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    Responses to Climate Change in California Chipmunks: Move, Adapt, or Die
    A series of three modules using data from natural history museum collections to examine responses to climate change in multiple chipmunk species. Elevation and morphological data, beginner skills...

    Keywords: statisticsmodelingmodulemorphologysummary statisticsmodulesclimate datamuseumsclimate changeundergraduate educationR programming languageprogrammingelevationnatural history museumsmammalssmall mammals community dynamicsmuseum collectionsVertebrate Morphologyopen educational resourceR programming environment

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    Introduction to Genome Annotation
    This exercise is an adaptation of the Annotation Lesson by Rosenwald et al. It introduces the use of bioinformatics tools to extract information from genome databases. It is a basic lesson on...

    Keywords: microbiologyGenome annotationBioinformatics EducationBioinformatics and Genomics

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    REMNet Tutorial, Excel Part 3: Organizing Your Microbiome Data 5.3.19
    Video on organizing microbiome using Excel from the Research Experiences in Microbiomes Network

    Keywords: ExcelVideoMicrobiology Educationmicrobiomesresearch in the classroomREMNeturban microbiomes

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    Teaching introductory bioinformatics with Jupyter notebook-based active learning
    Presentation on teaching introductory bioinformatics with Jupyter notebook-based active learning at the 2019 Great Lakes Bioinformatics Conference

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Build-a-Phage Lab Manual
    This is a lab manual for phage genome synthesis that includes both Building Block synthesis and Semi-synthetic assembly.
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    Aquatic Nutrient Levels and Climate Change
    This learning module was designed to introduce students to the aquatic nutrients nitrogen and phosphorus, their roles in ecosystem function and nutrient pollution, and what impacts climate change...

    Keywords: climate changenitrogenwater resourcesfreshwater systemsEutrophicationwater qualitynutrient pollutionphosphorusdischargeTMDL

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

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    Cystic Fibrosis Mechanism and Treatment
    This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymacromoleculesGenetic diseaseCell Structure & Function

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    Adaptation of Investigating human impacts on stream ecology: locally and nationally
    TIEE Module- How does nutrient pollution impact stream ecosystems locally and nationally?
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    Movement: Nature's Flying Machines
    In this lab, you will explore the physics of flight, the adaptations that make powered flight possible, and the evolution of powered flight in vertebrates and invertebrates.

    Keywords: citizen sciencequantitative skillsDigital RepositoryFlight

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    AVIDA exercise on the role of mutation in evolution
    A tested exercise at the college freshmen level using AVIDA-Ed to generate and test a hypothesis about the relationship between mutation rate and the probability of evolving a useful function in...
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    Amylase Copy Number and Diet
    An adapted module from HHMI Spreadsheet Tutorials using amylase data for students to gain data analysis and excel skills

    Keywords: Scientific ProcessStatistics and MathScientific Methodology

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    Spider Silk: Stress-Strain Curves and Young's Modulus
    This module introduces the stress-strain curve in the context of understanding materials' mechanical behavior. It is intended for an introductory biology audience.

    Keywords: structurestressbiomechanicsFunctionsstrainYoung's Modulusmechanical

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    Exploring the functionality of R
    Students work with example data to generate a length-weight plot and use lm() to obtain regression coefficients. Base plot functions are used to plot both the data and the regression line.
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    Regulation of Gene Expression and Adipogenesis by PPAR-γ
    Students learn about transcriptional regulation of PPAR-γ, an important controller of adipose tissue stores and energy metabolism through a drawing/coloring activity of the different components...

    Keywords: gene expressionsmall group worktranscriptional regulationadipose tissuefat metabolismrepressor

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    Keywords: bioinformaticsNIBLSEProtein StructureDNAmolecular modelinggenotypephenotypeCourseSourcecomputational modelingcentral dogmaplant leaf structure

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    In this four- part guided activity, students will learn about the structure and function of human autosomal and sex chromosomes, view and interpret gene maps, and gain familiarity with basic...

    Keywords: bioinformaticsNIBLSECourseSourceautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

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    Finding Selection in All the Right Places
    Lab introducing students to evolutionary genetics using bioinformatics and biocuration, published as GSA Learning Resource

    Keywords: geneticsbioinformaticssequencingNIBLSE

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    Seed Dispersal in Tropical Forests: Learning How Plants Move Around
    This module focuses on the dispersal of seeds from trees in fragmented tropical forests. Students use data from published studies to understand patterns of seed dispersal and apply these ideas to...

    Keywords: ecologyResources @ HHMI - BioInteractivecommunityplantsdiversityScientific Process

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    Food Chain Dynamics In A Simple Ecosystem
    In this lab, students will work with a simple algae/brine shrimp environment to learn about food chains and population dynamics.

    Keywords: ecologyecosystemsfood chainalgae

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