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    Electrical Activity of Neurons
    This tutorial describes how neurons generate action potentials, and how scientists measure neuronal activity and record the firing of individual neurons.

    Keywords: Resources @ HHMI - BioInteractiveAnatomy & PhysiologyNervous systemCell communication

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    Do Cell Phones Cause Brain Tumors?
    This YouTube video talks about whether there is a causal relationship between cellphone usage and brain cancer.

    Keywords: Presentation

    697

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    The Evolution of Color Vision in Monkeys: From Nucleotides to Ecology
    This case study examines the evolution color vision in Old World and New World monkeys from multiple biological perspectives.

    Keywords: phylogeneticsgenescase studybiologyResources @ NSF - NCCSTSColor visiondichromatictrichromaticnucleotidesproteinsopsinscell functioncone cellsphotoreceptorsspectral shiftgene duplicationmeiosissex-linkedfood gatheringmonkeysprimatesResources @ QUBES - Teaching & Referenceundergraduate biology education

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    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...

    Keywords: developmenttranscriptiongene expressionmodel organismembryo

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    306

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs...

    Keywords: fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills

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    Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?
    One of the challenges of teaching Cell Biology is helping students understand important research methods used to study cells.  The goal of understanding cell biology methods is especially...

    Keywords: ABC transporter familyDifferential centrifugationImmunoblottingImmunofluorescence assayProtein localizationPurifying organellesSDS-PAGE

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    Teaching Modules from QB@CC: Tools to Improve Biology Student’s Quantitative Skills
    NABT and QB@CC hosted a special webinar to explore the QB@CC OER entitled Sizes, Scales, and Specialization.

    Keywords: NABTPresentationworkshopqbcc

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    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer...

    Keywords: cancertumorfittingagent-based

    116

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    Cell ploidy made simple: Resources for students and instructors
    The concept of cell ploidy can be challenging for students to grasp. This resource includes a short, informal instructional video and a worksheet/set of clicker questions combo that allows students...

    Keywords: meiosismitosis1n2nploidyhaploiddiploid

    232

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    3-D Printing Models of Cell Organelles and Flowers
    This hands-on module features active learning using 3-D printing technology to teach middle school students about physical scientific models and cell organelles.
    699

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    Module 4: Removal of Introns from pre-mRNA by Splicing
    In this module, students will learn to identify splice donor and acceptor sites that are best supported by RNA-Seq data, and use the canonical splice donor and splice acceptor sequences to identify...

    Keywords: geneticsdata visualizationmolecular biologygenomicsexonintronsplicingSimilarity searchesRNA Maturation

    1097

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

    3261

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    Translocation of Nutrients in the Phloem: Poiseuille's Equation
    This module introduces the Poiseuille equation in the context of understanding nutrient flow in plant cells. It is intended for an introductory biology audience.

    Keywords: plant physiologycalculushyperbolic equationsrates of change

    1075

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    197

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    Gibb’s Free Energy and the Nature of Chemical Reactions
    This module introduces Gibb’s Free Energy in the context of understanding the nature of chemical reactions. It is intended for an introductory biology audience.

    Keywords: ExponentsLogarithmsRatiosexponential equationsSequencesCell StructureOpenStaxCell Growthgeometric equations

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    Monkey Opsins
    This case will examine the evolution of trichromatic vision in old world monkeys.

    Keywords: modulephylogeneticsecologycell biologymolecular geneticsResources @ EvoEd

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    Calculating Lifetime Cancer Risk Resulting from DNA Replication
    An expanded case study adapted from an HHMI Data Point on Cell Division and Cancer Risk using Figure 1 from Tomasetti, C. and Vogelstein, B. (2015).

    Keywords: cancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

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    A Structured Inquiry-Based Module for the Undergraduate Cell Biology Laboratory That Teaches Fundamental Concepts of Cell Differentiation
    Pedagogical research in science education has shown that students effectively learn science by doing science. As a result, there is increased interest in bringing research-like experiences into the...

    Keywords: fluorescence microscopygene expressionpolymerase chain reactionCell Structurecell culturewestern blottingdifferentiationreverse transcription

    563

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    Cell Signaling Pathways - a Case Study Approach
    Signaling and gene expression are fundamental to cell biology and developmental biology. Although these topics are highly interrelated, they typically appear in separate units in a course. We use a...

    Keywords: signal transductiongene expressionCell communicationgenetic disordersregulation of enzyme activity

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    Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms
    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...

    Keywords: mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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