

    Keywords: medicine

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    Why are Cells Small? Surface Area to Volume Ratio
    This module explores surface area to volume ratios in a cube and sphere in relation to cell size.

    Keywords: introductory biologygraphingRatiosOpenStaxqbccmanipulate equationsCellular and Molecular BiologyUse elementary functionsCreate graphsInterpret graphsRates and ProportionsSolving Equations and Inequalitiesinterpret tables

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    Sequence Similarity: Introducing Biological Databases to Community College Biology Students
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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