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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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    Investigating the Function of a Transport Protein: Where is ABCB6 Located in Human Cells?
    One of the challenges of teaching Cell Biology is helping students understand important research methods used to study cells.  The goal of understanding cell biology methods is especially...

    Keywords: ABC transporter familyDifferential centrifugationImmunoblottingImmunofluorescence assayProtein localizationPurifying organellesSDS-PAGE

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    Cell Signaling Pathways - a Case Study Approach
    Signaling and gene expression are fundamental to cell biology and developmental biology. Although these topics are highly interrelated, they typically appear in separate units in a course. We use a...

    Keywords: signal transductiongene expressionCell communicationgenetic disordersregulation of enzyme activity

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    The Perfect Brew: An Activity Demonstrating Cell Counting and Hemocytometer Use
    In this activity, students will explore the use of a hemocytometer for counting cells, demonstrate the relationship between the grid seen in the microscope with volume of liquid in suspension and...

    Keywords: RatiosmicrobiologyqbccCellular and Molecular BiologyUnderstanding fractionsconverting unitschanging scalesmeasurements

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    Why are Cells Small? Surface Area to Volume Ratio
    This module explores surface area to volume ratios in a cube and sphere in relation to cell size.

    Keywords: introductory biologygraphingRatiosOpenStaxqbccmanipulate equationsCellular and Molecular BiologyUse elementary functionsCreate graphsInterpret graphsRates and ProportionsSolving Equations and Inequalitiesinterpret tables

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.

    Keywords: spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions

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    3-D Printing Models of Cell Organelles and Flowers
    This hands-on module features active learning using 3-D printing technology to teach middle school students about physical scientific models and cell organelles.
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    Module 4: Removal of Introns from pre-mRNA by Splicing
    In this module, students will learn to identify splice donor and acceptor sites that are best supported by RNA-Seq data, and use the canonical splice donor and splice acceptor sequences to identify...

    Keywords: geneticsdata visualizationmolecular biologygenomicsexonintronsplicingSimilarity searchesRNA Maturation

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

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    Monkey Opsins
    This case will examine the evolution of trichromatic vision in old world monkeys.

    Keywords: modulephylogeneticsecologycell biologymolecular geneticsResources @ EvoEd

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs...

    Keywords: fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills

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    Fatty Acid Induction of Lipid Droplets in Cancer Cells
    There is a growing need for the development and communication of cell culture-based laboratory activities specifically designed for undergraduate students. This multi-week laboratory activity...

    Keywords: Course based undergraduate researchCell ImagingLive Cell Staining

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    Cellular Respiration and pH: blocking the electron transport chain and its effects on the proton gradient, pH, and ATP production
    This module contains exercises designed to help students describe the stages of cellular respiration and quantify the energy molecules produced. Students will predict the region of higher proton...

    Keywords: introductory biologyQuantitative reasoningquantitative biologyinterdisciplarycell functionInterpreting GraphsATPpHCellular RespirationEnergy transformationsElectron flowNIQBC2. Data and GraphsC4. mathematical modelsC1. Numeracyproton gradientelectron transportelectron transport blockersFADH2chemiosmosisATP synthaseNADHproton concentration

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    From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design
    Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important...

    Keywords: experimental designC. elegansCre/LoxPFate mapheart developmentheart regenerationmousereporter constructzebrafish

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    CURESUB Lecture 5 - OMICS
    s assistant professor in the department of medicine at Rutgers Robert Wood Johnson Medical School, Manisha Bajpai, PhD., led the Gastroenterology division’s clinical and translational research...
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    Nastic Movements in Plants
    This module introduces an osmotic model in the context of understanding plants' capability of rapidly adapting to changes in their environment. It is intended for an introductory biology audience.

    Keywords: plant physiologyhyperbolic equationsOpenStaxinterpreting modelsnastic movements

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    Efficiency of ATP Prodution
    This module introduces the efficiency of ATP production in the context of understanding glycolysis and endergonic reactions. It is intended for an introductory biology audience.

    Keywords: RatiosOpenStaxCellular ProcessesEndergonic ReactionsATPGlycolysis

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    Applying Universal Design for Learning (UDL) Principles to Case Studies
    This is a presentation for the 2022 BIOME meeting.
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    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing...

    Keywords: genomicstranscriptionsignaling

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    A Structured Inquiry-Based Module for the Undergraduate Cell Biology Laboratory That Teaches Fundamental Concepts of Cell Differentiation
    Pedagogical research in science education has shown that students effectively learn science by doing science. As a result, there is increased interest in bringing research-like experiences into the...

    Keywords: fluorescence microscopygene expressionpolymerase chain reactionCell Structurecell culturewestern blottingdifferentiationreverse transcription

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