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    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...

    Keywords: developmenttranscriptiongene expressionmodel organismembryo

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the...

    Keywords: BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix

    2019

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    640

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    A Team-Based Approach to Course Development Involving Undergraduate Researchers
    Development of an undergraduate laboratory course can be a challenge, because of the need to balance both logistical and pedagogical considerations. We piloted a team-based approach to developing...

    Keywords: student researchcourse development

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological...

    Keywords: protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular

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    Visualization: Quantitative reasoning via image analysis, networks, topology, generative models, and 3D rendering
    Resource from the 2015 BioQUEST Summer Workshop
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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs...

    Keywords: fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills

    1968

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    505

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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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    Learn Biological Sciences and Chemistry through cellular transport and concentration ( online and hands-on)
    Osmosis is a process by which by which solvent move from a region of lower solute concentration to region of higher solute concentration through a semi-permeable membrane. Cells utilize the process...

    Keywords: statisticsdata analysisbiologycell biologyconcentrationskillscellchemistryOsmosisSpectrophotometersolutionsolutesolvent

    414

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    Using Regression Models to Examine the Effect of Carbon Dioxide on Fluid pH
    In this activity students will use statistics and regression models to explore the effects of carbon dioxide on blood pH by measuring pH changes that occur over time as carbon dioxide reacts with...

    Keywords: BiochemistryphysiologyAnatomyGeneral BiologyChoosing modelsCreate graphsInterpret graphsConcepts in Statisticscreate modelsmake predictions

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    Teaching Modules from QB@CC: Tools to Improve Biology Student’s Quantitative Skills
    NABT and QB@CC hosted a special webinar to explore the QB@CC OER entitled Sizes, Scales, and Specialization.

    Keywords: NABTPresentationworkshopqbcc

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    Immunity and Vaccine Action
    From the cellular level on up, being aware of your interactions can help you stay safe. This resource addresses fundamental immunology and infectious disease concepts through a historical...

    Keywords: immunology educationvaccine literacyvaccine hesitancy

    272

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    Uninhibited Growth of Cells
    In this activity, students will explore the concept of binary fission, generation time, and bacterial growth curves, with an emphasis on the log phase. Students will use semi-log graphs and linear...

    Keywords: graphingexponential growthMicrobiology Educationmicrobiologybacteriagrowth rateUndergraduate STEM educationCommunity College Educationqbccmanipulate equationsCellular and Molecular BiologyCreate graphsInterpret graphsbinary fissionsemi-log graphlinear graphgrowth curvecreating graphsExponential and Logarithmic Functions

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    Water Movement through a Membrane: The Van't Hoff Equation
    This module introduces the van't Hoff equation in the context of understanding the metabolic activity of the epithelial cells lining the stomach. It is intended for an introductory biology audience.

    Keywords: AlgebraInequalitiesCellular Processes

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    Regulation Across Scales: Data Points Icebreaker Jigsaw
    Students examine regulation at cellular, physiological, and ecological scales in a data-based jigsaw to explore how double-negative logic operates across biological systems. This was used as a...

    Keywords: pathwaysgene regulationtrophic cascadesregulationcross-scalecholesterol synthesisLac OperonYellowstone

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    Regulation Across Scales: Data Points on How Life Works
    We examined the scientific literature for simple, data-based illustrations of double-negative logic in the regulation of biological systems as described by Sean B. Carroll in his text, The...
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    BioNumbers: The Database of Useful Biological Numbers
    A database of biological numbers that you can search and browse.
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    Cancer Discovery Activities
    These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video (http://www.hhmi.org/biointeractive/cancer-genetic-disease-video-highlights)...

    Keywords: geneticsResources @ HHMI - BioInteractiveorganismal biologyneurosciencegenomicscancergenetic basis of diseasebiology of cellsHigh School

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    RNA-seq Analysis
    In this computer lab module, students learn how to process an RNA-seq data set to identify differentially expressed genes (DEGs). The samples for this data set were collected from yeast cells...

    Keywords: LabRNAsequencingUndergraduateNIBLSEincubatorsRNAseqInstructional SettingAudience LevelActivity LengthMore than 1 hourC4. Bioinformatics toolsC5. Data retrievalReviewed at NIBLSEdifferentially expressed genes

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    Introduction to Climate Change: Why we should care
    In this lesson, students cover the basics of climate change, interpret and predict several graphs that explain climate change scenarios under different treatment options, and reflect on an...

    Keywords: graph interpretationclimate changePlant Ecologyfmndata literacyBioGraphIrepresentation in STEMNon Majors Intro Biosand dunes

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    Defenses against predation: Interpreting graphs of predator behavior
    In this lesson, students discuss anti-predator defense mechanisms and the types of cues defenses provide to predators. Students then interpret graphs of behavior of arthropod predators when...

    Keywords: graph interpretationfmndata literacyinterspecific interactionsconsumptionBioGraphIrepresentation in STEMarthropodsaposematismphenotypic variationtortoise beetlecarton-nest antspraying mantisorb-weaving spider

    519

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