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    Module 4: Removal of Introns from pre-mRNA by Splicing
    In this module, students will learn to identify splice donor and acceptor sites that are best supported by RNA-Seq data, and use the canonical splice donor and splice acceptor sequences to identify...

    Keywords: geneticsdata visualizationmolecular biologygenomicsexonintronsplicingSimilarity searchesRNA Maturation

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    Module 3: Transcription, Part II: What Happens to the Initial Transcript Made by RNA pol II?
    This module teaches about the three key steps that are involved in converting the pre-mRNA into a mature mRNA: 1) The addition of a 5’ cap, 2) The addition of a 3’ poly(A) tail, 3) The removal of...

    Keywords: geneticsmolecular biologyGenome BrowsergenomicssplicingmRNAcDNA5' Cap3' Poly(A) TailRNA Maturation

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    DNA and Knot Theory
    This module introduces knot theory in the context of understanding the packing of DNA. It is intended for an introductory biology audience.

    Keywords: DNAGenetic InformationTopologyKnot Theory

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    A clicker-based case study that untangles student thinking about the processes in the central dogma
    The central dogma of biology is a foundational concept that provides a scaffold to understand how genetic information flows in biological systems. Despite its importance, undergraduate students...

    Keywords: mutationtranscriptionphenotypecentral dogmatranslationDNA replication

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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    Keywords: transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

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    Mock Drug Activity Enhances Student Learning About the Challenges of HIV/AIDS Therapy
    While traditional didactic coursework is important for learning about the scientific aspects of HIV/AIDS, it is difficult to convey social aspects of the epidemic. Due to effective drug therapies,...

    Keywords: drug resistanceRetrovirusViral replication

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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics...

    Keywords: longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics

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    2014-Chivers-EtAl-Predator-prey systems depend on a prey refuge
    We present an agent-based model which does not require the factors or constraints of previous models to reproduce all six patterns in persistent populations.

    Keywords: Individual & Agent Based Modelingpredator-preythink-pair-shareslynxrefugeprey switchingMustela-Clethrionomys systempatter oriented

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    Why representation matters: Interpreting data to identify factors that affect Black students’ persistence in STEM
    In this lesson, learners interpret a table summarizing the factors influencing the persistence of Black students at an HBCU. Then, learners view and reflect on an interview with science education...

    Keywords: biologydata interpretationhbcuSelf-EfficacyBioGraphIrepresentation in STEM#BIPOCinSTEMBlack representation in STEM

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    Hypoxia: A Case Study in R
    Aquatic ecosystems are home to a complex intersection of physical and biological factors and an intersection of natural and anthropogenic factors. In the Chesapeake Bay, low oxygen events have...

    Keywords: data analysisOceanographyProject EDDIE

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    Have fish assemblages recovered from the legacy of acid rain?
    This module provides a framework for upper-level ecology students to learn about limiting factors for stream fish diversity, using data from Shenandoah National Park and gaining skills in...

    Keywords: Problem based learningdiversitycooperative learninglimiting factorsaquatic ecosystemspyramid examlab reports

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    Investigating Leaf Litter Decomposition and Invertebrate Communities in Streams
    Students utilize the provided dataset to engage in an open-inquiry project on the impacts of abiotic and biotic factors on stream macroinvertebrate communities and/or leaf litter decomposition.

    Keywords: Resources @ ESA - TIEEInvasive SpeciesfmnDIGspecies tolerance curvesdiversity indiceslitter decomposition ratesfreshwater ecologyopen-inquiry

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    Where Does Elsie's Hair Color Come From? A "De-Simplified" Pedigree Lesson
    Pedigree analysis is part of most Genetics curricula, but the examples traditionally used in genetics courses present phenotypes as if they were entirely and inexorably defined by genotype. This...

    Keywords: pedigreeMultifactorialphenotypic variationpenetranceexpressivityquantitative variation

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    The Three Sisters of Agriculture: An Active Learning Activity on Symbiotic Nitrogen Fixation
    This active learning exercise introduces students to the plant microbiome and the contributions that bacteria make to plant growth and food production. The Three Sisters are an ancient indigenous...

    Keywords: SymbiosisPlant microbiomeNitrogen fixationNutritional content of foodElectron flowSociety impact of microorganisms

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    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing...

    Keywords: genomicstranscriptionsignaling

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    2018-David_Bourne-Pharmacokinetics – Source Material
    This is a rich source of pharmacokinetics modeling activities and data. These are syllabus notes with homework assignments listed.

    Keywords: boluspharmacokineticspharmacodynamicdrug distribution

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    1-083-FallingMeteorites-ModelingScenario
    After introducing the solution to the ordinary differential equation which models a falling object with drag (first-order, non-linear, separable), students will consider generalizing the model to a...

    Keywords: falling objectdragvariable massfactor rankingmeteormeteorite

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    Sustainability Metrics (Project EDDIE)
    In this module, students will use an analytical framework with publicly available data to formulate questions, analyze data, and report metrics of sustainability.

    Keywords: World Geography

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    Sustainability Metrics (Project EDDIE)
    In this module, students will use an analytical framework with publicly available data to formulate questions, analyze data, and report metrics of sustainability.
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    Sustainability Metrics (Project EDDIE)
    In this module, students will use an analytical framework with publicly available data to formulate questions, analyze data, and report metrics of sustainability.
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