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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    Operon
    This Excel workbook models lac operon function in a partial diploid E. coli. The user chooses the bacterial genotype and the sugars present in the surrounding medium: the workbook then determines...

    Keywords: Lac OperonE. coli

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    In silico chromosome mapping: Idiograms
    This workbook allows the user to construct idiograms (haploid or diploid), map sequences onto them, depict chromosome structural mutations, and perform side-by-side comparative analyses of...

    Keywords: InheritancemutationschromosomesidiogramDrosophila melanogaster

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    ABO Blood Group Frequencies
    An Excel workbook in which students can calculate blood type frequencies through different approaches (Hardy-Weinberg, quadratic formula, and the EM algorithm). The workbook shows the formulas...

    Keywords: Hardy-Weinbergblood type frequencies

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    3D FractaL-Tree
    3D FractaL-Tree allows scientists to collect data from actual specimens in the field or laboratory, insert these measurements into a spatially explicit L-system package, and then visually compare...

    Keywords: fractalsL-systems

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    Interpreting the Pseudocot Phylogeny
    Students use physical characteristics, genetics, and a fossil record of hypothetical flowering plants to develop fundamental phylogenetic tree-building skills.
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    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    The Mathematics of Voting Systems: Plurality, Runoff and Ranked Choice
    In this five-day interdisciplinary math and social studies unit, students use math to create informed opinions about the three most common voting systems in the United States: plurality, runoff and...

    Keywords: mathematicsInterdisciplinary STEMInterdisciplinary Mathematics Educationinterdisciplinary math educationvoting

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    A STEAM Approach to Investigating the Hydrologic Cycle
    The purpose of this experiential lesson is to teach introductory to mid-level undergraduate students how to make detailed hydrologic field observations into a conceptual model using a painting...

    Keywords: modelinghydrologyfield-based learningSTEAM curriculumhydrogeologyhydrologic cycle

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    Keywords: bioinformaticsNIBLSEProtein StructureDNAmolecular modelinggenotypephenotypeCourseSourcecomputational modelingcentral dogmaplant leaf structure

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    Prairie Eco Services (Project EDDIE)
    As densely populated urban areas continue to expand, human activity is removing much-needed greenspaces from our communities; in turn, we are also removing critical buffers that are needed to...

    Keywords: Project EDDIEWater cycle

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    The nose knows: How tri-trophic interactions and natural history shape bird foraging behavior
    Students investigate the role of olfaction and infochemicals on bird foraging behavior through three different quantitative modules. In this module students create graphs, generate statistics, draw...

    Keywords: Resources @ ESA - TIEEforagingfmnbehavioral ecologyDIGtrophic cascadesAntarctic foodd webs

    2929

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    That Vertebrate Ate What Exactly?
    During the course of this lesson, students will analyze CT scan data and observe bycatch (or an unknown discovery) captured during the scanning process of vertebrates.

    Keywords: EvolutionidigbioAP Biologynatural history collections3D modelsanatomy and physiology#NGSSVertebrate MorphologyCT scanoVert

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